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Experiences with
Androgen deprivation therapy (ADT)
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Radiotherapy for prostate local and retroperitoneal nodes
ADT
of lupron and abiraterone has been pretty tolerable so far, almost four months - maybe I got cocky. Started my SBRT 28 fraction 70 Gy radiotherapy four days ago, mild to moderate urinary urgency and some burn started almost immediately. Diarrhea started at night after day four, mild so far.
ADT
of lupron and abiraterone has been pretty tolerable so far, almost four months - maybe I got cocky. Started my SBRT 28 fraction 70 Gy radiotherapy four days ago, mild to moderate urinary urgency and some burn started almost immediately. Diarrhea started at night after day four, mild so far.
pj1121
in
Advanced Prostate Cancer
6 months ago
PSA post Salvage Radiation
He hasn’t been on
ADT
, is that the next step? He’s BRCA2 positive. We’ll also make an appointment with his oncologist . I appreciate any guidance/help on what we should ask/research as I’m quite new to this and, of course, worried. thank you!!
He hasn’t been on
ADT
, is that the next step? He’s BRCA2 positive. We’ll also make an appointment with his oncologist . I appreciate any guidance/help on what we should ask/research as I’m quite new to this and, of course, worried. thank you!!
Silverlings
in
Advanced Prostate Cancer
5 months ago
dilemma ADT duration
Now been on
ADT
(Zoladex) for 10 months (or 8 months adjuvant). There is a suggestion that I stop
ADT
now rather than go to 18-24months given my pre existing extensive polio paralysis.
Now been on
ADT
(Zoladex) for 10 months (or 8 months adjuvant). There is a suggestion that I stop
ADT
now rather than go to 18-24months given my pre existing extensive polio paralysis.
SimMartin
in
Advanced Prostate Cancer
9 months ago
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EBRT - Is it the right thing and what to expect?
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of
ADT
of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84.
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of
ADT
of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84.
JazzMan42
in
Advanced Prostate Cancer
1 month ago
Thoughts on Denosumab in my case
On monthly
ADT
injections, radiation starting soon. ——————- T score interpretation according to the National Osteoporosis Foundation: T-score at or above -1.0 Normal T-score between -1.0 and -2.5 osteopenia T-score at or below -2.5 osteoporosis REGION: L-spine (L1-4): BMD (g/cm2): 1.139 g/cm2
On monthly
ADT
injections, radiation starting soon. ——————- T score interpretation according to the National Osteoporosis Foundation: T-score at or above -1.0 Normal T-score between -1.0 and -2.5 osteopenia T-score at or below -2.5 osteoporosis REGION: L-spine (L1-4): BMD (g/cm2): 1.139 g/cm2
Hope49823
in
Advanced Prostate Cancer
3 months ago
HDR boost Brachytherapy + IMRT
All RO’s I’ve met with want to wait 2-3 months for the
ADT
to do its thing and shrink the primary tumor and lymph nodes before they that radiation start treatment. One RO I met with wants to treat with just IMRT. Another I met with wants to use HDR Brachy boost + IMRT.
All RO’s I’ve met with want to wait 2-3 months for the
ADT
to do its thing and shrink the primary tumor and lymph nodes before they that radiation start treatment. One RO I met with wants to treat with just IMRT. Another I met with wants to use HDR Brachy boost + IMRT.
Cenerus
in
Advanced Prostate Cancer
1 month ago
Time to PSA Nadir is related to progression-free-survival
Cohort:
ADT
monotherapy (No RP or RT), all metastatic patients, median 74 y.o., GS = 8-10, N=419. A cubic spline curve fit matched the data points very well, with a high correlation coefficient, R^2 = 0.944, and a low p = 0.040.
Cohort:
ADT
monotherapy (No RP or RT), all metastatic patients, median 74 y.o., GS = 8-10, N=419. A cubic spline curve fit matched the data points very well, with a high correlation coefficient, R^2 = 0.944, and a low p = 0.040.
janebob99
in
Advanced Prostate Cancer
1 month ago
High-Dose Transdermal Estradiol as ADT
Does anyone have any experience with this? According to my understanding: It's not FDA approved, but used here in the U.S., and all over the rest of the world. It's at least as effective in lowering T to castrate levels. It carries a far more tolerable profile of SEs than LHRH drugs, presumably
Does anyone have any experience with this? According to my understanding: It's not FDA approved, but used here in the U.S., and all over the rest of the world. It's at least as effective in lowering T to castrate levels. It carries a far more tolerable profile of SEs than LHRH drugs, presumably
Horse12888
in
Advanced Prostate Cancer
7 months ago
Lu177 Long Term Survival
Is it easier on the body than
ADT
? Thanks everyone.
Is it easier on the body than
ADT
? Thanks everyone.
NDJIM
in
Advanced Prostate Cancer
9 months ago
Criteria for "my ADT has stopped working and we have to move to another"
Hello - So my third post
ADT
initiation (Lupron+Abi) PSA test is coming up and since it was <.1 six weeks ago, I asked how the criteria of “has stopped working” works -to my Hopkins MO and I got this - “We want to declare a therapy no longer effective when PSA is clearly going up.
Hello - So my third post
ADT
initiation (Lupron+Abi) PSA test is coming up and since it was <.1 six weeks ago, I asked how the criteria of “has stopped working” works -to my Hopkins MO and I got this - “We want to declare a therapy no longer effective when PSA is clearly going up.
jackwfrench
in
Advanced Prostate Cancer
4 months ago
Survey!
So, I and other members can get an idea on how you feel about
vacation(s). Please just answer YES if you think they’re okay, or NO, if you think they’re not.
So, I and other members can get an idea on how you feel about
vacation(s). Please just answer YES if you think they’re okay, or NO, if you think they’re not.
j-o-h-n
in
Advanced Prostate Cancer
6 months ago
Hot Flashes and Veozah
I am 19 months into my 2 years on
ADT
+ Zytiga & P. 6 months into it, I started experiencing severe hot flashes. Severe = Full body sweats, dripping off my brow, palms wet and needing to mop it off my chest or change my shirt. Every 1 -2 hours. I tried 4 antidepressants that didn't work.
I am 19 months into my 2 years on
ADT
+ Zytiga & P. 6 months into it, I started experiencing severe hot flashes. Severe = Full body sweats, dripping off my brow, palms wet and needing to mop it off my chest or change my shirt. Every 1 -2 hours. I tried 4 antidepressants that didn't work.
Huzzah1
in
Advanced Prostate Cancer
4 months ago
question for those who have stopped Lupron after many years of ADT
I have been on Lupron for 8 years with the short-term exception of a high/T clinical trial,( but even during the trial I stayed on Lupron). Anyway I’m undetectable and decided to stop Lupron. 3 months after not getting my shot my T is now a whopping 37. I am curious to hear from some of you who
I have been on Lupron for 8 years with the short-term exception of a high/T clinical trial,( but even during the trial I stayed on Lupron). Anyway I’m undetectable and decided to stop Lupron. 3 months after not getting my shot my T is now a whopping 37. I am curious to hear from some of you who
Chugach
in
Advanced Prostate Cancer
24 days ago
De-escalation
I am working with my own MO on de-escalation so no
ADT
injection for me at the end of September and so am on the Apalutamide monotherapy. ( only been a couple of weeks). Will report my QOL situation plus any change to. My PSA which has been undetectable for 14 months.
I am working with my own MO on de-escalation so no
ADT
injection for me at the end of September and so am on the Apalutamide monotherapy. ( only been a couple of weeks). Will report my QOL situation plus any change to. My PSA which has been undetectable for 14 months.
Brysonal
in
Fight Prostate Cancer
7 months ago
Shoud I be concerned with my PSA rising from .79 to 1.01 in about 10 months?
Diagnosed with prostate cancer in August'18 with PSA of 7.84, Greason score of 7 (4+3) before being treated with SBRT without
ADT
at UCLA in October'18. Reached nadir at .79 after 4.5 years after SBRT treatment.
Diagnosed with prostate cancer in August'18 with PSA of 7.84, Greason score of 7 (4+3) before being treated with SBRT without
ADT
at UCLA in October'18. Reached nadir at .79 after 4.5 years after SBRT treatment.
mike2344
in
Prostate Cancer Network
4 months ago
How long does ADT affect mood swings and anger after stopping treatment ?
Hello, Usually ok but a few outbursts recently.. anger issues upset .. but generally easy going nice person. It’s almost been 2 months since last and final shot and had irrational incident. Anybody else experience challenges after therapy and was wonder when you reached a normal feeling. I generally
Hello, Usually ok but a few outbursts recently.. anger issues upset .. but generally easy going nice person. It’s almost been 2 months since last and final shot and had irrational incident. Anybody else experience challenges after therapy and was wonder when you reached a normal feeling. I generally
Yokohama2023
in
Prostate Cancer Network
29 days ago
Which Estrogen Patch dose to use?
The data set from Smith et. al (2019) is for castrate-resistant prostate cancer men (CRPC), who are not taking
ADT
. Overall, the serum E2 concentration increases as the number of E2 patches used per week (Total weekly E2 dose) increases.
The data set from Smith et. al (2019) is for castrate-resistant prostate cancer men (CRPC), who are not taking
ADT
. Overall, the serum E2 concentration increases as the number of E2 patches used per week (Total weekly E2 dose) increases.
janebob99
in
Prostate Cancer Network
2 months ago
18 vs 24 mos ADT
What have others experienced with
ADT
duration?
What have others experienced with
ADT
duration?
Oceankayaker
in
Advanced Prostate Cancer
10 months ago
BONE DENSITY TEST IS BAD
I see my oncologist next week, and think I need a
ADT
“ vacation “, as I’m also having a lot of brain fog.
I see my oncologist next week, and think I need a
ADT
“ vacation “, as I’m also having a lot of brain fog.
JL1955
in
Advanced Prostate Cancer
4 months ago
Newbie …
So about to start both
ADT
and chemo. Does anyone have experience of this?
So about to start both
ADT
and chemo. Does anyone have experience of this?
Sillyolbugga
in
Advanced Prostate Cancer
3 months ago
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