Experiences with

Anal fistula

Also last December I had a surgery for a small anal fistula. It healed well, but I think it has returned, so Friday morning I sent an email ago my dr. At the University of Chicago and now I have an appointment on November 11th with the colorectal surgeon that worked on me last December.

Doctor thinks it may be anal fissures or fistula.

Also last December I had a surgery for a small anal fistula. It healed well, but I think it has returned, so Friday morning I sent an email ago my dr. At the University of Chicago and now I have an appointment on November 11th with the colorectal surgeon that worked on me last December.

MedPage Today provides expert commentary on conferences and research on a full range of medical conditions. The following articles on research presented at the recent Genitourinary Cancers Symposium (13-15 Feb) are all worthy of your time. Each provides concise summary commentary and links to all sources

“Finally, after disease progression during enzalutamide, we decided to start a new line of hormone therapy. In fact, considering age, PS, and patient’s will, available therapeutic options were running out, but particularly we trusted a disease’s residual sensitivity to androgen receptor-targeted therapies

Another arrow..... A new Phase 1 study suggests that combining Cabozantinib with Atezolizumab could improve outcomes for patients with metastatic castration-resistant prostate cancer (mCRPC). While overall tumor response rates were similar between monotherapy and combination therapy, patients receiving

With all the limits of a retrospective study (otherwise I might almost become depressed...) A real-world study of 41,379 prostate cancer patients found that GnRH antagonists lead to faster castration resistance than LHRH agonists, with a median time to CRPC of 10.9 vs. 17.3 months (HR 1.40, p=0.02).

Hi all, My specialist has recommended a nerve block with pulsed radiofrequency ablation of pudendal nerve. I have been suffering this for 3 months. My question is, has anyone here undergone pulsed radiofrequency ablation? Was there any flare up of pain ? Or long term flare up of pain? I would

I found this interesting: "Hyperthermia in Combination with Emerging Targeted and Immunotherapies as a New Approach in Cancer Treatment". https://www.mdpi.com/2072-6694/16/3/505 They also mention that it is effective with chemo and RT. This is work being done by a company in Belgium that is

A recent study on batiraxcept, a soluble AXL signaling inhibitor, highlights its potential in suppressing prostate cancer bone metastases. Using patient-derived xenograft models, researchers showed that batiraxcept, alone or in combination with docetaxel or carboplatin, significantly reduced tumor

Or maybe they won't help with it, but we would not care! 😜😜 Repurposing antipsychotic drugs offers a promising, cost-effective approach to cancer treatment. These medications, already tested for safety, could move swiftly into clinical trials and potentially enhance current therapies. First-generation

I just had some blood with my BM. Just some drops in the bowl, nothing on the paper. I'm wondering if this could be from a hemorrhoid (not that I knew I had any). I do suffer from constipation and was straining somewhat. Am a bit worried. Thanks!

Promising approach for multiple tumors (even if in its early stage). RPT04402 is a first-in-class molecular glue that selectively reactivates PP2A, a tumor suppressor enzyme crucial for regulating cell growth. By restoring PP2A activity, this therapy suppresses oncogenic pathways, offering a novel

I am in my 60, was diagnosed with stage 2 prostate cancer, i am going Through hell with biopsy and markers procedure, each times I got bad infection, the last procedure I was hospitalized for a week, send home with midline to have ertapenem antibiotic administer for 14 days! I am considering ivermectin

I would have thought methionine was both too ubiquitous and too important for its restriction to be a valid PCa treatment. "During the time the patient was on methionine restriction alone, effected by a low-methionine diet and o-rMETase, the metastatic prostate cancer did not progress. " https://

Because sometimes it's nice to know the actual outcomes in day to day clinical practice. A retrospective real-world study analyzed the effectiveness of apalutamide (APA) combined with androgen-deprivation therapy (ADT) as a first-line treatment for metastatic hormone-sensitive prostate cancer (mHSPC

The WOMBAT Trial (Working Out M0 Bipolar Androgen Therapy) investigates the efficacy of bipolar androgen therapy (BAT) in extending metastasis-free survival for patients with M0 castration-resistant prostate cancer (CRPC) experiencing rising PSA levels on darolutamide, without visible metastases. This

KPG-121 is an experimental cereblon modulator aimed at metastatic castration-resistant prostate cancer (mCRPC). Early research shows it binds more strongly than lenalidomide to a key immune-regulating protein, potentially boosting anti-cancer effects. In a Phase 1 study of 16 mCRPC patients already taking

Has anyone had an MRI proctogram or similar? I've had ibs for 28 years now and tried so many things to help. Haven't had much help thru the nhs. I now suffer from additional even more difficult to deal with issues in that I get urgency to pass stool, tiny flecks of stool, small stool, frequent toilet

Hi, I have tried gtn and diltiazem creams for a chronic fissure which did not work, has anyone here had laser treatment for a fissure?