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Choose Capivasertib or 177Lu-PSMA-617 clinical trial or stick with ADT + radiation?
Hi Folks, My PSA is up to 49 from 24 last summer. After bone scan, CT scan indicated 3 sites of mets (2 on pelvis, 1 on L5, overall “low volume”). Otherwise feeling great, working out most days. 58. I was finally able to get in this month to see a Medical Oncologist. Starting on ADT next week. Meeting
Hi Folks, My PSA is up to 49 from 24 last summer. After bone scan, CT scan indicated 3 sites of mets (2 on pelvis, 1 on L5, overall “low volume”). Otherwise feeling great, working out most days. 58. I was finally able to get in this month to see a Medical Oncologist. Starting on ADT next week. Meeting
LongTimeRunning
in
Advanced Prostate Cancer
1 year ago
had Flutter Cardioversion…stressing
had CV 2 days ago then ate dinner last night too quickly, had a sense of panic Some pounding in my chest, breathing hard, thought I’d reverted back and couldn’t relax for 2 hours. My Apple Watch said sinus. Prior to CV apple watch said sinus when I was confirmed in Atrial Flutter at hospital prior to
had CV 2 days ago then ate dinner last night too quickly, had a sense of panic Some pounding in my chest, breathing hard, thought I’d reverted back and couldn’t relax for 2 hours. My Apple Watch said sinus. Prior to CV apple watch said sinus when I was confirmed in Atrial Flutter at hospital prior to
OzJames
in
Atrial Fibrillation Support
2 years ago
cardiac ablation
my cardiologist had recommended an ablation a year ago but I choose to wait. I’ve had very few episodes on Flecinide and Eliquis. Now he’s saying my heart rate is getting too low and we need to revisit having the ablation. I’m looking for feedback from those who have had the procedure.
my cardiologist had recommended an ablation a year ago but I choose to wait. I’ve had very few episodes on Flecinide and Eliquis. Now he’s saying my heart rate is getting too low and we need to revisit having the ablation. I’m looking for feedback from those who have had the procedure.
Rals52
in
AF Association
2 years ago
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Back in hospital with fast atrial flutter.
I’m in my local hospital with atrial flutter (and some good old AF) at about 150 bpm (following a bypass about a week ago). This seems to switch on when I sit up in bed or get out of bed. Blood pressure is low at 94/59. It’s too dangerous to cardiovert at the moment. They’ve increased the Bisoprolol
I’m in my local hospital with atrial flutter (and some good old AF) at about 150 bpm (following a bypass about a week ago). This seems to switch on when I sit up in bed or get out of bed. Blood pressure is low at 94/59. It’s too dangerous to cardiovert at the moment. They’ve increased the Bisoprolol
Samazeuilh2
in
Atrial Fibrillation Support
2 years ago
Thyroid Hormones and Cardiac Arrhythmia
Johannes Wolfgang Dietrich says: [i]Our book "#Thyroid Hormones and Cardiac #Arrhythmia", including the articles from our Research Topic at Frontiers, is ready.[/i] This new book is freely accessible and downloadable as a PDF or in EPUB format. I've downloaded it but not yet opened it! Topic editor
Johannes Wolfgang Dietrich says: [i]Our book "#Thyroid Hormones and Cardiac #Arrhythmia", including the articles from our Research Topic at Frontiers, is ready.[/i] This new book is freely accessible and downloadable as a PDF or in EPUB format. I've downloaded it but not yet opened it! Topic editor
helvella
Thyroid UK
in
Thyroid UK
2 years ago
New Here — Most Recent Arrhythmia
Hi, all — I initially posted this to the Afib Forum but just found this group, which seems more appropriate. I was experiencing episodes of tachycardia sometimes lasting up to a half hour or so. Being a non-cardiologist, my first thought was Afib and, indeed, that’s what my Apple Watch said. I ended
Hi, all — I initially posted this to the Afib Forum but just found this group, which seems more appropriate. I was experiencing episodes of tachycardia sometimes lasting up to a half hour or so. Being a non-cardiologist, my first thought was Afib and, indeed, that’s what my Apple Watch said. I ended
wdstk51
in
Arrhythmia Alliance
2 years ago
Dofitilide without Afib??
Hi, all — not sure this is the right place to be, since it doesn’t really appear that I have AFib. I was experiencing episodes of tachycardia sometimes lasting up to a half hour or so. Being a non-cardiologist, my first thought was Afib and, indeed, that’s what my Apple Watch said. I ended up going
Hi, all — not sure this is the right place to be, since it doesn’t really appear that I have AFib. I was experiencing episodes of tachycardia sometimes lasting up to a half hour or so. Being a non-cardiologist, my first thought was Afib and, indeed, that’s what my Apple Watch said. I ended up going
wdstk51
in
AF Association
2 years ago
Terbium-161 instead of Lutetium-177
Here's an intriguing abstract from the ASCO conference that is going on right now (February 2023). Hofman and company in Australia are starting a clinical trial (NCT05521412) to evaluate using Tb-161 instead of Lu-177 linked to the PSMA-I&T targeting ligand. The hope is that the shorter range and higher
Here's an intriguing abstract from the ASCO conference that is going on right now (February 2023). Hofman and company in Australia are starting a clinical trial (NCT05521412) to evaluate using Tb-161 instead of Lu-177 linked to the PSMA-I&T targeting ligand. The hope is that the shorter range and higher
TeleGuy
in
Advanced Prostate Cancer
2 years ago
here’s my Christmas carol
🎤We 3 Kings of AF are; Bearing ectopics we traverse afar; Chest and neck, eyes and forehead ; Following AF route, oooohhhh; Star of AF, star of night , star with awful loss of sight , Palpitations leading , still proceeding , Guide us on to SINUS RHYTHM (🤞🤞🤞) 🎼🎹 Merry Christmas fellow
🎤We 3 Kings of AF are; Bearing ectopics we traverse afar; Chest and neck, eyes and forehead ; Following AF route, oooohhhh; Star of AF, star of night , star with awful loss of sight , Palpitations leading , still proceeding , Guide us on to SINUS RHYTHM (🤞🤞🤞) 🎼🎹 Merry Christmas fellow
Ossie7
in
Atrial Fibrillation Support
2 years ago
Is Afib linked to anxiety ?
Hi HU'ers. This article discusses the similarity between afib and anxiety. The conclusion is interesting. [i]'Although chronic stress can affect your cardiovascular health, there isn’t enough evidence to suggest that anxiety causes AFib'[/i] I don't entirely agree with that but let's agree to disagree
Hi HU'ers. This article discusses the similarity between afib and anxiety. The conclusion is interesting. [i]'Although chronic stress can affect your cardiovascular health, there isn’t enough evidence to suggest that anxiety causes AFib'[/i] I don't entirely agree with that but let's agree to disagree
Paulbounce
in
Atrial Fibrillation Support
2 years ago
177LU-DTPA-SC16 attaching DLL3 for neuroendocrine cancer
25% of pCA develop into neuroendocrine variant. Research show good preclinical results. Has anyone information of a clinical trial at MSKCC using SC16 as a monoclonal antibody? https://pubmed.ncbi.nlm.nih.gov/35759660/
25% of pCA develop into neuroendocrine variant. Research show good preclinical results. Has anyone information of a clinical trial at MSKCC using SC16 as a monoclonal antibody? https://pubmed.ncbi.nlm.nih.gov/35759660/
Hidden
in
Advanced Prostate Cancer
2 years ago
📚 Research 101: Who can take part in a clinical trial?
All clinical trials have guidelines about who can participate. Before joining a clinical trial, a participant must qualify for the study. The factors that allow someone to participate in a clinical trial are called "inclusion criteria" and those that disallow someone from participating are called "exclusion
All clinical trials have guidelines about who can participate. Before joining a clinical trial, a participant must qualify for the study. The factors that allow someone to participate in a clinical trial are called "inclusion criteria" and those that disallow someone from participating are called "exclusion
AnnaHU
HealthUnlocked
in
Research Opportunities
2 years ago
Newby wondering what medicine to take for sickness and diarrhoea?
Hello everyone 🤗, this is my first proper post after dipping in and out to read your chats which I have found invaluable to settle my nerves somewhat after being diagnosed with Afib. However, I’m suffering with sickness and diarrhoea and am aware that while on the afib drugs you have to be careful what
Hello everyone 🤗, this is my first proper post after dipping in and out to read your chats which I have found invaluable to settle my nerves somewhat after being diagnosed with Afib. However, I’m suffering with sickness and diarrhoea and am aware that while on the afib drugs you have to be careful what
Ailsablue
in
AF Association
2 years ago
Afib Wearables, capturing data for your EP and a helpful tool.
Thought I would give an update as to my personal study of my AF. For those that have not been following my posts, I consciously decided not to take medications for my AF so I could study the beast by trying alternatives to medications. One of my earliest thoughts was to set up a citizen science website
Thought I would give an update as to my personal study of my AF. For those that have not been following my posts, I consciously decided not to take medications for my AF so I could study the beast by trying alternatives to medications. One of my earliest thoughts was to set up a citizen science website
OzRob
in
Atrial Fibrillation Support
2 years ago
Focal Ablation doesn't work (again)
Cryo joins HIFU, FLA, and IRE as substandard focal thermoablation therapies. Aker et al. reported (below) that on biopsy 18 months post-treatment, 35% still had clinically significant prostate cancer (only 46% had no prostate cancer), and that neither MRI nor PSA were good indicators of treatment failure
Cryo joins HIFU, FLA, and IRE as substandard focal thermoablation therapies. Aker et al. reported (below) that on biopsy 18 months post-treatment, 35% still had clinically significant prostate cancer (only 46% had no prostate cancer), and that neither MRI nor PSA were good indicators of treatment failure
Tall_Allen
in
Prostate Cancer Network
2 years ago
Ambroxol
Would anyone share if you have participated in a clinical trial using the drug Ambroxol for PD? There have been several clinical trials which have published encouraging resusts, mostly in the UK. I am not formally in a trial but have been duplicating the dosage for about 12 months. My experience is favorable
Would anyone share if you have participated in a clinical trial using the drug Ambroxol for PD? There have been several clinical trials which have published encouraging resusts, mostly in the UK. I am not formally in a trial but have been duplicating the dosage for about 12 months. My experience is favorable
Badmouth
in
Cure Parkinson's
2 years ago
Aching feet at night
I’ve been taking Carvedilol for 9 months after AFIB . Had Cardioversion and Ablation but still have occasional AFIB. Now experiencing pain in my feet at night. Had anyone had the same issues and found relief?
I’ve been taking Carvedilol for 9 months after AFIB . Had Cardioversion and Ablation but still have occasional AFIB. Now experiencing pain in my feet at night. Had anyone had the same issues and found relief?
1Golf
in
AF Association
2 years ago
AF and now coronary artery disease at 47. I recently had a CT angiogram and the results aren’t great. Back to being scared and worried.
So I first came on this forum with my Afib diagnosis and was terrified and depressed about the diagnosis and medications. I had good news from my echocardiogram as I had no damage at all. The last hurdle was a CT angiogram sadly I’ve not made it so well past this hurdle. I’m absolutely gutted to be honest
So I first came on this forum with my Afib diagnosis and was terrified and depressed about the diagnosis and medications. I had good news from my echocardiogram as I had no damage at all. The last hurdle was a CT angiogram sadly I’ve not made it so well past this hurdle. I’m absolutely gutted to be honest
Dadtoalad23
in
AF Association
2 years ago
ANY ADVICE
Hi everyone I have been AF free for nearly a year now. I have been taking 75 mg flecainide morning and night half of 125mg Bisoprolol in the morning, Apixaban and 20 mg Tamoxifen. Everything has been great. However in the past week I wake up every morning and my lips are stinging and cracked and
Hi everyone I have been AF free for nearly a year now. I have been taking 75 mg flecainide morning and night half of 125mg Bisoprolol in the morning, Apixaban and 20 mg Tamoxifen. Everything has been great. However in the past week I wake up every morning and my lips are stinging and cracked and
SilverliningsForNow
in
AF Association
2 years ago
PIP advice please
hi all some of you know my story but I’ve had PAF for 29 years about 8 times in that period. I went back in AF in August and went on regime of Flecainide, Metropolol and Apixiban. Decided to do Cardioversion end of September after being on drugs for a month. Went off all drugs after a few weeks told
hi all some of you know my story but I’ve had PAF for 29 years about 8 times in that period. I went back in AF in August and went on regime of Flecainide, Metropolol and Apixiban. Decided to do Cardioversion end of September after being on drugs for a month. Went off all drugs after a few weeks told
OzJames
in
Atrial Fibrillation Support
2 years ago
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