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đź“š Research 101: What is a Clinical Trial
[u]
What is a clinical trial?
[/u] A clinical trial is a research study that determines whether new treatments are safe and effective for humans. Clinical trials are strictly controlled to ensure the safety of the people taking part. [u]
Who comes up with clinical trials?
[/u] Ideas for
[u]
What is a clinical trial?
[/u] A clinical trial is a research study that determines whether new treatments are safe and effective for humans. Clinical trials are strictly controlled to ensure the safety of the people taking part. [u]
Who comes up with clinical trials?
[/u] Ideas for
AnnaHU
HealthUnlocked
in
Research Opportunities
2 years ago
Phase 1b trial shows reformulated Niclosamide has promise for CRPC
Niclosamide in prostate cancer: An inhibitor of AR-V7, a mitochondrial uncoupler, or more? Author links open overlay panelMinasSakellakisabShow moreOutlineShareCite https://doi.org/10.1016/j.ctarc.2023.100685 Get rights and contentUnder a Creative Commons licenseOpen accessHighlights •A recent phase
Niclosamide in prostate cancer: An inhibitor of AR-V7, a mitochondrial uncoupler, or more? Author links open overlay panelMinasSakellakisabShow moreOutlineShareCite https://doi.org/10.1016/j.ctarc.2023.100685 Get rights and contentUnder a Creative Commons licenseOpen accessHighlights •A recent phase
Graham49
in
Advanced Prostate Cancer
2 years ago
Community Guidelines
Community Name (“Research Opportunities”)
About This Community
The purpose of this online community is to stimulate dialogue, and encourage ongoing discussion on Research Opportunities and Research-related topics, as well as provide you with a better understanding of clinical trials
Community Name (“Research Opportunities”)
About This Community
The purpose of this online community is to stimulate dialogue, and encourage ongoing discussion on Research Opportunities and Research-related topics, as well as provide you with a better understanding of clinical trials
AnnaHU
HealthUnlocked
in
Research Opportunities
2 years ago
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Small molecule ACK1 inhibitor (R)-9b - third generation AR receptor - clinical trial I in 2023
Technogenesys will start a trial in 2023, be prepared: Thus,, there is an acute need for next generation of inhibitor that can overcome Enzalutamide and Abiraterone resistance. We have identified (R)-9b as a `third generation' of AR-antagonist, which has ability to overcome Enzalutamide and abiraterone-resistant
Technogenesys will start a trial in 2023, be prepared: Thus,, there is an acute need for next generation of inhibitor that can overcome Enzalutamide and Abiraterone resistance. We have identified (R)-9b as a `third generation' of AR-antagonist, which has ability to overcome Enzalutamide and abiraterone-resistant
Hidden
in
Advanced Prostate Cancer
2 years ago
just started on levothyroxine
I have been taking levothyroxine for just over 2 months. My gp started me on a very low dose of 25mg and I’m due bloods in a month. After about 4 weeks it felt like my tiredness had improved and I was feeling more energetic but the last few weeks I feel back to square one again. I had a partial thyroidectomy
I have been taking levothyroxine for just over 2 months. My gp started me on a very low dose of 25mg and I’m due bloods in a month. After about 4 weeks it felt like my tiredness had improved and I was feeling more energetic but the last few weeks I feel back to square one again. I had a partial thyroidectomy
Amyob12
in
Thyroid UK
2 years ago
Abilation
Hi allI had my AVR done in May this year, initially I had issues with heart rate jumping around 147. My medications were Bisoprolol 7.5 mg along with standard water tablets and blood thinners.Couple of months after the procedure I had to go A&E for this heart rate procedure but I was either given digoxin
Hi allI had my AVR done in May this year, initially I had issues with heart rate jumping around 147. My medications were Bisoprolol 7.5 mg along with standard water tablets and blood thinners.Couple of months after the procedure I had to go A&E for this heart rate procedure but I was either given digoxin
Devaprinters
in
Arrhythmia Alliance
2 years ago
Curcumin (Theracurmin) Improves Mild Cognitive Impairment and Memory - A Randomized Clinical Trial
 This is a remarkable study of the effects of a highly bioavailable form of Curcumin, "Theracurmin", on memory in non-demented aging adults, including those diagnosed with MCI, Mild Cognitive Impairment. What we call "Chemo-Brain" is a form of MCI resulting from cancer treatments including chemotherapy
 This is a remarkable study of the effects of a highly bioavailable form of Curcumin, "Theracurmin", on memory in non-demented aging adults, including those diagnosed with MCI, Mild Cognitive Impairment. What we call "Chemo-Brain" is a form of MCI resulting from cancer treatments including chemotherapy
MateoBeach
in
Fight Prostate Cancer
2 years ago
After High Intensity Interval Exercise, fT4/ fT3 up from 'normal', 12 hours later both down from 'normal'. Both return to 'normal' by 72hrs
Interesting study discussing the effects of high intensity interval training on : conversion of T4 to T3 . conversion of T4 to rT3 . and CORTISOL. ~ Study is done on healthy fit subjects, so obviously we must assume their healthy functioning thyroid gland also had some involvement in proceedings
Interesting study discussing the effects of high intensity interval training on : conversion of T4 to T3 . conversion of T4 to rT3 . and CORTISOL. ~ Study is done on healthy fit subjects, so obviously we must assume their healthy functioning thyroid gland also had some involvement in proceedings
tattybogle
in
Thyroid UK
2 years ago
Living Cell Technologies announces continued progress on its third clinical trial to assess NTCELL
Living Cell Technologies announces continued progress on its third clinical trial to assess NTCELL in people with #Parkinsons (in collaboration with Nzeno) http://www.irasia.com/listco/au/lct/halfyr/2023/intpress.htm
Living Cell Technologies announces continued progress on its third clinical trial to assess NTCELL in people with #Parkinsons (in collaboration with Nzeno) http://www.irasia.com/listco/au/lct/halfyr/2023/intpress.htm
Hidden
in
Cure Parkinson's
2 years ago
Inhibikase Therapeutics Announces FDA has Lifted the Full Clinical Hold on IkT-148009 in Parkinson's Disease
https://www.inhibikase.com/news/press-releases/detail/72/inhibikase-therapeutics-announces-fda-has-lifted-the-full "We are grateful for the expeditious review by the FDA of our response to the Clinical Hold on IkT-148009 in PD," stated Milton H. Werner, Ph.D., President and Chief Executive Officer
https://www.inhibikase.com/news/press-releases/detail/72/inhibikase-therapeutics-announces-fda-has-lifted-the-full "We are grateful for the expeditious review by the FDA of our response to the Clinical Hold on IkT-148009 in PD," stated Milton H. Werner, Ph.D., President and Chief Executive Officer
Hidden
in
Cure Parkinson's
2 years ago
Beware of ultrasound treatment for Parkinson’s disease!
I participated in a clinical trial of focused ultrasound treatment for Parkinson’s disease. I was treated at Stanford University hospital. 15 participants were given the treatment, but I was one of the five participants assigned to the placebo group. The assignment was blinded.to participants. In the
I participated in a clinical trial of focused ultrasound treatment for Parkinson’s disease. I was treated at Stanford University hospital. 15 participants were given the treatment, but I was one of the five participants assigned to the placebo group. The assignment was blinded.to participants. In the
Pitchfixer
in
Cure Parkinson's
2 years ago
Annovis Bio Clinical Trials Update . . .
Strong interest being shown in Annovis Bio Parkinsons clinical trials https://stocks.apple.com/A5Vy9P2FBSVmyh_y-Zvz_GQ
Strong interest being shown in Annovis Bio Parkinsons clinical trials https://stocks.apple.com/A5Vy9P2FBSVmyh_y-Zvz_GQ
redhawk1
in
Cure Parkinson's
2 years ago
Clinical trials for AML
Hi. Since I had a abmt in July I have been visiting the hospital 3 times a week. I have become friendly with a couple and the wife who has aml is always needing platelets or something. Her transplant has been put on hold because of her blood levels and sadly their consultant is not being very informative
Hi. Since I had a abmt in July I have been visiting the hospital 3 times a week. I have become friendly with a couple and the wife who has aml is always needing platelets or something. Her transplant has been put on hold because of her blood levels and sadly their consultant is not being very informative
Kraskie1915
in
Leukaemia Support
2 years ago
Idea for a Clinical Trial : High Dose Thiamine (HDT—B1)
Idea for a Clinical Trial: It is difficult to set up a High Dose Thiamine (HDT—B1) Clinical Trail because dose is variable, unique and the
protocol can take more than six months
(added cost)—So how about a trial where People with Parkinson (PwP) who are successful on a HDT dose, be split into
Idea for a Clinical Trial: It is difficult to set up a High Dose Thiamine (HDT—B1) Clinical Trail because dose is variable, unique and the
protocol can take more than six months
(added cost)—So how about a trial where People with Parkinson (PwP) who are successful on a HDT dose, be split into
Gcf51
in
Cure Parkinson's
2 years ago
So now I'm a bit scared.
I posted about deciding to do an ablation consult the other day, I have that scheduled for Dec 30th. Well that evening the 23rd I had a new arrhythmia show up. I sent it to Kardia clinician review, and they said it was ventricular tachycardia. The sort of rhythm that when sustained can lead to ventricular
I posted about deciding to do an ablation consult the other day, I have that scheduled for Dec 30th. Well that evening the 23rd I had a new arrhythmia show up. I sent it to Kardia clinician review, and they said it was ventricular tachycardia. The sort of rhythm that when sustained can lead to ventricular
ChasMartin
in
AF Association
2 years ago
Treatment Resistant Major Depressive Disorder: I am proof that there is hope.
I have been horrifically plagued by MDD for over a decade. In my journey I have tried literally every therapy and intervention possible including multiple medications, every psychotherapy possible, residential treatment programs, partial hospitalization plans, intensive outreach programs, TMS, ECT, ketamine
I have been horrifically plagued by MDD for over a decade. In my journey I have tried literally every therapy and intervention possible including multiple medications, every psychotherapy possible, residential treatment programs, partial hospitalization plans, intensive outreach programs, TMS, ECT, ketamine
jnelson66
in
Major Depressive Disorder (MDD) Support
2 years ago
Afib worse than before ablation
I had the most glorious day in 3 years on the 4th day after my first ablation, which the doc said went great. The first three days were tougher because I had a sort throat, fever, then a migraine. But on day 4 I felt incredible…until about 9:30pm when my watch told me I was in afib again. And then
I had the most glorious day in 3 years on the 4th day after my first ablation, which the doc said went great. The first three days were tougher because I had a sort throat, fever, then a migraine. But on day 4 I felt incredible…until about 9:30pm when my watch told me I was in afib again. And then
UnhappyAF
in
AF Association
2 years ago
”Aggressive” AF
Does anybody on here have experience or encouraging stories about Atrial Fibrillation especially the aggressive kind. I'm 43 and diagnosed with AF in March '21. I've had a cardioversion, 2 ablations in the upper chamber and 1 ablation in a lower chamber. The last ablation was in June then in July, I
Does anybody on here have experience or encouraging stories about Atrial Fibrillation especially the aggressive kind. I'm 43 and diagnosed with AF in March '21. I've had a cardioversion, 2 ablations in the upper chamber and 1 ablation in a lower chamber. The last ablation was in June then in July, I
BeeBee79
in
AF Association
2 years ago
Any ideas/stories about treating PAC’s??
Had ablation in May of this year for lone AFib. Structurally normal heart. Had mild runs of PACs prior to the procedure that would come and go. Now going on 7 months after procedure and they are more bothersome than the AFib was. Last for hours and/or days on end. It’s really wearing me down. I’ve tried
Had ablation in May of this year for lone AFib. Structurally normal heart. Had mild runs of PACs prior to the procedure that would come and go. Now going on 7 months after procedure and they are more bothersome than the AFib was. Last for hours and/or days on end. It’s really wearing me down. I’ve tried
Golf1515
in
AF Association
2 years ago
A-Flutter Ablation Success
How many have had an a-flutter ablation and it lasted? My doctor made it sound like its one and done for a long time to come but the more I read, the more it makes me think it's just temporary and a way of life to have to keep going in or then possibly have to get another one for Afib very soon after
How many have had an a-flutter ablation and it lasted? My doctor made it sound like its one and done for a long time to come but the more I read, the more it makes me think it's just temporary and a way of life to have to keep going in or then possibly have to get another one for Afib very soon after
Aflutter1
in
AF Association
2 years ago
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