I have to say that I am beside myself. My first scans on Xeloda show increase size and number in Liver Tumors.
This is the 3rd drug that has failed for me in the past 6 months. Ibrance, then Piqray now Xeloda.
I am really worried. I spoke with my oncologist yesterday and there are 3 classes of IV Chemos. Xeloda, Taxols and Doxils. It looks like I'm on to Doxil after a liver biopsy. But I am only 52, with 4 kids from 12 to 22. I am not ready to go, but I have started planning.
I asked the doctor to give me a prognosis at this point. He said 2 years if Doxil doesn't work. If it does work, many more years but I am a bit melancholy today.
Has anyone had progression on Xeloday, stayed on it then later scans show stable or reduction in the tumors?
Karina
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klhowe
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I am so sorry to hear this, my heart goes out to you.
Have you had genomic testing(Guardant 360) or considered a clinical trial as Sandra has suggested? My oncologist did some research for me but I did the bulk of it and conferred with her regarding which trial would work best for me. I am currently participating in the following trial: clinicaltrials.gov/ct2/show...
I'm happy to report after two months my tumor markers have trended down, the lesions on my liver are smaller and my bone mets are stable.
August 5th it was 1600, September 4th 800, October 4th 400, I have not received results for this month due to a cyber attack at our hospital. I feel great, so I suspect it has gone down.
I was freaked out when my number was 672. Now I feel that I can deal with my doc tomorrow. This roller coaster is so difficult when we are at the bottom of the rails. Thanks so much. This site is a blessing.
Oh, dear Karina, I'm so, so sorry! I can only imagine how incredibly stressful this must be...
I'll note that, from what I've seen on the board, it seems that sometimes it takes the power of the IV chemos to really make a difference. These are truly the "big guns" in our arsenal...I hope they work well, push things back, and give you many good years...
It is scary when things don’t work but lots of ladies here are doing really well on other chemos- it is often a case of finding the right one. Wishing you luck and sending love.
I'm sorry you are going through the disappointment of medication results. I too have experienced a short span on all the medications they have tried me on . I started back on IV chemo Vineorelbine. Still a short response time. My oncologist suggested to start a clinical trial. It is a small one. There will be around 12 people. I live in Canada . 3 from back east (Montreal) 6 from Vancouver and 3 from Edmonton .It will be opening in 1 week for applications
My understanding is you must have advanced breast cancer along with short result spans . The name of the drug is Tomivosertib and it is taken with Paclitaxel. I hope this information helps. Take care be safe
You are so kind to share your knowledge when you’re facing your own medication challenges. I sincerely appreciate this. It’s another reason I’m grateful I found this board.
I found this board three years ago when, after 20 years in remission of stage 3, I advanced to stage 4 in the lining of my left lung. My pleural fluid stayed really small and lining decreased just on letrozole until now. Now liver and some bone as well with decreased pleural fluid. I guess I had assumed, although I do understand the lymphatic system, that my progression would be to the lung and this caught me by surprise. I am awaiting med decision now, probably tomorrow. The important thing I want to say here today is that this site and communicating with you ladies meant the world to me three years ago and once again now. I am nervous about the next steps.
I’d be nervous too. It’s very natural given what we face. Please know we will be here for you whenever you need us.
Hi Karina
Sorry I have no experience of any chemo drugs, but I wanted to let you know that you are in my thoughts. You fight for those kids, that Mum strength is very powerful. Hoping your next treatment is the one suited to you.
I haven't got anything useful to advise, but I want to send you love and hugs. Hang in there - I have learned from this forum that there are many treatments and options. I am gutted for you. This is so horrible but the next treatment may change everything. Hugs to you and your children xx
I’m just starting Xeloda too, and hoping (but not sure) that it’s working, but at my last appointment my doctor said, “It’s a good drug, but there are lots of good drugs out there!” ...so I hope we can all take some comfort from that. Good luck! My thoughts and prayers are with you! Please let us know what next step you and your doctor decide to take.
Phew, this is tough for you. It’s a story none of us want to share. I’m sorry you are facing these challenges. I expect other posters can offer specific insights. I am sending long distance love.
Karina-- First, I'm so sorry for the latest news. Keep your head up. I was told 2 years ago I had 6 months and I got on an immunotherapy and taxol that have shrank my tumors (so far). Nothing's ever guaranteed, but there are so many new lines of treatment available out there. After your good cry, start looking/asking/investigating other options with your doctors. And, yes, clinical trials are an option as well. Stick with it. Sounds like you have a great family support and you have a cadre of support on here as well! <3
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Did anyone go back on target and hormonal treatment after Xeloda?
Moving on from Xeloda to Doxil
Capecitabine (Xeloda)
Joining the Xeloda team next week
