xeloda/Capecitabine question

[caw517]

I’ve been on xeloda for almost 5 mo now.

3x 500mg twice a day . One week on.. one week off. Wondered what schedules others are on. Also how often do you see onc and how often do you do bloodwork? So far xeloda seems to be working… which is great!! Just wondered about the timing etc! Thanks.

[Silver126]

I was on Xeloda 1500 mg in the morning and 1000 mg at night, two weeks on and one off. I saw my oncologist at the beginning of a new cycle every 21 days and on that occasion I had bloodwork too. Unfortunately it worked only seven months… It was a good treatment which gave me no side effects

[caw517 in reply to Silver126]

Thanks! I hope you have found a new treatment that works!

[Silver126 in reply to caw517]

I was on Afinitor + Exemestane for two months but it didn’t work. Now on IV chemo Caelyx with great improvement on liver. It’s tolerable and most of all, at least for me, it doesn’t cause hair loss. I hope Xeloda works for a long time for you.

[caw517 in reply to Silver126]

Thanks! Hope your treatment continues to go well.

[Chamisa]

I just finished my first two weeks of capecitabine. Now I have one week off before I see the oncologist for blood work, then repeat the cycle. 1500 mg in the morning and 2000 mg at night. Red, sore hands and feet by the end of two weeks, but I keep them moisturized. Otherwise, easier on me than Ibrance. No nausea — Ibrance caused a constant, low-level of background nausea.

[Chamisa in reply to Chamisa]

My onc changed my schedule (same dosage) to week on/week off to stave off worsening hand-foot syndrome (feet were red and had been hurting but no cracks, peeling, blisters etc.). This is MD Anderson doc. She says the Xeloda is still effective with this schedule. 🤞

[LDR1]

I recently started Xeloda at 3000mg/day (1500mg each in morning and eve), 14 days on and 7 days off, followed by an oncologist checkup & bloodwork before starting the next round. After 2 cycles the foot pain became an issue so the dose was reduced slightly to 2500mg/day (3 pills in AM, 2 in PM) so we’ll see how that goes.

Besides some occasional foot pain & constipation I feel good, and actually more energetic and optimistic than when I was on Ibrance.

[Fiercefighter13]

I just started Xeloda almost two weeks ago after progression on Ibrance/Letrozole, then more progression on Verzenio/Faslodex, then more progression on Faslodex/Anastrozole, and finally a severe allergic reaction to Piqray. I started Xeloda with 3x500 twice a day, 7 days on then 7 days off (I’m on my 7 days off until this Friday). I got super nauseated so my doctor lowered the dose to 2x500 7 days on and 7 days off. Hopefully I adjust to it and can increase the meds back up. I see my doctor every 28 days and get blood work every 28 days as well. Hoping the best for you, for all of us, it’s good to be alive…even when the road gets tough!! Take care!

[Bettybuckets in reply to Fiercefighter13]

I’m 2 weeks ahead of you in starting xeloda. Had bad HFS to start so lowered the dose to 2000/ day but will build back up to 2500/ day with 7 days off every other week. I’m bouncing back and no blisters. Started walking a bit and swimming most days while I am on vacation in nz. Happy to be out in cape so I could still travel. I am seeing my oncologist here in nz in a week just to catch up.

[Photo-Bug]

I started Xeloda at 1000mg twice a day, one week on and one week off. About 6 weeks out, the hand and foot syndrome started so my dosage was reduced to 500mg in the AM and 1000mg in the PM. I can't remember how long I was on that dosage, maybe about 9 months, but I had to stop because of sore feet. I think I did labs monthly with good results. Except for my letrozole, I liked Xeloda the best.Good luck on your journey with it.

Sharon

[Hotlantaphatz]

Hi! Same here one on one off capecitabine. Onc changed from 3 on and one off due to HFS and skin rash. No other side effects. Next Ct scan in two weeks after @2 months in the treatment. Hand in there! Best X

[Hotlantaphatz]

Hi! I am on the same 1 week on 1 week off. I am doing well. Minimal side effects. New found energy. No tumor progression.