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Atezolizumab
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New advances in treating non-small cell lung cancer
The immunotherapy drug
atezolizumab
also won FDA approval in May 2020 for improvement in survival over standard chemotherapy for many patients with newly diagnosed NSCLC, based on research from Yale Cancer Center and Smilow Cancer Hospital.
The immunotherapy drug
atezolizumab
also won FDA approval in May 2020 for improvement in survival over standard chemotherapy for many patients with newly diagnosed NSCLC, based on research from Yale Cancer Center and Smilow Cancer Hospital.
2greys
in
Lung Conditions Community Forum
3 years ago
Trial Involving Cabozantinib
Hi everyone, Dad has been informed he may be potentially eligible for a trial involving cabozantinib and
atezolizumab
. Has anybody had any dealings with this and if so, did it seem effective? Many thanks as always!
Hi everyone, Dad has been informed he may be potentially eligible for a trial involving cabozantinib and
atezolizumab
. Has anybody had any dealings with this and if so, did it seem effective? Many thanks as always!
Hillwalker87
in
Advanced Prostate Cancer
3 years ago
Immunotherapy Clinical Trial or Olaparib (Lynparza)?
We've been offered two options: 1. a trial of
atezolizumab
+ cabozantinib - an immunotherapy treatment that seems to be promising in Breast Cancer. But, if he is put into the control group, he'd receive enzalutamide (another ADT drug). 2.
We've been offered two options: 1. a trial of
atezolizumab
+ cabozantinib - an immunotherapy treatment that seems to be promising in Breast Cancer. But, if he is put into the control group, he'd receive enzalutamide (another ADT drug). 2.
PCdaughte
in
Advanced Prostate Cancer
3 years ago
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Does anyone have experience with Immunotherapy Atezolizumab?
Does anyone have experience that they can share with an immunotherapy called
Atezolizumab
please? I start this as my next treatment option next week. Wishing you all my best.
Does anyone have experience that they can share with an immunotherapy called
Atezolizumab
please? I start this as my next treatment option next week. Wishing you all my best.
Seagu11s
in
The Roy Castle Lung Cancer Foundation
3 years ago
New cancer treatment
The consultant advice me to use the new drug
atezolizumab
. After being told that I have 6 months to live I have been able to live a normal life for 2 years and 5 months. It is harmless and very minor side effects if any. I hope more people could receive this wonderful creation
The consultant advice me to use the new drug
atezolizumab
. After being told that I have 6 months to live I have been able to live a normal life for 2 years and 5 months. It is harmless and very minor side effects if any. I hope more people could receive this wonderful creation
Imasurvivor7
in
Lung Cancer Support
3 years ago
Lung Cancer: LCMC3: Neoadjuvant atezolizumab safe, meets primary endpoint of pathologic response rate.
Atezolizumab
is a monoclonal antibody that was approved by the US Food and Drug Administration in 2020 for the first-line treatment of adult patients with metastatic NSCLC. https://www.iaslc.org/iaslc-news/press-release/lcmc3-neoadjuvant-
atezolizumab
-safe-meets-primary-endpoint-pathologic
Atezolizumab
is a monoclonal antibody that was approved by the US Food and Drug Administration in 2020 for the first-line treatment of adult patients with metastatic NSCLC. https://www.iaslc.org/iaslc-news/press-release/lcmc3-neoadjuvant-
atezolizumab
-safe-meets-primary-endpoint-pathologic
2greys
in
Lung Conditions Community Forum
4 years ago
Quick Update
Oddly, for such an aggressive cancer, it actually has a low mutational burden which explains why the
atezolizumab
didn't work. As I understand it, my cancer isn't different enough from my healthy tissue for my immune system to care.
Oddly, for such an aggressive cancer, it actually has a low mutational burden which explains why the
atezolizumab
didn't work. As I understand it, my cancer isn't different enough from my healthy tissue for my immune system to care.
tom67inMA
in
Advanced Prostate Cancer
4 years ago
Atezolizumab
The plan and probably my last chance is for
Atezolizumab
immunotherapy which I start next week. I thought it would be Keytruda but he said the above was better for my circumstances. Does anyone have any positive results to the above treatment please or experience of having this drug.
The plan and probably my last chance is for
Atezolizumab
immunotherapy which I start next week. I thought it would be Keytruda but he said the above was better for my circumstances. Does anyone have any positive results to the above treatment please or experience of having this drug.
Mulino
in
The Roy Castle Lung Cancer Foundation
4 years ago
Freaking out over latest blood test results
My body has been beat up by 9 cycles of chemotherapy so far this year, not to mention
atezolizumab
which faield. I really was hoping for some form of remission to allow my body to recover and get healthy again before having to continue the fight.
My body has been beat up by 9 cycles of chemotherapy so far this year, not to mention
atezolizumab
which faield. I really was hoping for some form of remission to allow my body to recover and get healthy again before having to continue the fight.
tom67inMA
in
Advanced Prostate Cancer
4 years ago
Not a candidate for the CAR-T trial. Should I pursue cabozantinib here in the USA or look abroad for LU-177?
The Mayo Clinic has accepted me to get either cabozantinib (XL184) alone or in combination with
atezolizumab
(immunotherapy). Cabozantinib is an oral agent which is great and is FDA approved for medullary thyroid cancer. This is a phase 2 study.
The Mayo Clinic has accepted me to get either cabozantinib (XL184) alone or in combination with
atezolizumab
(immunotherapy). Cabozantinib is an oral agent which is great and is FDA approved for medullary thyroid cancer. This is a phase 2 study.
Cleodman
in
Advanced Prostate Cancer
4 years ago
High PSA with Mets in Check
I’ve been on a clinical trial of a combo of Cabozantinib and
Atezolizumab
for three months now. It’s a combination of pill and infusion. My Mets that involve my lungs, liver and lymph nodes are staying in check. But my PSA climbs 20 spots every three weeks of my treatment.
I’ve been on a clinical trial of a combo of Cabozantinib and
Atezolizumab
for three months now. It’s a combination of pill and infusion. My Mets that involve my lungs, liver and lymph nodes are staying in check. But my PSA climbs 20 spots every three weeks of my treatment.
RalphieJr64
in
Advanced Prostate Cancer
4 years ago
I Can Do an Oil Change
In other news, I completed chemo back in June, finished radiation in July, and continue on
Atezolizumab
, Lupron, Abiraterone, and Xgeva. I'm finally beginning to see glimpses of improving health as I recover from the chemo and radiation.
In other news, I completed chemo back in June, finished radiation in July, and continue on
Atezolizumab
, Lupron, Abiraterone, and Xgeva. I'm finally beginning to see glimpses of improving health as I recover from the chemo and radiation.
tom67inMA
in
Advanced Prostate Cancer
4 years ago
Update on insanity
Atezolizumab
- Vemurafinib - Cobimetinib. Ryan did not fair well on a dual therapy, so I’m not sure if that will be the course of action. Definitely has to be discussed. Once the bowel heals and functions correctly he will be able to eat without restrictions and go back to normal life.
Atezolizumab
- Vemurafinib - Cobimetinib. Ryan did not fair well on a dual therapy, so I’m not sure if that will be the course of action. Definitely has to be discussed. Once the bowel heals and functions correctly he will be able to eat without restrictions and go back to normal life.
kellyOd
in
Melanoma Caregivers
4 years ago
IMbrave050 Clinical Trial currently recruiting
This study will compare the effects, good or bad, of
atezolizumab
plus bevacizumab versus active surveillance (not receiving any study treatment) on patients with completely resected or ablated HCC who are at high risk for disease recurrence Patients will be put into two groups or Arms of the study:
This study will compare the effects, good or bad, of
atezolizumab
plus bevacizumab versus active surveillance (not receiving any study treatment) on patients with completely resected or ablated HCC who are at high risk for disease recurrence Patients will be put into two groups or Arms of the study:
AndreaWilson_Founder
Caregiver
in
Blue Faery Liver Cancer
4 years ago
FDA Approves Tecentriq for First-Line Treatment of Metastatic NSCLC with High PD-L1 Expression
Tecentriq (
atezolizumab
) being available as a first line immunotherapy option for NSCLC gives patients more options for first line treatments than ever before.
Tecentriq (
atezolizumab
) being available as a first line immunotherapy option for NSCLC gives patients more options for first line treatments than ever before.
Miranda_GO2
Partner
in
Lung Cancer Support
4 years ago
After two years, My trial has now stopped working
My MO wants to start chemo again or another clinical trial combo of Cabozantinib-
Atezolizumab
. I wish they would come up with easier names of these drugs. I have to be off my last trial for four weeks to start this new adventure. The side effects like my last trial are debilitating.
My MO wants to start chemo again or another clinical trial combo of Cabozantinib-
Atezolizumab
. I wish they would come up with easier names of these drugs. I have to be off my last trial for four weeks to start this new adventure. The side effects like my last trial are debilitating.
RalphieJr64
in
Advanced Prostate Cancer
4 years ago
A Phase III trial comparing Atezolizumab with Enzalutamide vs Enzalutamide alone in patients with metastatic CRPC
[1] Bottom line: no add-on value or synergy for
Atezolizumab
(a checkpoint inhibitor) with Enzalutamide. "Patients treated with
atezolizumab
(Tecentriq) and enzalutamide (Xtandi) had a median OS of 15.2 months as compared with 16.6 months for single-agent enzalutamide.
[1] Bottom line: no add-on value or synergy for
Atezolizumab
(a checkpoint inhibitor) with Enzalutamide. "Patients treated with
atezolizumab
(Tecentriq) and enzalutamide (Xtandi) had a median OS of 15.2 months as compared with 16.6 months for single-agent enzalutamide.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Immunotherapy and Blood Counts
Part of my cocktail includes
Atezolizumab
which is an immunotherpy agent. I found my blood counts for the last two cycles interesting, and thought I'd share to see if anybody else has seen anything similar or has comments to add.
Part of my cocktail includes
Atezolizumab
which is an immunotherpy agent. I found my blood counts for the last two cycles interesting, and thought I'd share to see if anybody else has seen anything similar or has comments to add.
tom67inMA
in
Advanced Prostate Cancer
4 years ago
Seeking wisdom from those of you that have "been there done that"
I had 12 consecutive weeks of Ptaxil, Carboplatin and either a placebo or
Atezolizumab
(pretty sure it's the
Atezolizumab
). I just started my 4 dose - 2nd round of Doxorubicin, Cyclophosphamide and placebo/
atezolizumab
2 weeks ago....Lord, that was a rough ride for 7 days after!
I had 12 consecutive weeks of Ptaxil, Carboplatin and either a placebo or
Atezolizumab
(pretty sure it's the
Atezolizumab
). I just started my 4 dose - 2nd round of Doxorubicin, Cyclophosphamide and placebo/
atezolizumab
2 weeks ago....Lord, that was a rough ride for 7 days after!
Scullerymaid
in
SHARE Breast Cancer Support
4 years ago
Chemotherapy Cycle 3 and a Blog Post
I'm currently on carboplatin, etoposide, and
atezolizumab
for neuroendocrine prostate cancer. Scans done before the third infusion showed shrinkage of the tumors in my bladder and liver. To enhance the side effects, I also got lupron and xgeva injections at the end of the first week.
I'm currently on carboplatin, etoposide, and
atezolizumab
for neuroendocrine prostate cancer. Scans done before the third infusion showed shrinkage of the tumors in my bladder and liver. To enhance the side effects, I also got lupron and xgeva injections at the end of the first week.
tom67inMA
in
Advanced Prostate Cancer
4 years ago
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