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Abiraterone
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Taking Abiraterone with food
I have been taking for the last six months or so, 3
abiraterone
with my evening meal and then one at bed time. This certainly dropped my PSA initially, but now it is rising again. Has anyone any experience of taking one with each meal throughout the day?
I have been taking for the last six months or so, 3
abiraterone
with my evening meal and then one at bed time. This certainly dropped my PSA initially, but now it is rising again. Has anyone any experience of taking one with each meal throughout the day?
NiallMcC
in
Advanced Prostate Cancer
7 years ago
CRPC & Prednisolone or Dexamethasone. Neutrophil to Lymphocyte Ratio [NLR].
A 2015 paper [2] details a Phase II study "among chemotherapy naïve CRPC patients who had not received prior
abiraterone
or enzalutamide therapy."
A 2015 paper [2] details a Phase II study "among chemotherapy naïve CRPC patients who had not received prior
abiraterone
or enzalutamide therapy."
pjoshea13
in
Advanced Prostate Cancer
7 years ago
STAMPEDE - Zytiga at ADT initiation.
Abiraterone
can clearly help many more prostate cancer patients than was first thought.
Abiraterone
can clearly help many more prostate cancer patients than was first thought.
pjoshea13
in
Advanced Prostate Cancer
7 years ago
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Abiraterone - "Prostate cancer trial stuns researchers: 'It's a once in a career feeling' "
ID=60498&sortMenu=101001 https://www.theguardian.com/society/2017/jun/03/prostate-cancer-therapy-study-
abiraterone
“
Abiraterone
not only prolonged life, but also lowered the chance of relapse by 70% and reduced the chance of serious bone complications by 50%,” James said.
ID=60498&sortMenu=101001 https://www.theguardian.com/society/2017/jun/03/prostate-cancer-therapy-study-
abiraterone
“
Abiraterone
not only prolonged life, but also lowered the chance of relapse by 70% and reduced the chance of serious bone complications by 50%,” James said.
JLS1
in
Advanced Prostate Cancer
7 years ago
STAMPEDE - Zytiga at ADT initiation. NEJM Paper.
Abiraterone
(1000 mg) with prednisolone (5 mg) was given once daily.
Abiraterone
(1000 mg) with prednisolone (5 mg) was given once daily.
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Early Abiraterone plus ADT gives survival benefit, but may not be accessible to Aussie's for a while.
As you may be aware, there has been a lot on the internet recently about adding
Abiraterone
to ADT early before becoming castrate resistant and a significant survival benefit.
As you may be aware, there has been a lot on the internet recently about adding
Abiraterone
to ADT early before becoming castrate resistant and a significant survival benefit.
paulofaus
in
Advanced Prostate Cancer
7 years ago
Resveratrol & ARV7
Since it lacks the ligand binding domain but retains the intact DNA binding domain, ARV7 is constitutively active, which makes ARV7-positive prostate cancer responsive to neither
abiraterone
nor enzalutamide.
Since it lacks the ligand binding domain but retains the intact DNA binding domain, ARV7 is constitutively active, which makes ARV7-positive prostate cancer responsive to neither
abiraterone
nor enzalutamide.
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Favorable Casodex withdrawal
So it looks like I'm buying time before I have to start taking Zytiga (
abiraterone
acetate). My point is, when things start looking bleak, good things can and do happen.
So it looks like I'm buying time before I have to start taking Zytiga (
abiraterone
acetate). My point is, when things start looking bleak, good things can and do happen.
Hidden
in
Advanced Prostate Cancer
7 years ago
Melatonin & AR-V7
Given that constitutively active androgen receptor splice variants, in particular AR-V7, have been shown to confer resistance to
abiraterone
or enzalutamide, and that activation of NF-κB and reactivation of AR signaling are involved in prostate cancer progression and CRPC development, it would be of
Given that constitutively active androgen receptor splice variants, in particular AR-V7, have been shown to confer resistance to
abiraterone
or enzalutamide, and that activation of NF-κB and reactivation of AR signaling are involved in prostate cancer progression and CRPC development, it would be of
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Advanced Metastatic Prostate Cancer
I asked this question to my doctor and he is waiting for results on a study of Zytiga (
abiraterone
acetate) and that we may want to start with that before my two years are up with Lupron. Has anyone taken or are taking Zytiga? What is your experience with the drug?
I asked this question to my doctor and he is waiting for results on a study of Zytiga (
abiraterone
acetate) and that we may want to start with that before my two years are up with Lupron. Has anyone taken or are taking Zytiga? What is your experience with the drug?
grahaminator63
in
Advanced Prostate Cancer
7 years ago
Medicines to b avoided with Ibnutrib
http://www.mayoclinic.org/drugs-supplements/ibrutinib-oral-route/before-using/drg-20084873 Some other medications that shouldn’t be consumed while taking this drug are: ·
Abiraterone
· Amprenavir · Aprepitant · Carbamazepine · Ciprofloxacin · Clarithromycin
http://www.mayoclinic.org/drugs-supplements/ibrutinib-oral-route/before-using/drg-20084873 Some other medications that shouldn’t be consumed while taking this drug are: ·
Abiraterone
· Amprenavir · Aprepitant · Carbamazepine · Ciprofloxacin · Clarithromycin
Anilbhard
in
CLL Support
7 years ago
Abiraterone [Zytiga] & the Neutrophil-to-Lymphocyte Ratio [NLR]
In contrast, in patients with baseline NLR >5, NLR-change to <5 after eight weeks of
Abiraterone
was associated with worse survival and should be interpreted carefully.
In contrast, in patients with baseline NLR >5, NLR-change to <5 after eight weeks of
Abiraterone
was associated with worse survival and should be interpreted carefully.
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Advanced Prostate Cancer: Research Update
Making the Most of Hormone Therapy Some of the most exciting research focuses on how and when to best use two drugs,
abiraterone
acetate (Zytiga) and enzalutamide (Xtandi). They bring testosterone levels down to almost nothing, which starves prostate cancer cells of that hormonal fuel.
Making the Most of Hormone Therapy Some of the most exciting research focuses on how and when to best use two drugs,
abiraterone
acetate (Zytiga) and enzalutamide (Xtandi). They bring testosterone levels down to almost nothing, which starves prostate cancer cells of that hormonal fuel.
motosue
in
Advanced Prostate Cancer
7 years ago
Genetics tests: Genetics tests-what suggested for G9 mCRPC with low PSA, failed Zytiga
PSA under 1. but creeps/ 8/2016 Lupron given & will continue- 9/6/16 Tests : bone met bone scan,2 MRI, RESULTS:- Spine T6-10; L3 and pelvis,ribs 9/16start
abiraterone
4 250mg tablets and prednisone 2 5mg tablets each day 9/2016 18 spot radiation PSA: 5/15-- .01 6/15---.01 8/15---.05 10/15---.10 11
PSA under 1. but creeps/ 8/2016 Lupron given & will continue- 9/6/16 Tests : bone met bone scan,2 MRI, RESULTS:- Spine T6-10; L3 and pelvis,ribs 9/16start
abiraterone
4 250mg tablets and prednisone 2 5mg tablets each day 9/2016 18 spot radiation PSA: 5/15-- .01 6/15---.01 8/15---.05 10/15---.10 11
anniesea
in
Advanced Prostate Cancer
7 years ago
Common Treatments for Advanced Prostate Cancer
Newer types of hormone therapy include:
Abiraterone
acetate (Zytiga). This pill stops prostate cancer cells (and other cells) from making androgens. It's approved for men with advanced prostate cancer who have tried other hormone therapies. Enzalutamide (Xtandi).
Newer types of hormone therapy include:
Abiraterone
acetate (Zytiga). This pill stops prostate cancer cells (and other cells) from making androgens. It's approved for men with advanced prostate cancer who have tried other hormone therapies. Enzalutamide (Xtandi).
motosue
in
Advanced Prostate Cancer
7 years ago
Duration of Treatment ... with Abiraterone Acetate or Enzalutamide.
Duration of Treatment in Prostate Cancer Patients Treated with
Abiraterone
Acetate or Enzalutamide. Pilon D1, Behl AS2, Ellis LA2, Emond B1, Lefebvre P1, Dawson NA3.
Duration of Treatment in Prostate Cancer Patients Treated with
Abiraterone
Acetate or Enzalutamide. Pilon D1, Behl AS2, Ellis LA2, Emond B1, Lefebvre P1, Dawson NA3.
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Abiraterone or Enzalutamide in Advanced CRPC.
KEYWORDS:
abiraterone
; advanced prostate cancer; castrate-resistant; enzalutamide PMID: 28101887 DOI: 10.1002/pros.23309 [PubMed - as supplied by publisher]
KEYWORDS:
abiraterone
; advanced prostate cancer; castrate-resistant; enzalutamide PMID: 28101887 DOI: 10.1002/pros.23309 [PubMed - as supplied by publisher]
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Role of free testosterone levels in mCRPC.
A total of 34 patients with continuous measurements of FT levels and mCRPC status underwent therapy with docetaxel,
abiraterone
acetate, enzalutamide, cabozantinib, carboplatin or cabazitaxel.
A total of 34 patients with continuous measurements of FT levels and mCRPC status underwent therapy with docetaxel,
abiraterone
acetate, enzalutamide, cabozantinib, carboplatin or cabazitaxel.
pjoshea13
in
Advanced Prostate Cancer
7 years ago
ADT + Chemo vs ADT followed by Chemo
This was true in spite of the fact that most of the ADT only men were later treated with chemo once they became castration resistant, and many had
abiraterone
or enzalutamide. In other words, early chemo combined with ADT worked better than late chemo after ADT had stopped working.
This was true in spite of the fact that most of the ADT only men were later treated with chemo once they became castration resistant, and many had
abiraterone
or enzalutamide. In other words, early chemo combined with ADT worked better than late chemo after ADT had stopped working.
AlanMeyer
in
Advanced Prostate Cancer
7 years ago
Blacks Respond Better Than Whites...When Treated For mCRPC with Zytiga
https://www.urotoday.com/recent-abstracts/urologic-oncology/mcrpc-treatment/93775-prostate-specific-antigen-response-in-black-and-white-patients-treated-with-
abiraterone
-acetate-for-metastatic-castrate-resistant-prostate-cancer.html
https://www.urotoday.com/recent-abstracts/urologic-oncology/mcrpc-treatment/93775-prostate-specific-antigen-response-in-black-and-white-patients-treated-with-
abiraterone
-acetate-for-metastatic-castrate-resistant-prostate-cancer.html
gusgold
in
Advanced Prostate Cancer
7 years ago
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