Brave Bold Cancer Thrivers, I am ER+, HER2 negative and I, finally after four months, have an oncologist I just love (she's so thorough with everything and very kind and caring), and my treatment is working! I am on Ibrance and letrozole and in only 2 months majority of the tumors have shrunk in half. The lesions on my liver disappeared completely. The only thing is one tumor, in the right lung, hasn't changed yet hasn't grown. but it's so early on this drug combo that the oncologist is doing a wait and see. The other small tumors in the lungs are diminishing. No bone mets. The other sites like near my left ovary and my right adrenal gland also shrunk in half. I am amazed that the tumors shrunk so quickly even had lesions disappear completely. My cancer is a fast growing where within a month and a half my tumors grew up to over 6 cm like under my armpit and 5 cm in my collar bone and over 4 cm in my right lung. I mean between a PET scan in September and CT scan in November I had progression. I didn't start letrozole until November 16th and Ibrance on December 13th. So just two cycles of Ibrance. I had genetic testing and have no mutations at all. I want this combo to work for a long time. And I am on full dose of the Ibrance. I am so happy 😊. I just wanted to say my news. Thank you for reading!!
Tumors Shrinking! : Brave Bold Cancer... - SHARE Metastatic ...
Tumors Shrinking!
So happy to read your good news 😁 long may it continue to work for you. I know for some on here have got to NED on this combo.Best of luck with your treatment and enjoy your weekend celebrate 🥳 xxx 🤗
Thank you!! 😊 I would love to get to NED too, hopefully someday!! I am enjoying the news despite the fact I have a sinus infection from a cold, my whole family caught a cold. My neutrophils are low like 1.7 so not surprised at the sinus infection. But since it's shrinking the tumors, I am so not worried about my nose 🐽. Lol 🤣
That is wonderful news. I love this chat room .. there is HOPE . All of you give me hope ….. I am on Ibrance and Exemestane since Feb 2022… n have been stable. No metastasizing . I hope I can stay on this … n i wish n pray for you as well.
Dancing, I love this chat room too. Everyone is so supportive and not only that sharing our stories and things that go bump in the night -smh and now what kinds of things we deal with nearly daily. I pray too that you can stay on your drug combo for many many years.
Wonderful news! Hoping it works for many years to come!
So happy for you! I’m on Ibrance and Letrozole too. Been working for 3 1/2 years so far and hopefully for many more years. And remember, even stable is good!
Thank you for your reply! 😊 I hope to have a long time on them. Yes stable is good, I will take it ☺️!
Brilliant news & long may it continue. My neutrophils come in around 1 on Ibrance & Fulvestrant, so 1.7 sounds good to me. That's near the bottom end of the normal range. Speedy recovery from your cold.
Do you feel like tiredness from the low neutrophils? I been feeling tiredness, as long as I keep moving I'm ok but sitting down I find myself falling asleep, nodding off.
I'm not overly tired. I'm retired so luckily don't have to push myself too hard. Most mbc meds seem to have fatigue as a side effects. I couldn't tolerate Ribociclib or Abermiclib at all... I felt so unwell, like I was wearing a lead overcoat, couldn't eat. Palbociclib no problem, but only on 75 mg because of the neutrophils effect. Risk of infection is my main concern. Hopefully we may hear of some magic remedy to boost the neutrophils. Long may you respond well to your meds.
I am also tired and when I sit and after eating I fall asleep. This is everyday. Breakfast sit n I wake up an hour later dinner is the same . I feel like I am always apologizing to my husband who constantly checks on my m he tells me after 40 years of working you are allowed cat naps he calls them.
Happy for you! I had 5 years progression free on that comb - l expect you to that and more.
Oh thank you! Five years that's awesome 😎!!
So happy for you!!! That’s wonderful news!
Thank you HelenWi🤗!
Love a good news story! Congratulations.
Thank you so much!!
Great news!!
Congratulations! Hope you get over your sinusitis quickly.
Wishing you all the best with your ongoing treatment!
Discocat, thank you for the well wishes!! I am to pick up the antibiotics for my nose 🐽 today..
amazing news! I love hearing it as I worked for pfizer oncology! I long may it continue!
Bettybuckets, the oncologist I had before said that she doesn't see the drug working for not even a year. My son heard her say this to a new nurse she was training. My son came to me upset and said he didn't like my oncologist and I certainly agreed with him. I knew from the lovely thrivers here that many of you have had awesome results with this drug. I certainly don't need or want such a Debbie downer as my oncologist. So I got a new oncologist one that is kind, caring and upbeat and positive about my cancer treatment. It makes a difference who's in your life including your medical care team when you are dealing with life and death issues.
That is such great news! Hope you continue to have good results with this protocol. I have been on it since November of 2020 and so far, so good. Sending hugs and prayers.
Thank you for the hugs and prayers 🤗!
You are welcome!
so happy for you! I’ve been on Ibrance & Arimidex for 2 and a half year now. It took a year before my tests were clear of any cancer, but it did happen. I still get tested every 3 months with a blood test and a CT scan every 6 months. I’m so glad you have a great oncologist: it’s half the battle. I’m sending you lots of good vibes for your healing.
You're so right having a great oncologist is so important! Thank you for the well wishes.
Huge news. I'm so happy for you.be patient I have such a good feeling. They always just want us to be stable but to have that much shrinkage is SOO HUGE!!YOU found the right combo. So exciting. Be patient with the other. To have that much shrinkage in amsuch a short amount of time is really profound . Blessings friend
Colacancer, thank you for your blessings, I know that much shrinkage in a very short amount of time blew me away! I was a little stunned. I was not expecting that and I expected it just enough to be stable. After it was just two months! I know God is looking out for all of us, he works through miracles as well as doctors and modern medicine. God bless you.
GOD IS ALWAYS GOOD MY FRIEND.. BLESS YOU TOO.
Great news! May it continue!!!
Nicollo, thank you for your reply!
That is awesome news. Any it continue 💕. I have been on those meds for 41/2 years . Always stable but no shrinkage. A bit of progression in my spine now. Had 5 rounds of radiation and now waiting to have scans on the 19th.
Totheriver, I hope your scans show good results. Please let us know. Hugs and prayers 🤗 for you!!
Thank-you so much💕
whoo hoo!!! Congratulations 🎈 I’m on this combo too, 3 years and counting on many more ❤️
Thank you!! I feel so supported and blessed 💗 by you and everyone here🤗💗.
That is so awesome! God is always good! Im glad that you also found a great oncologist.
I’m also on that combo for 15 months now and scans are good, no evidence of disease!
God bless us all!🙏❤️
Taurus28, Oh wow no evidence of disease that is so wonderful!! Yes God does bless us in many ways.
such awesome news. This makes us hopeful and mentally stronger . And this site saves my sanity, love it and everyone on here so much! Take care and enjoy this moment- hugs, Elizabeth
Thank you Elizabeth for the virtual hugs 🤗. I agree this site helps tremendously.
Have been on these for 18 months now. All stable, but no shrikage (except for the first 2 months - but I think that is the Xgeva effect). A lot of fiddling with dosage due to low Neturofils, but feel Ok now. Still worried before each 3-monthly scan (next on the 20th), but physically they got it right in the end. Also have high hopes to stay on this for a bit longer.
Good luck!
Oh wow shrinkage in the first two months that's good. I hope you have a good long run on your drug combo too!! Prayers that your next scan has good results!!
So glad to hear you are doing good I started Letrozole before sugery in 2022 and started Zometa infusion after sugery. Didn't know i was to get the infusion every 6months I'm to start back on the infusion in April. May God bless us all on this Cancer journey. Stay positive. Love you lots 💗
Are you on Ibrance also? It's such a rollercoaster ride that's for sure. I will stay positive and love you lots too 💗!!
This is great news! So glad the Ibrance is working so well for you, monkeygirl62!! Keep on keepin’ on!
Thank you, Aquamoron!! I really appreciate it 😊.
I just love hearing all the great news about Ibrance … I had the 2 Pet scans n on 2nd one they could not see my tumors in breast or lungs. But they lowered my Ibrance to 75mg which is the lowest cause of my anemia …low neutrophils . I have blood work every month n they say yes start your next cycle or no I am immune compromised n have to wait a week go back have blood work n start my cycle. My diarrhea has stopped but I have been on the Ibrance n Exemestane for 2 years n a 5 months n after 75 mg stop working I am getting anxious about starting another medication.
Dancing. I now have my Ibrance reduced to 100mg and feel so much better not like the unwell feeling I had on the 125 mg. I am so sorry to hear that you are having to change your treatment drugs. Ugh. It's anxiety provoking for sure because we don't know if the new drug regime will work as well or work at all. But remember, sweetie you have lots of options now unlike when I had breast cancer 27 years ago that offered tamoxifin or traditional chemo (which was never offered to me as I was very early stage). I have to now go temporarily off Ibrance, I will be starting chemo and radiation for a tumor that wasn't shrinking (it wasn't growing either) and it turns out to be small cell lung cancer. I now have another primary cancer at the same time as my MBC. After I finish with that treatment for small cell lung cancer I will go back on Ibrance at the 100 mg dose. Life sure throws us curve balls that's for sure.
My onc reduced my Ibrance to 75 mg … n I hope it keeps my cancer dormant … cause 75 mg is the lowest for Ibrance . I have tolerated the 100 mg well other than some intestinal issues n anemia n low neutrophil counts. I am on Imodium n still afraid to go out to dinner … my husband n I use to do breakfast n dinner out a few times a week. I sleep after eating cat naps n it is 430 am n I cant shut down my brain. My tv does put me to sleep. N i should put it on a timer n tell my husband to just leave me where i am on couch. I will continue to pray for you all on this site.
I am so happy you have found the onc for you!! It has made all the difference for me. Best wishes to all as we journey onward! ♥️♥️♥️
Thank you and she's been a godsend because now I have another primary cancer small cell lung cancer. Just one tumor and it's not growing but wasn't shrinking so she wanted another biopsy on it. Now I am temporarily off Ibrance when I start chemo and radiation. I am staying on letrozole though and when I am through the chemo radiation I will go back on Ibrance.
I wish you all the best.
I feel blessed I have found all of you wonderful warriors. When I try to explain to a family member how I am feeling they just don’t get it. However, if I seem like I am complaining or I should say venting … you all get me . These are real issues. I find myself not telling my family member. I don’t complain to friends … I try to stay positive n if I tell someone I haven’t seen that I have MBC they are amazed how positive I am. N as always I am still dancing.
Dancing, same with my family, they just think I am complaining they just don't get it at all. I too don't feel like telling family or friends because they are clueless. Personally, I can't really blame the clueless and really, I hope none of them ever have to go through what I am going through. I prefer my family remain clueless. I wish to save them this heartache. Hugs 🤗 Alicia
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