Ending 2 years of Acalabrutinib & Venetoclax

[JDG45]

At the end of March I will finish taking 2 years of Acalabrutinib & Venetoclax under the Majic trail. During this time my adverse effects have been minimal and all my blood counts are reasobale and I feel great. Now I'd like to know if anyone has experienced adverse effects from stopping the medication. My wife and I have almost stopped traveling for 2 years. On April 1 we are leaving for the Azores for 10 days. Might I need any medications to bring with me?

[Zia2]

Congratulations. Very nice to read you did well. Thank you for being in the trial. Perhaps more of us will be able to have this treatment in the near future. Enjoy your trip!

[Packrat]

Hi! I finished 2 years of V&0 last May. Not a trial. I've had no problems after stopping, but I do get monthly ivig infusions since my igg has been low for quite awhile. Have a great time!

[Zigster49]

Congratulations on getting through the two years! I am on the same study and end in May. Like you, I have stuck close to home. Has your oncologist said anything about how long it will take for your lymphocytes to improve after ending treatment? Enjoy your trip!

[JDG45 in reply to Zigster49]

Zigster49:

At the start of the trial my ALC (absolute lymphs)was 171.4 on7/5/20923 it was 42. Then on 10/1/2023 it went down to 1. Now it is .53. I hope it doesn't go any lower. I will end the trial on March 25.

Needless to say I'm a happy camper.

Where are you being treated? I'm at Dana Farber.

Take care and stay well.

. On 7/11/23 it we

[Zigster49 in reply to JDG45]

I’m being treated at Fred Hutch in Seattle. My absolute lymph was .60 last week.

Enjoy your trip!