Muscle and joint pain.

[Westie11-]

A few days ago I read on here about people who are on Acalabrutinib are suffering with muscle and joint pain. My question is - did you stop taking the tablets or reduce the dose or continue to suffer with the pain? I haven't yet discussed this with Dr's so looking fir advise. Thanks.

[SLLJOHN]

Halve the dosage worked for me

[flyhigher]

Like you, I'm on acalabrutinib and generally stiff, achy and knackered to boot, with my back regularly giving me gyp.

My GP recommended I self-refer to physiotheraphy (easy to do). Had a series of monthly assessments and was given 'gentle' exercises to do at home (12 sessions a week, only of about 5 mins each). Things improved. Now currently have had 2 sessions of 6 each one hour long at the local hospital. Definite improvement. Starting to believe I can start walking again without having to prop up every other lamppost and gatepost.

Also, there was a CLL Support (UK) webinar on Thursday covering fatigue which included muscle and joint pain - wherein the experts conclude that exercise is the best medicine for said nuisances, not reducing meds. It's available online - I really would recommend having a look because I could never understand why, being on acalabrutinib which is keeping numbers at bay, I should feel so tired and achy.