Methotrexate

[Nikki246]

I'm starting on 10mg on Sunday night (as I have a dressage competition on Sunday afternoon I'm worried about side effects.) Just wondering how others have got on with it. Nurse has warned me about sickness etc and I have Folic Acid to take Monday night.

[Joan59]

You should leave a few days between taking your methotrexate and folic acid. I've been taking them for years and they say not to take them so close together. If in doubt ask your pharmacist. Hope this helps.

[Nikki246 in reply to Joan59]

Thanks the lupus nurse at Guy's hospital has told me to take the folic acid 24 hrs after taking the Methotrexate. She said I may need to take the folic acid more than once a week depending on how sick I feel.

[rosella24 in reply to Joan59]

I have been injecting Methotrexate once a week for a few years now. I take Folic acid every day except for the day I inject the Methotrexate. I have never experienced any side effects!

[tall-tim]

Hello Nikki,

I have never experienced problems with it, apart from a bit of sweating - I am on 15 mg weekly. My advice is to proceed as normal. If something bad happens - well, I'd put it down to experience. Scleroderma is a rolling circus.

Best wishes,

Tim

[clementlu]

Hello, i started metho 3 weeks ago with 15mg for 2 weeks and i took one 20 mg which will be my weekly dose from now..i didnt have any side effects at all..it a good idea to take them at night and for the acid folic(i guess 5mg) it s 24 hrs after metho..some people take 1mg every day...good luck and let us know .....

Lucie

[Joanmbb]

Is there a chance you could take Methotrexate on Saturday morning instead of Sunday? I always was really tired when I took mine for maybe about 8 hours after.

[Jensue]

I take 17.5 mg every week & built up gradually to that dose, I was told it should be taken the same day each week and on the other 6 days I take folic acid. At first I used to feel quite sick but doc suggested coke a cola and I found it worked for me just kept sipping it over a few hours after the MTX but now it doesn't bother me.

[scotgirl]

I've been taking methotrexate for about 3 years and I've had no side effects at all, i take 15mg every Friday and am absolutely fine on it. I was warned about the potential side effects and was a little wary of taking it but I've not had any problems. I hope you tolerate it well!

[Nikki246]

Thanks everyone, I'm glad that some people get on with it as was starting to worry that I'd only heard negative things! Will let you know on Tuesday how I feel!

[MilkMaid]

I was diagnosed a month ago and started on 10mg once a week with folic acid on the other six days, I take mine at night and haven't had any worrying side effects.

[MilkMaid in reply to MilkMaid]

Hi Nikki, just wondered how you got on with the Methotrexate, my dose increased to 15mg per week a month ago & still have no side effects - no better either!

[Nikki246 in reply to MilkMaid]

Hi sorry to hear you haven't yet benefited from the Methotrexate. I'm still on 10mg. I think it has helped, I'm getting less joint pain but my hands still swell (but have no idea if the Methotrexate is meant to help the swelling or not). The Only side effects I get are tiredness the day after taking it and mouth ulcers. I have increased the folic acid to 6 days a week, so hoping this will help.

I hope you get it sorted soon. Are you on other medication as well?

[MilkMaid in reply to Nikki246]

No, just the methotroxate and folic acid. They did say it could be 3-6 months before I noticed any benefit so fingers crossed!

[Nikki246 in reply to MilkMaid]

I'm surprised you're not on hydroxychloroquine as well. I take that and amitriptyline for nerve pain as well. Might be worth asking.

[clementlu]

Goodmorning Nikki,

how are you doing ? hope all ok

Lucie

[Nikki246 in reply to clementlu]

Hi I'm not too bad thanks. I took the methotrexate on Sunday and it knocked for 6. I ended up sleeping a fair bit on Monday and had a sore throat. Tuesday I felt ok energy wise but throat felt dreadful so went to the Dr, who frightened the life out of me telling me if my white blood cells are up I'd have to go into hospital. Anyway had test on Wednesday and everything is ok, but not allowed to take Methotrexate until I've spoke to Guy's hospital. They were meant to have phoned me 25 mins ago. ☹️ Not happy as waited to speech them but need to do the school run and my phone won't pick up. Now don't know what to do!

[clementlu in reply to Nikki246]

I do understand your concerne ...please let me know how it will go....

[MilkMaid in reply to Nikki246]

Hi Nikki, I hope the meds have settled down a bit for you now.