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Two updates in the Guidelines for PBC
PRACTICE GUIDANCE Primary biliary cholangitis: 2021 practice guidance update from the American Association for the Study of Liver Diseases Lindor, Keith D.*,1; Bowlus, Christopher L.2; Boyer, James3; Levy, Cynthia4; Mayo, Marlyn5 Author Information Hepatology 75(4):p 1012-1013, April 2022. | DOI
PRACTICE GUIDANCE Primary biliary cholangitis: 2021 practice guidance update from the American Association for the Study of Liver Diseases Lindor, Keith D.*,1; Bowlus, Christopher L.2; Boyer, James3; Levy, Cynthia4; Mayo, Marlyn5 Author Information Hepatology 75(4):p 1012-1013, April 2022. | DOI
DonnaBoll
Administrator
in
PBC Foundation
2 months ago
hepatic Encephalopathy
morning, can anyone advice me about hepatic Encephalopathy ? I have stage 4 liver desease and was feeling so confused last night with things like time and thinking lights were off but were on is this the start of it? Last time I was like this was last march when I had my diagnoses, I take lactose which
morning, can anyone advice me about hepatic Encephalopathy ? I have stage 4 liver desease and was feeling so confused last night with things like time and thinking lights were off but were on is this the start of it? Last time I was like this was last march when I had my diagnoses, I take lactose which
Kingbilly3
in
British Liver Trust
2 months ago
Some good news to start the day: Complete Response in First Patient Ever Treated with 2 Doses of Cu-67 SAR-bisPSMA at 8GBq...6 months
I have already written about this, but then he approached the 6 months mark, so... "The patient remains with undetectable levels of Prostate Specific Antigen (PSA) for almost 6 months, following the administration of the second dose of 67Cu-SAR-bisPSMA. PSA is a marker used to assess clinical response
I have already written about this, but then he approached the 6 months mark, so... "The patient remains with undetectable levels of Prostate Specific Antigen (PSA) for almost 6 months, following the administration of the second dose of 67Cu-SAR-bisPSMA. PSA is a marker used to assess clinical response
Maxone73
in
Advanced Prostate Cancer
2 months ago
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Lixisenatide as a treatment for early Parkinson’s disease progression
In this randomized controlled trial, lixisenatide reduced motor disability progression in Parkinson’s patients. 2. Individuals in the lixisenatide group experienced greater gastrointestinal side effects rates than individuals in the placebo group. Evidence Rating Level: 1 (Excellent) https:/
In this randomized controlled trial, lixisenatide reduced motor disability progression in Parkinson’s patients. 2. Individuals in the lixisenatide group experienced greater gastrointestinal side effects rates than individuals in the placebo group. Evidence Rating Level: 1 (Excellent) https:/
Farooqji
in
Cure Parkinson's
2 months ago
So the odds we all read about... are they true?
When my husband (age 52) was diagnosed with metastatic prostate cancer two and a half years ago, he was told the outlook was "grim." Everything we read told us once it moves to the bone (his has) then you're looking at months, not years, of life left. He had TEMPUS done, which was basically the oncologist
When my husband (age 52) was diagnosed with metastatic prostate cancer two and a half years ago, he was told the outlook was "grim." Everything we read told us once it moves to the bone (his has) then you're looking at months, not years, of life left. He had TEMPUS done, which was basically the oncologist
Anatalya
in
Advanced Prostate Cancer
2 months ago
PSA Nadir 6 Months After Primary RT Correlates With Prostate Cancer Outcomes — Or does it?, MedPage Today May 22, 2024
[i]This article from MedPage Today is reproduced in full along with the link to the full access editorial comment is also provided. However, it has numerous hyperlinks to the the research cited within. The link to the MedPage article provides those links. [/i] [i]* * *[/i]
PSA Nadir 6 Months After
[i]This article from MedPage Today is reproduced in full along with the link to the full access editorial comment is also provided. However, it has numerous hyperlinks to the the research cited within. The link to the MedPage article provides those links. [/i] [i]* * *[/i]
PSA Nadir 6 Months After
cujoe
in
Fight Prostate Cancer
2 months ago
Request for Input
Before I leave this wonderful group I'd like to pick your individual/collective brains. Since it's too late to help my husband, I'm looking for info that I can pass on to my son and 6 grandsons so they might better understand this awful cancer should they ever get it. I'm also providing a bit more info
Before I leave this wonderful group I'd like to pick your individual/collective brains. Since it's too late to help my husband, I'm looking for info that I can pass on to my son and 6 grandsons so they might better understand this awful cancer should they ever get it. I'm also providing a bit more info
Shamrock46
in
Advanced Prostate Cancer
2 months ago
Almost ready for phase 1: JHU083 (or JHU-083) a selective glutamine metabolism blocker
"The drug, JHU083, is a type of molecule called a prodrug that cells inside the body convert into an active drug. Specifically, JHU083 can only be turned into its active, glutamine-blocking form inside the tumor, preventing it from causing harmful side effects elsewhere in the body. " We all know that
"The drug, JHU083, is a type of molecule called a prodrug that cells inside the body convert into an active drug. Specifically, JHU083 can only be turned into its active, glutamine-blocking form inside the tumor, preventing it from causing harmful side effects elsewhere in the body. " We all know that
Maxone73
in
Advanced Prostate Cancer
2 months ago
Robotic Ureteral Reimplantation
Have any of you had this surgery? How did it turn out? My right ureter has a partial blockage that is believed to be radiation damage from my prostate cancer radiation treatments five years ago. The ureter is very narrow near the bladder, and urine flow is restricted. A surgeon at University of Chicago
Have any of you had this surgery? How did it turn out? My right ureter has a partial blockage that is believed to be radiation damage from my prostate cancer radiation treatments five years ago. The ureter is very narrow near the bladder, and urine flow is restricted. A surgeon at University of Chicago
Polaris1
in
Advanced Prostate Cancer
2 months ago
Tested positive for celiac disease today, what next?
I had a gastroscopy in march to test for celiac as i had a very high positive blood test, I received a letter this morning saying that it was positive for celiac and that he is happy to discharge me back to my GP for management of my celiac disease, So my question is what will happen next? Or should
I had a gastroscopy in march to test for celiac as i had a very high positive blood test, I received a letter this morning saying that it was positive for celiac and that he is happy to discharge me back to my GP for management of my celiac disease, So my question is what will happen next? Or should
Mhymer
in
Gluten Free Guerrillas
2 months ago
Anyone been recruited into Pearl study?
Has anyone on here been recruited on to the Pearl study and if so how did they get signed up? Pearl is an acronym of - Prospective Cohort for Early Detection of Liver Cancer The Pearl study aims to recruit 3000 people with liver cirrhosis caused by one of the underlying conditions of HCV, HBV, alcohol-related
Has anyone on here been recruited on to the Pearl study and if so how did they get signed up? Pearl is an acronym of - Prospective Cohort for Early Detection of Liver Cancer The Pearl study aims to recruit 3000 people with liver cirrhosis caused by one of the underlying conditions of HCV, HBV, alcohol-related
Tiger800xrt
in
British Liver Trust
2 months ago
Extreme pain in legs
Sorry for yet another post,My husband has decompensated liver cirrhosis and his legs are extremely swollen and he is at the point of not being able to walk now he's in so much pain he also has pain in his lower back, should he go to hospital? If so does anyone know what they will do?
Sorry for yet another post,My husband has decompensated liver cirrhosis and his legs are extremely swollen and he is at the point of not being able to walk now he's in so much pain he also has pain in his lower back, should he go to hospital? If so does anyone know what they will do?
Hithereeveryone
in
British Liver Trust
2 months ago
Phase 1/2 of TLX592 Targeted Alpha Therapy in Prostate Cancer starting soon - Ac 225
"The approach accelerates blood clearance and reduces bone marrow residence time compared with standard monoclonal antibodies (mAbs), while retaining target selectivity, internalisation and retention." https://www.prnewswire.com/news-releases/telix-completes-proof-of-concept-study-of-tlx592-targeted-alpha-therapy-in-prostate-cancer
"The approach accelerates blood clearance and reduces bone marrow residence time compared with standard monoclonal antibodies (mAbs), while retaining target selectivity, internalisation and retention." https://www.prnewswire.com/news-releases/telix-completes-proof-of-concept-study-of-tlx592-targeted-alpha-therapy-in-prostate-cancer
Maxone73
in
Advanced Prostate Cancer
2 months ago
Psychological and fitness assessment form
Hi, I’m filling in my transplant assessment form for a meeting in a few weeks time and some of the questions seem vague. There is a question regarding how healthy I feel today with a scale from 1 to 10 ( eq5d ). Does this refer to mental, physical or general health ? Also , if you say you feel too
Hi, I’m filling in my transplant assessment form for a meeting in a few weeks time and some of the questions seem vague. There is a question regarding how healthy I feel today with a scale from 1 to 10 ( eq5d ). Does this refer to mental, physical or general health ? Also , if you say you feel too
Bootsforlife
in
British Liver Trust
2 months ago
borderline renal function, my MD cut my Nubeqa in half--thoughts?
Borderline renal function, mets to pelvis, and multiple lymph nodes in lungs, but seen only on PET, not on MRI . age 83
Borderline renal function, mets to pelvis, and multiple lymph nodes in lungs, but seen only on PET, not on MRI . age 83
Sweetjessie
in
Advanced Prostate Cancer
2 months ago
Ped5i/Tadalafil etc as a benefit to SE of ADT?
Tadalafil , etc is prescribed for ED, BPH and PAH (pulmonary arterial hypertension). It is pretty much agreed upon that Tadalafil increases insulin sensitivity thus improving lean body mass, particularly around the gut, improves Testosterone/estrogen relationship and is good for heart and vascular health
Tadalafil , etc is prescribed for ED, BPH and PAH (pulmonary arterial hypertension). It is pretty much agreed upon that Tadalafil increases insulin sensitivity thus improving lean body mass, particularly around the gut, improves Testosterone/estrogen relationship and is good for heart and vascular health
pj1121
in
Advanced Prostate Cancer
2 months ago
UTI Treatment
Can someone please tell me what antibiotic might be best fo a water infection. I'm so worried about a bad reaction since that's what I got with taking Nitrofurantoin.Thank you.
Can someone please tell me what antibiotic might be best fo a water infection. I'm so worried about a bad reaction since that's what I got with taking Nitrofurantoin.Thank you.
3rdNettydoon
in
Pernicious Anaemia Society
2 months ago
THC , CBD
hi During my annual swaree down to South Africa , I came across a health guru, advised Me to try THC , the only problem is I’m about to finish my small bottle , I’ve been putting couple of drops under my tongue when my off period starts after madopar , why are we so stuck up in the uk , with all these
hi During my annual swaree down to South Africa , I came across a health guru, advised Me to try THC , the only problem is I’m about to finish my small bottle , I’ve been putting couple of drops under my tongue when my off period starts after madopar , why are we so stuck up in the uk , with all these
Troongolfer
in
Cure Parkinson's
2 months ago
Kidney stones?
Morning everyone, just wondered if anyone has had kidney stones. I have been experiencing pain in my left groin and lower back and side for a few weeks. It wakes me up at night and l get it intermittently through the day. The doctor thinks it maybe Arthritis and l am getting a xray on Thursday. What
Morning everyone, just wondered if anyone has had kidney stones. I have been experiencing pain in my left groin and lower back and side for a few weeks. It wakes me up at night and l get it intermittently through the day. The doctor thinks it maybe Arthritis and l am getting a xray on Thursday. What
70michael
in
Lung Conditions Community Forum
2 months ago
BLA for Subcutaneous Nivolumab Accepted by the FDA for Advanced/Metastatic Solid Tumors
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
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