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Cabazitaxel and chemo side effects
Hello Everyone, Hope everything is going as well as it can be. I have some Qs for people first handily experiencing or going through chemo. Grandad is currently on second line chemo for castrate resistant prostate cancer. He is currently lacking a lot of energy, feeling very tired and getting bad muscle
Hello Everyone, Hope everything is going as well as it can be. I have some Qs for people first handily experiencing or going through chemo. Grandad is currently on second line chemo for castrate resistant prostate cancer. He is currently lacking a lot of energy, feeling very tired and getting bad muscle
Nicholas27
in
Advanced Prostate Cancer
3 years ago
Adventures with Cabazitaxel
Hoping the switch to
Cabazitaxel
does the job. Fingers crossed đ€ MO said, if no PSA drop after two sessions, then may add Carboplatin. Fasted two days prior. Took 10mg Prednisone, and will do that daily thr chemos.
Hoping the switch to
Cabazitaxel
does the job. Fingers crossed đ€ MO said, if no PSA drop after two sessions, then may add Carboplatin. Fasted two days prior. Took 10mg Prednisone, and will do that daily thr chemos.
dockam
in
Advanced Prostate Cancer
3 years ago
Update After 3 Cabazitaxel Treatments.
Thanks in advance for your collective thoughts on what tests to evaluate the effectiveness of
Cabazitaxel
in a timely fashion. Best Philly
Thanks in advance for your collective thoughts on what tests to evaluate the effectiveness of
Cabazitaxel
in a timely fashion. Best Philly
Philly13
in
Advanced Prostate Cancer
3 years ago
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Can I try A rechallenge with Xtandi after using docetaxel and cabazitaxel?
Since then have failed docetaxel and now
cabazitaxel
/carboplatin. Planning on xofigo next but my hemoglobin has been in the 8âs since beginning chemo. Could retrying xtandi benefit me at all while I wait for my hemoglobin to recover ?
Since then have failed docetaxel and now
cabazitaxel
/carboplatin. Planning on xofigo next but my hemoglobin has been in the 8âs since beginning chemo. Could retrying xtandi benefit me at all while I wait for my hemoglobin to recover ?
Peterd110
in
Advanced Prostate Cancer
3 years ago
Continued increase in CEA & PSA Markers
The Trial initially included six cycles (Induction Phase) of
Cabazitaxel
/Carboplatin/Cetrelimab. Throughout this timeframe my PSA has risen from 4.4 in May 2021 to now 14.65 as of yesterday. My CEA has also elevated from 8.1 in December 2021 to 13.9 as of yesterday.
The Trial initially included six cycles (Induction Phase) of
Cabazitaxel
/Carboplatin/Cetrelimab. Throughout this timeframe my PSA has risen from 4.4 in May 2021 to now 14.65 as of yesterday. My CEA has also elevated from 8.1 in December 2021 to 13.9 as of yesterday.
kklott01
in
Advanced Prostate Cancer
3 years ago
Latest Axumin scan - onwards to Cabazitaxel đ
Hey gang, Latest scan showed a new spot on left of prostate and the same 1cm iliac lymph node with high uptake. Also maybe another suspicious area So, Kaiser MO has agreed to 6 Cabazitaxels, starting on 10/29/21 and monitoring the PSA, possibly adding Carboplatin after the 2nd or 3rd session. This
Hey gang, Latest scan showed a new spot on left of prostate and the same 1cm iliac lymph node with high uptake. Also maybe another suspicious area So, Kaiser MO has agreed to 6 Cabazitaxels, starting on 10/29/21 and monitoring the PSA, possibly adding Carboplatin after the 2nd or 3rd session. This
dockam
in
Advanced Prostate Cancer
3 years ago
Duke "CHAMP" trial update
carboplatin,
cabazitaxel
, nivolumab and ipilimumab combined to slow advanced prostate cancer? Answer: We don't know yet. My PSA numbers have dropped significantly, but I'm very advanced so they dance around a bit. Lower overall but they jump back up at times.
carboplatin,
cabazitaxel
, nivolumab and ipilimumab combined to slow advanced prostate cancer? Answer: We don't know yet. My PSA numbers have dropped significantly, but I'm very advanced so they dance around a bit. Lower overall but they jump back up at times.
HerbieP
in
Advanced Prostate Cancer
3 years ago
Neuroendocrine Prostate Cancer [NEPC]
Sometimes, platinum is combined with taxanes, since taxanes such as docetaxel and
cabazitaxel
are used as gold standard chemotherapy for CRPC (53,54). Although an initial response is observed in some cases, in general, the duration of the response is short (55).
Sometimes, platinum is combined with taxanes, since taxanes such as docetaxel and
cabazitaxel
are used as gold standard chemotherapy for CRPC (53,54). Although an initial response is observed in some cases, in general, the duration of the response is short (55).
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Reduce Cabazitaxel dose or add a week to the period?
Which is better, 4 week
Cabazitaxel
schedule or reduced dose with 3 week schedule? It triggers AFIB for 4 or 5 days in the middle and I'm hoping to spend a bit more time out of AFIB.
Which is better, 4 week
Cabazitaxel
schedule or reduced dose with 3 week schedule? It triggers AFIB for 4 or 5 days in the middle and I'm hoping to spend a bit more time out of AFIB.
mikell
in
Advanced Prostate Cancer
3 years ago
Androgen Receptor [AR] Axis Therapies
Prednisone plus
cabazitaxel
or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010;376:1147-1154. Kantoff PW, Higano CS, Shore ND, et al.
Prednisone plus
cabazitaxel
or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010;376:1147-1154. Kantoff PW, Higano CS, Shore ND, et al.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Hopeful my Jeff responds to carboplatin/cabazitaxel
My Jeff had labs Monday and his 2nd infusion of carboplatin/
cabazitaxel
Tuesday. Labs proved disappointing. Jeffâs PSA is up from 76.5 to 101. Jeffâs oncologist said âlets not worry yetâ. Jeff is scheduled for additional labs and another PET scan starting mid December.
My Jeff had labs Monday and his 2nd infusion of carboplatin/
cabazitaxel
Tuesday. Labs proved disappointing. Jeffâs PSA is up from 76.5 to 101. Jeffâs oncologist said âlets not worry yetâ. Jeff is scheduled for additional labs and another PET scan starting mid December.
Pancake_Lefse
in
Advanced Prostate Cancer
3 years ago
Docetaxel , thank you for your Service
Well the PSA is creeping back up into the low 5's , last bone scan showed some spreading , so we have determined that Docetaxel is no longer doing the job , so we are switching over to Jevtana , great name , hoping for the best , so
Cabazitaxel
it is , if anyone else is taking this fine poison into
Well the PSA is creeping back up into the low 5's , last bone scan showed some spreading , so we have determined that Docetaxel is no longer doing the job , so we are switching over to Jevtana , great name , hoping for the best , so
Cabazitaxel
it is , if anyone else is taking this fine poison into
Mollygrace666
in
Advanced Prostate Cancer
3 years ago
Neutrophil:Lymphocyte Ratio [NLR] in patients with mCRPC treated with Cabazitaxel v. Abiraterone or Enzalutamide in the CARD study
Conversely, the activity of
cabazitaxel
is retained irrespective of NLR. Keywords: abiraterone;
cabazitaxel
; enzalutamide; metastatic castration-resistant prostate cancer; neutrophil-to-lymphocyte ratio; prognostic factor. Copyright © 2021 The Authors. Published by Elsevier Ltd..
Conversely, the activity of
cabazitaxel
is retained irrespective of NLR. Keywords: abiraterone;
cabazitaxel
; enzalutamide; metastatic castration-resistant prostate cancer; neutrophil-to-lymphocyte ratio; prognostic factor. Copyright © 2021 The Authors. Published by Elsevier Ltd..
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Thursday 9/9/2021 was D for Decision Day--Locked and Loaded for Chemotherapy
We talked about Docetaxel and
Cabazitaxel
. He said he would lobby for
Cabazitaxel
. PSA readings have always been volatile, but the last three months seem out of control.
We talked about Docetaxel and
Cabazitaxel
. He said he would lobby for
Cabazitaxel
. PSA readings have always been volatile, but the last three months seem out of control.
Philly13
in
Advanced Prostate Cancer
3 years ago
Some questions answered, some answers questioned, and Chemotherapy scheduled.
Cabazitaxel
is ordered and we should know this week if the insurance will cover it, if not we will put docetaxel in ASAP. We should be able to treat this week or next."
Cabazitaxel
is ordered and we should know this week if the insurance will cover it, if not we will put docetaxel in ASAP. We should be able to treat this week or next."
Philly13
in
Advanced Prostate Cancer
3 years ago
Cabazitaxel not working anymore seems, PSMA Scan & PSA shows progression
Our Dr. suggested below options:
Cabazitaxel
+Enzalutamide (Phase II data)/ Enzalutamide/PSMA therapy with Enzalutamide.
Our Dr. suggested below options:
Cabazitaxel
+Enzalutamide (Phase II data)/ Enzalutamide/PSMA therapy with Enzalutamide.
pka21
in
Advanced Prostate Cancer
3 years ago
21Aug21 TheraP Study: Lu177-PSMA vs Cabazitaxel
A randomised phase II trial of 177Lu-PSMA-617 (Lu-PSMA) theranostic versus
cabazitaxel
in metastatic castration resistant prostate cancer (mCRPC) progressing after docetaxel: Initial results are much more positive than earlier reported in the USA...now this is a Phase II trial (Phase III trials are scheduled
A randomised phase II trial of 177Lu-PSMA-617 (Lu-PSMA) theranostic versus
cabazitaxel
in metastatic castration resistant prostate cancer (mCRPC) progressing after docetaxel: Initial results are much more positive than earlier reported in the USA...now this is a Phase II trial (Phase III trials are scheduled
RMontana
in
Active Surveillance - Prostate Cancer
3 years ago
Duke CHAMP clinical Trial Update
I've had my first infusion of the two chemos
cabazitaxel
and carboplatin and two immuno-therapies (nivolumab and ipilimumab) 14 days ago. My side effects have been less than what docetaxel were.
I've had my first infusion of the two chemos
cabazitaxel
and carboplatin and two immuno-therapies (nivolumab and ipilimumab) 14 days ago. My side effects have been less than what docetaxel were.
HerbieP
in
Advanced Prostate Cancer
3 years ago
Brain looks great!!!
Jeff has only had 2 infusions of carboplatin/
cabazitaxel
. Perhaps PSA flare or just needs a little more time to work, whatever the case, Iâm not ready to believe chemo might not be working.
Jeff has only had 2 infusions of carboplatin/
cabazitaxel
. Perhaps PSA flare or just needs a little more time to work, whatever the case, Iâm not ready to believe chemo might not be working.
Pancake_Lefse
in
Advanced Prostate Cancer
3 years ago
Preparation for Treatment Decisions 90 Days after Immunotherapy Stopped.
I will try to make it into a math problem that we can both solve in the same terms, knowing there is not perfect answer that will provide a cure. 1.Is
Cabazitaxel
preferable to Docetaxel? 2.Will chemo be combined with any other treatment if that is the choice?
I will try to make it into a math problem that we can both solve in the same terms, knowing there is not perfect answer that will provide a cure. 1.Is
Cabazitaxel
preferable to Docetaxel? 2.Will chemo be combined with any other treatment if that is the choice?
Philly13
in
Advanced Prostate Cancer
3 years ago
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