CA125 ftom 532 to 425 after one chemo!

[sara_mamani96]

Hello everyone,

Can I know if this little decrease after one chemo is normal ? I know people respond differently to chemo but what is your max decrease?

Thanks for sharing

[Jules_PPC]

I know that they didn’t test mine until after the second treatment, and my drop was dramatic, 5800 down to 81 after two treatments.

But my doctor had also removed most of my omentum during my exploratory surgery. Which was where he physically saw most of the cancer.

I was also taking supplements to combat the cancer. If you’d like to know about them you can Private Message me, I’m not sure I’m supposed to write things like that here.

It’s still early days for your Mom, hang in there.

JTD

[GwenHP]

One of the things to keep in mind is that most of us that are long term survivors didn’t start out with chemo. Most of us had surgery first. My CA125 just prior to surgery was over 6500. With the surgery alone it dropped to ~600. Once I got into chemo they really weren’t focused on my CA125 until after the 3rd cycle and the hope was that it would be in the “normal” range with the lower the better. But then again that point in my treatment would be more comparable to Mom’s situation sometime after your mom has her surgery.

To me that seems pretty impress for your mom’s ca125 to drop 20% in one cycle.

[sara_mamani96 in reply to GwenHP]

Thanks for you response again. Talking to you gives me lots of hope.

[journal]

Sara

What subtype is mom? Response is often based on this.

Also wondering why they didn't drain ascites before op and chemo...this is done to relieve pressure and determine subtype.etc.

I'm wondering if a better response occurs with op then chemo? I had adjuvant chemo...4rounds of carbo paclitaxol..the op..then only 2 more chemo. I recurred in 7 mo. The literature says they are comparable....but you wonder. My ca125 was 4200 and dropped to 12. Probably still some microscopic disease present. It's all so very distressing at times.

[sara_mamani96 in reply to journal]

Hi Journal,

I just came through my previous message from last year as my mom apparently recurred after 6 month frontline treatment. I am very terrified and hopeless now even more than last year. Can you please share what was your 2nd line treatment and how long have you been in remission if you are.

Thanks