Medication working

Hi, my mom has been taking ibrance and letrozole for almost 3 years for her metatisized bone cancer. The last few weeks her pain is back and she is very weak. Does this mean her cancer has got worse or does it mean her medication may not working. She is having her scan next week. I am praying there is alternatives.

[M43bcmgreenblue]

Hi Puffy123

I hope there are more alternatives for your mom, gook luck to her and she will be in my prayers take care.

[Oltu]

I hope her cancer not got worse , good Luck to your Mom, she will be in my prayers!

[Red71]

It could be either one. Your body does get acclimated to the medication and you need more, on the other hand, she has been on her medication for a fairly long time, so her cancer could have gotten worse. You will have to have patience to see what the scans say, I know that is hard to do!

[Hidden]

Thanks guys for the comments, she is having her scan tomorrow so I guess we will know more soon.

[sancarlos]

Hi, My journey on cancer started 35 years ago. I’m 3 years on Ibrance and Letrozole. Previously, I was on only Letrozole for 20 year before I had new bone lesions. My last scans remain stable but the level of fatigue on the last week of the cycle can be overwhelming. My doctor agreed to having a 2 week break in between. Definitely helps my white count. I’m able to get some energy to start the next cycle.Hang in there!

[Hidden in reply to sancarlos]

Yes they are giving my mom a break too. The last few days she seems to regaining back her energy. She has her scan tomorrow, so I am hoping everything has stayed the same.

[viennagirl in reply to sancarlos]

Wow, 35 years with cancer and still here with us. It is wonderful and gives us all hope. You are obviously quite strong and a real fighter. I was told that Ibrance and Letrozole are new drugs. At least that is what the BC cancer agency told me two years ago. So I suspect you were on other drugs before you were put on Ibrance (Palbociclib and Letrozole). I have been on that combination for two years and have recently had scans that showed NED. I am happy but still scared because I don't want the cancer to come back. There is some hope coming in some new evidence that might indicate a cure is in our future. I sure hope so. It is difficult to live under this scary cloud of worries.

Yes,I hope you continue to get help so that you are not so tired.

All I can say is hang in there and take good care of yourself. Hugs Viennagirl

[Dragonfly2 in reply to sancarlos]

That third week can be a kicker…I agree…and my ONC has occasionally given me a second week off. Her thoughts are that the medication will continue to work if the body remains strong. Blood counts matter. It’s the quality of life that matters also!