Methatrexate/hydroxychloroquine

[Den73]

Hi,looking for advice please.Two weeks ago I was put on 20mg Methatrexate for Sjorgens syndrome but really had a bad reaction. Spoke to the pharmacist and she sent me iff to the GP as she said I was suffering Methatrexate toxicity, so i did not take the next weekly dose, got an appointnent to see rheumatologist in April.

I have been told about another drug hydroxychloroquine, would this one be better according to anyones experience? Or any other advice....I am new to this all ...since July 2023.

I have only been taking prednesolone and busy decreasing dosage, was on 60mg because of GCA, I am down to 30mg

Thank you in advance of the experience of this group.

[Oscaromega]

Hi. I have been taking hydroxychloroquine for several years for my Sjorgrens Syndrome with no ill effects so far. Eyes have to be regularly checked because of potential damage which the drug may cause. Recently prescribed Azathioprine instead of Methotrexate for newly diagnosed Rheumatoid Arthritis. That drug chosen because Methotrexate can affect lungs.

I had a very bad reaction to Azathioprine (similar to your experience with. methotrexate) so another drug has been prescribed, with success.

I continue to take Hydroxychloroquine and all is well.

Wishing you all the best with this.

[Den73 in reply to Oscaromega]

Thank you Oscaromega ...yes I read the possible sude effects on the eyes I already have very sore eyes and having a problem getting an appointment with the opthomologist nearest appointment booked for August! When I asked the rheumatologist if he cannot bring it forward, his words were its what it is😔 not the answer I expected.

[Oscaromega in reply to Den73]

I'm sorry to hear of the rheumatologist's response.I cannot remember how I was prescribed eye drops however the NHS ones weren't great. My ophthalmologist (for routine eye tests) recommended Hycosan Extra which I purchase over the counter. I find these worth the expense . They last 6 months.I believe I received NHS eye screening after about one year of taking hydroxychloroquine and receive these annually.

I wish you all the best Den73

[Den73 in reply to Oscaromega]

Thank you Oscaromega I appreciate your comments. I am going to have a serious discussion with my rheumatologist.

Thank you for your good wishes.