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My dad’s diagnosis stage 3a adenocarcinoma. Feel 💔

It’s stage 3a adenocarcinoma. Waiting for the treatment plan with the oncologist to start quickly. I feel 💔 Symptoms were ignored by medics last year and someone saw a growth last June in his lung and never told us. I just hope we can get treatment quickly and there’s a positive path ahead.
It’s stage 3a adenocarcinoma. Waiting for the treatment plan with the oncologist to start quickly. I feel 💔 Symptoms were ignored by medics last year and someone saw a growth last June in his lung and never told us. I just hope we can get treatment quickly and there’s a positive path ahead.
Jaynelovestravel profile image
Jaynelovestravel
in The Roy Castle Lung Cancer Foundation

Biopsy results of my father. Help with suggesting what I should be looking at.

Apex : Adenocarcinoma (Gleason 6 (3+3)) Tumor length percent 50% D: Lat Base : Adenocarcinoma (Gleason 7 (3+4)) Tumor length percent 60% (May be PNI) E:Lat Mid : Adenocarcinoma (Gleason 7 (3+4)) Tumor length percent 65% F: Lat Apex: Adenocarcinoma (Gleason 6 (3+3)) Tumor length percent 50% G: Target
Apex : Adenocarcinoma (Gleason 6 (3+3)) Tumor length percent 50% D: Lat Base : Adenocarcinoma (Gleason 7 (3+4)) Tumor length percent 60% (May be PNI) E:Lat Mid : Adenocarcinoma (Gleason 7 (3+4)) Tumor length percent 65% F: Lat Apex: Adenocarcinoma (Gleason 6 (3+3)) Tumor length percent 50% G: Target
DRKC81 profile image
DRKC81
in Prostate Cancer Network

Biopsy results post MRI . Help with suggestions on read up and treatment options ( Gleason 3 + 4)

Apex : Adenocarcinoma (Gleason 6 (3+3)) Tumor length percent 50% D: Lat Base : Adenocarcinoma (Gleason 7 (3+4)) Tumor length percent 60% (May be PNI) E:Lat Mid : Adenocarcinoma (Gleason 7 (3+4)) Tumor length percent 65% F: Lat Apex: Adenocarcinoma (Gleason 6 (3+3)) Tumor length percent 50% G: Target
Apex : Adenocarcinoma (Gleason 6 (3+3)) Tumor length percent 50% D: Lat Base : Adenocarcinoma (Gleason 7 (3+4)) Tumor length percent 60% (May be PNI) E:Lat Mid : Adenocarcinoma (Gleason 7 (3+4)) Tumor length percent 65% F: Lat Apex: Adenocarcinoma (Gleason 6 (3+3)) Tumor length percent 50% G: Target
DRKC81 profile image
DRKC81
in Advanced Prostate Cancer
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Talabostat Plus Pembrolizumab shows promise for mCRPC with Adenocarcinoma

In a phase 1b/2 study (ClinicalTrials.gov Identifier: NCT03910660), BXCL701 was evaluated in combination with pembrolizumab, a PD-1 inhibitor, in mCRPC patients with adenocarcinoma phenotype as well as in small-cell neuroendocrine carcinoma (SCNC).
In a phase 1b/2 study (ClinicalTrials.gov Identifier: NCT03910660), BXCL701 was evaluated in combination with pembrolizumab, a PD-1 inhibitor, in mCRPC patients with adenocarcinoma phenotype as well as in small-cell neuroendocrine carcinoma (SCNC).
Graham49 profile image
Graham49
in Advanced Prostate Cancer

PSA monitor indicated with hx of colon cancer?

Male age 46 with recent discovery of adenocarcinoma arising in Tubulovillous adenoma, G3 differentiation, Tumor budding score (Bd2) imtermediate, tumor extension into the submucosa (SM1 level) Pathologicaal staging at this time is p T1, NX.
Male age 46 with recent discovery of adenocarcinoma arising in Tubulovillous adenoma, G3 differentiation, Tumor budding score (Bd2) imtermediate, tumor extension into the submucosa (SM1 level) Pathologicaal staging at this time is p T1, NX.
MotherK profile image
MotherK
in Colon Cancer Connected

New and scared

I’ve just been diagnosed with Metastatic adenocarcinoma of the lung and am starting palliative treatment of Carboplatin/Pemetrexed/Pembrolizumab therapy on Tuesday. This all has come completely out of the blue to me, and I understand very little of what I might expect.
I’ve just been diagnosed with Metastatic adenocarcinoma of the lung and am starting palliative treatment of Carboplatin/Pemetrexed/Pembrolizumab therapy on Tuesday. This all has come completely out of the blue to me, and I understand very little of what I might expect.
Damonaldinho profile image
Damonaldinho
in The Roy Castle Lung Cancer Foundation

Decision time. Input welcome

The median survival for patients with metastatic castration resistant prostate adenocarcinoma is approximately 2 to 3 years."
The median survival for patients with metastatic castration resistant prostate adenocarcinoma is approximately 2 to 3 years."
Miccoman profile image
Miccoman
in Advanced Prostate Cancer

New Diagnosis - feeling overwhelmed

Adenocarcinoma - Right Lat Base <5%, Left Mid 15%, Left Lat Mid 40%, Left Apex 10%, Right Apex 50% and Right Lateral Apex 15%. All with no Perineural or lymphovascular invasion. ROI - Adenocarcinoma approx 80% of tissue with perineural invasion and no lymphovascular.
Adenocarcinoma - Right Lat Base <5%, Left Mid 15%, Left Lat Mid 40%, Left Apex 10%, Right Apex 50% and Right Lateral Apex 15%. All with no Perineural or lymphovascular invasion. ROI - Adenocarcinoma approx 80% of tissue with perineural invasion and no lymphovascular.
ProgFish profile image
ProgFish
in Prostate Cancer Network

Opinions requested – biopsy pathology report

I felt my biopsy pathology report was light on details: LT Anterior Base, Biopsy: Prostatic adenocarcinoma, Gleason score 3+3=6, involving 6mm and 70% of the submitted tissue RT Anterior Base, Biopsy: Prostatic adenocarcinoma, Gleason score 3+4=7, involving 4mm, 1 mm and 60% of the submitted tissue
I felt my biopsy pathology report was light on details: LT Anterior Base, Biopsy: Prostatic adenocarcinoma, Gleason score 3+3=6, involving 6mm and 70% of the submitted tissue RT Anterior Base, Biopsy: Prostatic adenocarcinoma, Gleason score 3+4=7, involving 4mm, 1 mm and 60% of the submitted tissue
climb4blue profile image
climb4blue
in Prostate Cancer Network

Changing from Adenocarcinoma to small cells or Neuroendocrine?

Can it be Adenocarcinoma turn to small cells or Neuroendocrine? My dad’s bone metastasis when diagnostic of prostate cancer but only recently he feels hurt / uncomfortable at hip and / or leg. Thank you in advance for your sharing and comments.
Can it be Adenocarcinoma turn to small cells or Neuroendocrine? My dad’s bone metastasis when diagnostic of prostate cancer but only recently he feels hurt / uncomfortable at hip and / or leg. Thank you in advance for your sharing and comments.
Dawn80 profile image
Dawn80
in Advanced Prostate Cancer

Another 'alternative' therapy: phenothiazines (Phenergan)

2 years ago, when I was diagnosed with Stage 4 adenocarcinoma, a friend pointed me towards https://www.canceractive.com/article/using-phenergan-promethazine-to-treat-cancer which certainly looked interesting.
2 years ago, when I was diagnosed with Stage 4 adenocarcinoma, a friend pointed me towards https://www.canceractive.com/article/using-phenergan-promethazine-to-treat-cancer which certainly looked interesting.
pt45 profile image
pt45
in The Roy Castle Lung Cancer Foundation

Tylex Intro

B PROSTATE, L APEX; CORE BIOPSY: INVASIVE PROSTATIC ADENOCARCINOMA, GLEASON SCORE 3 + 4 = 7, GRADE GROUP 2, (5% CRIBRIFORM GLANDS), INVOLVING ONE OF ONE CORE; 12 MM TUMOR LENGTH (90% OF PROSTATE CORE).
B PROSTATE, L APEX; CORE BIOPSY: INVASIVE PROSTATIC ADENOCARCINOMA, GLEASON SCORE 3 + 4 = 7, GRADE GROUP 2, (5% CRIBRIFORM GLANDS), INVOLVING ONE OF ONE CORE; 12 MM TUMOR LENGTH (90% OF PROSTATE CORE).
TylexGP profile image
TylexGP
in Advanced Prostate Cancer

What does recent biopsy mean positive for NKX3.1?

Results reveal tumor cells in iliac node positive for NKX 3.1 while INSM1 & synaptophysin "show very rare positive cells." and adenocarcinoma in one lung. A chromogranin A test shows an upward trend, from 52 (9/20) to 86 (11/21). We're meeting with his oncologist tomorrow.
Results reveal tumor cells in iliac node positive for NKX 3.1 while INSM1 & synaptophysin "show very rare positive cells." and adenocarcinoma in one lung. A chromogranin A test shows an upward trend, from 52 (9/20) to 86 (11/21). We're meeting with his oncologist tomorrow.
julyturqsee profile image
julyturqsee
in Advanced Prostate Cancer

High Gleason, Low PSA

Biopsy from TURP: Prostatic adenocarcinoma, Gleason score 4+5=9 (Grade Group 5), involving approximately 90% of submitted tissue. Focal mucinous features. Perineural invasion identified in this case. Intraductal carcinoma of the prostate identified.
Biopsy from TURP: Prostatic adenocarcinoma, Gleason score 4+5=9 (Grade Group 5), involving approximately 90% of submitted tissue. Focal mucinous features. Perineural invasion identified in this case. Intraductal carcinoma of the prostate identified.
mysticmini profile image
mysticmini
in Advanced Prostate Cancer

Dad's end of journey

He had brain metastasis due to complications of his adenocarcinoma turning to a neuroendocrine diferenciation. Even we tried our best, dad broke his hip so he was not eligible for receiving docetxactel either Thanks so much for all your support and your help during this journey
He had brain metastasis due to complications of his adenocarcinoma turning to a neuroendocrine diferenciation. Even we tried our best, dad broke his hip so he was not eligible for receiving docetxactel either Thanks so much for all your support and your help during this journey
Noel91 profile image
Noel91
in Advanced Prostate Cancer

stage 4 prostate cancer metastasis bone

* Diagnosed in mid Sept 2021 * Gleason all 3-4 but one core was 4-3 with cancer on the nerve which spred to the bones T3, T4 and Iliac rib bone ridge all about 1cm or less * PSA 16 - * 7 0ut 12 cores had prostate adenocarcinoma * Started Lupron and Casodex Sept 22 * Oct 20th PSA 2.5 and Testoterone
* Diagnosed in mid Sept 2021 * Gleason all 3-4 but one core was 4-3 with cancer on the nerve which spred to the bones T3, T4 and Iliac rib bone ridge all about 1cm or less * PSA 16 - * 7 0ut 12 cores had prostate adenocarcinoma * Started Lupron and Casodex Sept 22 * Oct 20th PSA 2.5 and Testoterone
northstarlight profile image
northstarlight
in Advanced Prostate Cancer

More aggressive options for Stage 1 cancer post lobectomy.

Tumour was adenocarcinoma (80% lepedic 20% acinar) no detection of it spreading anywhere else.
Tumour was adenocarcinoma (80% lepedic 20% acinar) no detection of it spreading anywhere else.
Leonardo_C profile image
Leonardo_C
in Lung Cancer Support

Prostate Biopsy Results

Region of interest #1, A, needle biopsy: - Prostatic adenocarcinoma, Gleason Grade 3+3 = score of 6, involving 4 of 6 cores, measuring 6 mm in linear extent, 8% of tissue - See description Prostate, right lateral base, B, needle biopsy: - Prostatic adenocarcinoma, Gleason Grade 3+3 = score of 6
Region of interest #1, A, needle biopsy: - Prostatic adenocarcinoma, Gleason Grade 3+3 = score of 6, involving 4 of 6 cores, measuring 6 mm in linear extent, 8% of tissue - See description Prostate, right lateral base, B, needle biopsy: - Prostatic adenocarcinoma, Gleason Grade 3+3 = score of 6
blueseas45 profile image
blueseas45
in Prostate Cancer Network

RP 2019 now rising PSA and PSMA with most likely metastatic lymph node- any comments or advice on treatment plan?

Below is pathology from RP- Prostate (Radical Prostatectomy, TS-19-05686, 2/4/2019): HISTOLOGIC TYPE Adenocarcinoma (conventional, NOS) GLEASON SCORE, DOMINANT NODULE 3+4=7 Grade Group 2 40% Pattern 4 (tertiary pattern 5) TUMOR EXTENT Tumor dimension (max): 24.0 mm LOCATION, DOMINANT NODULE
Below is pathology from RP- Prostate (Radical Prostatectomy, TS-19-05686, 2/4/2019): HISTOLOGIC TYPE Adenocarcinoma (conventional, NOS) GLEASON SCORE, DOMINANT NODULE 3+4=7 Grade Group 2 40% Pattern 4 (tertiary pattern 5) TUMOR EXTENT Tumor dimension (max): 24.0 mm LOCATION, DOMINANT NODULE
WickedNeptune profile image
WickedNeptune
in Prostate Cancer Network

Ovarian Cancer clinical trial - ACTOv

I haven't had a diagnosis of Ovarian Cancer myself, but I am a twice diagnosed patient myself- Wilms tumour in 1991 and Cervical adenocarcinoma in 2019, so finding out about new treatments on the trials I am involved with gives me hope for future patients.
I haven't had a diagnosis of Ovarian Cancer myself, but I am a twice diagnosed patient myself- Wilms tumour in 1991 and Cervical adenocarcinoma in 2019, so finding out about new treatments on the trials I am involved with gives me hope for future patients.
Krobbo278 profile image
Krobbo278
in My Ovacome
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