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Keytruda, a question probably no one can answer.
He has done Docetaxel early on so this would probably be
cabazitaxel
. It breaks our hearts to see him so depressed. He is young only in his 50s with a young family. He has a very supportive wife and lots of family and friends who love him.
He has done Docetaxel early on so this would probably be
cabazitaxel
. It breaks our hearts to see him so depressed. He is young only in his 50s with a young family. He has a very supportive wife and lots of family and friends who love him.
Faith1111
in
Advanced Prostate Cancer
3 years ago
First major pathological fracture
Dr would like him to try
Cabazitaxel
but husband is not sure given his bad experience with Docetaxel. Dr also considering provenge. We’re literally at a crossroads on a couple fronts. Any advice appreciated.
Dr would like him to try
Cabazitaxel
but husband is not sure given his bad experience with Docetaxel. Dr also considering provenge. We’re literally at a crossroads on a couple fronts. Any advice appreciated.
WVtwinsmama
in
Advanced Prostate Cancer
3 years ago
Radioligand (LU177) shows benefit over chemotherapy (Cabazitaxel) in prostate cancer
More serious adverse events occurred in 33% of men in the [177Lu]Lu-PSMA-617 group versus 53% of men in the
cabazitaxel
group.
More serious adverse events occurred in 33% of men in the [177Lu]Lu-PSMA-617 group versus 53% of men in the
cabazitaxel
group.
HopingForTheBest1
in
Advanced Prostate Cancer
3 years ago
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What next? Abiraterone->Docetaxel->Cabazitaxel-> ?
3.How long
cabazitaxel
, Enzalutamide (Xtandi) generally work in mCRPC setting post-Abiraterone & Docetaxel? 4.Rechallenging Zytiga ?
3.How long
cabazitaxel
, Enzalutamide (Xtandi) generally work in mCRPC setting post-Abiraterone & Docetaxel? 4.Rechallenging Zytiga ?
pka21
in
Advanced Prostate Cancer
3 years ago
A look at the next generation of Androgen Receptor therapies--AR Degraders/PROTACS
Today, people turn to things like Provenge, Xofigo, Lu-177 or
Cabazitaxel
, but in the future, these kind of drugs will be the answer also. But... what is a PROTAC /AR Degrader??
Today, people turn to things like Provenge, Xofigo, Lu-177 or
Cabazitaxel
, but in the future, these kind of drugs will be the answer also. But... what is a PROTAC /AR Degrader??
NPfisherman
in
Fight Prostate Cancer
3 years ago
Docetaxel vs. Cabazitaxel--effectiveness?
Anyone here had success with
cabazitaxel
after failure of docetaxel?
Anyone here had success with
cabazitaxel
after failure of docetaxel?
WildRose6
in
Advanced Prostate Cancer
4 years ago
NICE not playing nice again.
Though clinical trial evidence showed that study subjects taking Lynparza had improved progression-free survival and overall survival, NICE said that there is no direct comparison of Lynparza to the current standard of care for metastatic prostate cancer, which includes chemotherapy drugs docetaxel,
cabazitaxel
Though clinical trial evidence showed that study subjects taking Lynparza had improved progression-free survival and overall survival, NICE said that there is no direct comparison of Lynparza to the current standard of care for metastatic prostate cancer, which includes chemotherapy drugs docetaxel,
cabazitaxel
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Chemo and Genetics
I'm responding well to folfiri chemo after having a recurrence following platinum chemo and not responding to
cabazitaxel
. I've lived almost 14 months since my neuroendocrine diagnosis.
I'm responding well to folfiri chemo after having a recurrence following platinum chemo and not responding to
cabazitaxel
. I've lived almost 14 months since my neuroendocrine diagnosis.
tom67inMA
in
Advanced Prostate Cancer
3 years ago
The same mRNA science that brought us the COVID-19 vaccine is being studied for mCRPCa
., abiraterone or enzalutamide, docetaxel,
cabazitaxel
) or cannot tolerate any of these therapies. These lines of therapy include life-prolonging therapies administered in the metastatic hormone-sensitive setting.”
., abiraterone or enzalutamide, docetaxel,
cabazitaxel
) or cannot tolerate any of these therapies. These lines of therapy include life-prolonging therapies administered in the metastatic hormone-sensitive setting.”
tallguy2
in
Advanced Prostate Cancer
3 years ago
Results from Foundation One Cdx, IHC, Neuroendocrine tests
My husband tried and failed on Zytiga, chemo (docetaxel), Zytiga, Lu177 and now trying Xtandi before moving on to
cabazitaxel
and possibly with Xofigo but Im not sure if I can source this one out in Singapore because its not available here in the Philippines.
My husband tried and failed on Zytiga, chemo (docetaxel), Zytiga, Lu177 and now trying Xtandi before moving on to
cabazitaxel
and possibly with Xofigo but Im not sure if I can source this one out in Singapore because its not available here in the Philippines.
dvcarola2
in
Advanced Prostate Cancer
4 years ago
Lu 177 PSMA vs Cabazitaxel (Jevtana) in patients with mCRPC previously treated with Docetaxel and with a progressing PSA with values >/=20.
More patients had a =/>50% decrease in the PSA when treated with Lu 177 PSMA than patients treated with
Cabazitaxel
(Jevtana)..
More patients had a =/>50% decrease in the PSA when treated with Lu 177 PSMA than patients treated with
Cabazitaxel
(Jevtana)..
tango65
in
Advanced Prostate Cancer
4 years ago
REGN 5678 Trial
Hi folks, I have posted in a few other discussions on this board, but I wanted to find out if anyone has experienced or has an opinion about this trial: https://clinicaltrials.gov/ct2/show/NCT03972657 I have gone the gamut, from Docetaxel to Xtandi to
Cabazitaxel
to Xofigo, with 2 clinical trials with
Hi folks, I have posted in a few other discussions on this board, but I wanted to find out if anyone has experienced or has an opinion about this trial: https://clinicaltrials.gov/ct2/show/NCT03972657 I have gone the gamut, from Docetaxel to Xtandi to
Cabazitaxel
to Xofigo, with 2 clinical trials with
tomtom9148
in
Advanced Prostate Cancer
4 years ago
Update and Questions on Cabazitaxel
What is your experience with
Cabazitaxel
(Jetvana)? 2. Is
Cabazitaxel
worse, better, or about the same as Docataxel? 3. What is your experience with a medi-port? We’re praying it’s a lot less invasive than the CVC-Central vena catheter. The CVC definitely interfered with Jim’s QOL.
What is your experience with
Cabazitaxel
(Jetvana)? 2. Is
Cabazitaxel
worse, better, or about the same as Docataxel? 3. What is your experience with a medi-port? We’re praying it’s a lot less invasive than the CVC-Central vena catheter. The CVC definitely interfered with Jim’s QOL.
GrizzlyMama
in
Advanced Prostate Cancer
4 years ago
Anyone have experience or knowledge of AZD4635
Dad has been recommended for a clinical trial combing AZD4635, Dyrvalumab,
Cabazitaxel
and Granulocyte-colony stimulating factor. It's phase 2 and thought maybe someone had knowledge of phase 1.
Dad has been recommended for a clinical trial combing AZD4635, Dyrvalumab,
Cabazitaxel
and Granulocyte-colony stimulating factor. It's phase 2 and thought maybe someone had knowledge of phase 1.
2zuzu612
in
Advanced Prostate Cancer
4 years ago
Remember two weeks ago when I freaked out?
Had my scan yesterday to see how well
cabazitaxel
is working to clean up my neuroendocrine cancer, and if anything, it's been fertilizing it. My liver looked awful.
Had my scan yesterday to see how well
cabazitaxel
is working to clean up my neuroendocrine cancer, and if anything, it's been fertilizing it. My liver looked awful.
tom67inMA
in
Advanced Prostate Cancer
4 years ago
"breaks the blood brain barrier" scares me
I have noticed that it is said of
Cabazitaxel
that it "breaks the blood brain barrier". Docetaxel scrambled my brain effectively but does not "break the blood brain barrier". Is this a cause for concern? All best, Baltha
I have noticed that it is said of
Cabazitaxel
that it "breaks the blood brain barrier". Docetaxel scrambled my brain effectively but does not "break the blood brain barrier". Is this a cause for concern? All best, Baltha
baltha
in
Advanced Prostate Cancer
4 years ago
Quick Update
In mid December I felt so awful on
cabazitaxel
that I was ready to pack it in and focus on making myself comfortable. Then I realized that getting the cancer out of my liver would make me comfortable and the rest is history.
In mid December I felt so awful on
cabazitaxel
that I was ready to pack it in and focus on making myself comfortable. Then I realized that getting the cancer out of my liver would make me comfortable and the rest is history.
tom67inMA
in
Advanced Prostate Cancer
4 years ago
Cabazitaxel Cycle 2
The side effects are past their peak, but I'm still tired and sore and moody. Read my blog to find out about the little road trip I took today to avoid another emotional meltdown. https://tominmotion.blogspot.com/2020/11/quick-post.html
The side effects are past their peak, but I'm still tired and sore and moody. Read my blog to find out about the little road trip I took today to avoid another emotional meltdown. https://tominmotion.blogspot.com/2020/11/quick-post.html
tom67inMA
in
Advanced Prostate Cancer
4 years ago
Freaking out over latest blood test results
I just started my third cycle of
cabazitaxel
chemotherapy and have a scan scheduled for December 15th. The blood test results from Monday are not encouraging. Liver enzymes and LDH are all above normal and at record high levels for me.
I just started my third cycle of
cabazitaxel
chemotherapy and have a scan scheduled for December 15th. The blood test results from Monday are not encouraging. Liver enzymes and LDH are all above normal and at record high levels for me.
tom67inMA
in
Advanced Prostate Cancer
4 years ago
PSA up to 112, Xofigo treatment now
I have had Lupron, Doxcetaxal, PROSTVAC, Xtandi, Zytiga, Immuneotherapy trial,
Cabazitaxel
, and now Awaiting my 3rd dose of Xofigo. My PSA has rose steadily since the Xtandi failed in October of 2019, now up to 112 after prior count of 65 in October of 2020.
I have had Lupron, Doxcetaxal, PROSTVAC, Xtandi, Zytiga, Immuneotherapy trial,
Cabazitaxel
, and now Awaiting my 3rd dose of Xofigo. My PSA has rose steadily since the Xtandi failed in October of 2019, now up to 112 after prior count of 65 in October of 2020.
tomtom9148
in
Advanced Prostate Cancer
4 years ago
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