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Cabazitaxel
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Cabazitaxel dosage & frequency?
I have been offered
Cabazitaxel
in one of three dosages: either 25mg ( FDA original recommendation), 20 ( equally effective as per Firstana Trial ) or 16 ( untested). The choice is mine. The frequency at my hospital is every 3 weeks. Has anyone had
Cabazitaxel
on a weekly basis &/or at 16mg?
I have been offered
Cabazitaxel
in one of three dosages: either 25mg ( FDA original recommendation), 20 ( equally effective as per Firstana Trial ) or 16 ( untested). The choice is mine. The frequency at my hospital is every 3 weeks. Has anyone had
Cabazitaxel
on a weekly basis &/or at 16mg?
baltha
in
Advanced Prostate Cancer
3 years ago
CHAMP Clinical Trial Time for this kid
Given my prostate has evolved to Gleason 10 and neuroendocrine (small cell) I'm in the process of qualifying for the CHAMP trial: Nivolumab, ipilimumab,
cabazitaxel
and carboplatin.
Given my prostate has evolved to Gleason 10 and neuroendocrine (small cell) I'm in the process of qualifying for the CHAMP trial: Nivolumab, ipilimumab,
cabazitaxel
and carboplatin.
HerbieP
in
Advanced Prostate Cancer
3 years ago
Are all AR inhibitors the same?
MO now prescribes
cabazitaxel
(Jevtana). My question: Why not try enzalutamide first? MO says all AR inhibitors are the same: "They change one molecule and sell it as a new drug."
MO now prescribes
cabazitaxel
(Jevtana). My question: Why not try enzalutamide first? MO says all AR inhibitors are the same: "They change one molecule and sell it as a new drug."
yeatz
in
Advanced Prostate Cancer
3 years ago
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Update on Jim July 2021: (Cabazitaxel, ?Immunotherapy)
In January 2021, Jim began 10 treatments of
Cabazitaxel
-45 mg every 3 weeks.
In January 2021, Jim began 10 treatments of
Cabazitaxel
-45 mg every 3 weeks.
GrizzlyMama
in
Advanced Prostate Cancer
3 years ago
Xtandi stopped working, Jevtana next??
We have been told Xtandi / Enzalutamide has stopped working, have to move to the next treatment Chemo - Jevtana /
Cabazitaxel
.
I just want to know if there are other treatments to consider at this point? Or Jevtana is the right next step?
We have been told Xtandi / Enzalutamide has stopped working, have to move to the next treatment Chemo - Jevtana /
Cabazitaxel
.
I just want to know if there are other treatments to consider at this point? Or Jevtana is the right next step?
Cheerr
in
Advanced Prostate Cancer
3 years ago
On Cabazitaxel, PSA started increasing......PSA->15 (1 Feb 21)->13.64 (#post 3 cycle, 5 April)->15.3 (#6 cycle, 14 June)
We are currently on
(post Abireterone->Docetaxel(10 cycle)). completed 6 cycles, PSA started increasing however Dr. suggested to complete 10 cycles as disease seems stable : PSA->15(1 Feb 21)->13.64 (#post 3 cycle 5 April)->15.3 (#6 cycle 14 June). 1.
We are currently on
(post Abireterone->Docetaxel(10 cycle)). completed 6 cycles, PSA started increasing however Dr. suggested to complete 10 cycles as disease seems stable : PSA->15(1 Feb 21)->13.64 (#post 3 cycle 5 April)->15.3 (#6 cycle 14 June). 1.
pka21
in
Advanced Prostate Cancer
3 years ago
Dr Oliver Sartor of Tulane Univ. on Cabazitaxel for later stage Castration Resistant mPCa (CRmPCa). Vs Docetaxel and Zytiga.
https://www.targetedonc.com/view/
cabazitaxel
-advances-later-line-treatment-in-metastatic-crpc-setting
https://www.targetedonc.com/view/
cabazitaxel
-advances-later-line-treatment-in-metastatic-crpc-setting
Spyder54
in
Advanced Prostate Cancer
3 years ago
Update on our Cabazitaxel treatment, Any Experience/suggestions pls?
Any experiences/suggestions on
, how long and well it works to control the disease?
Any experiences/suggestions on
, how long and well it works to control the disease?
pka21
in
Advanced Prostate Cancer
3 years ago
Article: 'Major Milestone' in mCRPC: Radiopharmaceutical Boosts Survival
These results showed that 177Lu PSMA-617 was more active than
cabazitaxel
against mCRPC and led to fewer grade 3–4 adverse events.
These results showed that 177Lu PSMA-617 was more active than
cabazitaxel
against mCRPC and led to fewer grade 3–4 adverse events.
GregHouston
in
Advanced Prostate Cancer
3 years ago
Next Treatment Plan Thoughts?
Recent PET scan shows 3 spots coming back Doctor#1 would like to put put me on an Oral Pill (2nd Gen Anti Androgen) Doctor# 2 would like to start 8 total infusions of
Cabazitaxel
/Carboplatin with a scan after the 4th infusion. I am 52 years old. Your thoughts? Thank you
Recent PET scan shows 3 spots coming back Doctor#1 would like to put put me on an Oral Pill (2nd Gen Anti Androgen) Doctor# 2 would like to start 8 total infusions of
Cabazitaxel
/Carboplatin with a scan after the 4th infusion. I am 52 years old. Your thoughts? Thank you
cuphalffull1
in
Advanced Prostate Cancer
3 years ago
What kind timeline are we looking at?
/29/2015- 4/15/2016 - Xtandi 9/2/2018- 9/2019 - Apalutamide 1/15/2020- June 2020 - Olaparib 150 mg PO BID started on 8/20/2020, dose reduced to 75 mg PO BID on 10/13/2020, discontinued due to side effects on 06/29/2021 - palliative RT to prostate and inferior ramus on 1/20/2021 Current Treatment: -
Cabazitaxel
/29/2015- 4/15/2016 - Xtandi 9/2/2018- 9/2019 - Apalutamide 1/15/2020- June 2020 - Olaparib 150 mg PO BID started on 8/20/2020, dose reduced to 75 mg PO BID on 10/13/2020, discontinued due to side effects on 06/29/2021 - palliative RT to prostate and inferior ramus on 1/20/2021 Current Treatment: -
Cabazitaxel
KinkyPinky
in
Advanced Prostate Cancer
3 years ago
New York Times article on the recent Lutetium-177–PSMA-617 study [VISION] + NEJM paper
Nearly all the enrolled patients (≥97%) had already received docetaxel, and 38% had already received
cabazitaxel
.
Nearly all the enrolled patients (≥97%) had already received docetaxel, and 38% had already received
cabazitaxel
.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Zytiga &Dexamethasone or what?
Cabazitaxel
is not available in my country. 3. Do you know anyone who is under ADT treatment but has BPH? Thank you for your sharing and advice
Cabazitaxel
is not available in my country. 3. Do you know anyone who is under ADT treatment but has BPH? Thank you for your sharing and advice
Hidden
in
Advanced Prostate Cancer
3 years ago
Jevtana failing?
gone up to 43.5 -an increase of 11.4 A bone scan and CT scan taken last week showed increased activity in 2 spots (Dr says it could be a flare response....The PSA results from today were released after speaking to the Dr) When we left the office today, the plan was to go ahead with the carboplatin+
cabazitaxel
gone up to 43.5 -an increase of 11.4 A bone scan and CT scan taken last week showed increased activity in 2 spots (Dr says it could be a flare response....The PSA results from today were released after speaking to the Dr) When we left the office today, the plan was to go ahead with the carboplatin+
cabazitaxel
ellie2211
in
Advanced Prostate Cancer
3 years ago
Well...on the Day After my first Chemo with Cabazitaxel...1/2 dosage every 3 weeks. I felt GREAT yesterday after it...
and today I had to go back for a platelet transfusion...as they had dropped to 18. My Neulasta Onpro went off at 6 pm tonight...and even then...(I'm taking Claritin) I am still feeling great all day. I do have incredible dry mouth and my taste is off. I tried sucking on ice a little. I also put ice
and today I had to go back for a platelet transfusion...as they had dropped to 18. My Neulasta Onpro went off at 6 pm tonight...and even then...(I'm taking Claritin) I am still feeling great all day. I do have incredible dry mouth and my taste is off. I tried sucking on ice a little. I also put ice
greatjohn
in
Advanced Prostate Cancer
3 years ago
Continue Lupron after continuing PSA rise?
He has had Provenge, Xtandi, Dosetaxel,
Cabazitaxel
and all worked for a good time, but his PSA has been steadily and firmly rising and new bone Mets for the past few months.
He has had Provenge, Xtandi, Dosetaxel,
Cabazitaxel
and all worked for a good time, but his PSA has been steadily and firmly rising and new bone Mets for the past few months.
NWLiving
in
Advanced Prostate Cancer
3 years ago
Cabazitaxel vs Abiraterone or Enzalutamide in Poor-Prognosis Metastatic Castration-Resistant Prostate Cancer
The clinical benefit rate was higher with
cabazitaxel
treatment (80% vs 62%). Overall survival was numerically longer (median 37 vs 15.5 months) but did not reach statistical significance.
The clinical benefit rate was higher with
cabazitaxel
treatment (80% vs 62%). Overall survival was numerically longer (median 37 vs 15.5 months) but did not reach statistical significance.
Balsam01
in
Advanced Prostate Cancer
3 years ago
Keytruda, a question probably no one can answer.
He has done Docetaxel early on so this would probably be
cabazitaxel
. It breaks our hearts to see him so depressed. He is young only in his 50s with a young family. He has a very supportive wife and lots of family and friends who love him.
He has done Docetaxel early on so this would probably be
cabazitaxel
. It breaks our hearts to see him so depressed. He is young only in his 50s with a young family. He has a very supportive wife and lots of family and friends who love him.
Faith1111
in
Advanced Prostate Cancer
3 years ago
First major pathological fracture
Dr would like him to try
Cabazitaxel
but husband is not sure given his bad experience with Docetaxel. Dr also considering provenge. We’re literally at a crossroads on a couple fronts. Any advice appreciated.
Dr would like him to try
Cabazitaxel
but husband is not sure given his bad experience with Docetaxel. Dr also considering provenge. We’re literally at a crossroads on a couple fronts. Any advice appreciated.
WVtwinsmama
in
Advanced Prostate Cancer
3 years ago
Radioligand (LU177) shows benefit over chemotherapy (Cabazitaxel) in prostate cancer
More serious adverse events occurred in 33% of men in the [177Lu]Lu-PSMA-617 group versus 53% of men in the
cabazitaxel
group.
More serious adverse events occurred in 33% of men in the [177Lu]Lu-PSMA-617 group versus 53% of men in the
cabazitaxel
group.
HopingForTheBest1
in
Advanced Prostate Cancer
3 years ago
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