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Nausea and appetite loss on ibrance

MegandOllie profile image
12 Replies

Did anyone experience loss of appetite and nausea on ibrance? I just started my second round and just thinking about food makes me queasy. But I know I need to eat! What’s did you do?

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MegandOllie profile image
MegandOllie
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12 Replies

Hi and welcome. It’s understandable you have loss of appetite. When we are first diagnosed it hits us hard and there is so much to take in. It puts us into shock for a while. Once you settle with your medication you hopefully will gain your appetite back.

I’m on Ibrance and Letrozole. I do feel queasy in the mornings and some days. I drink plenty of water and that helps. My appetite has returned. I have been on these meds since March last year. I also take ginger to settle my stomach but you will find ladies on here find other things to take beneficial.

When I have my week off from Ibrance I feel fine but the first few days back on it I feel shattered. I think it’s a case of go with what your body is telling you. I personally wouldn’t take any supplements without consulting your Oncolgist first. That’s just me though. Hope your tummy settles. Keep up that intake of water (I hate it but needs must).

Take care and keep posting

Best wishes

Cheryl

Red71 profile image
Red71

Between meds and radiation I had no appetite for the first two months. People were so worried that they let me eat anything that I thought tasted good! Toast and cheese and fruit appealed the most, as well as yogurt. I ate full fat Greek plain yogurt with fruit and granola a lot! It gave me protein since nothing else gave me much. After a couple of months it got better and now I eat everything although meat is not as appealing as it used to be. Give yourself some time and eat whatever tastes good, even if it is ice cream!

Hugs to you and Ollie,

Elaine

MyMiracle13 profile image
MyMiracle13

I agree with Cheryl that the impact of the diagnosis can cause loss of appetite. That happened to me and what I did was to drink Prosure to offset any weight loss. That being said, I didn’t experience any nausea though so what you are experiencing may be related to Ibrance. There’s a package insert that comes with Ibrance or you can google to check if nausea and loss of appetite are side effects of Ibrance. Wishing you well.

My wife is on Ibrance. Her appetite is quite good, all things considered, but to keep any nausea at bay her oncologist prescribed 4mg Ondansetron, which seems to do the trick if taken an hour before food once or twice a day.

Shelly1009 profile image
Shelly1009

I've been on Ibrance about 6 months. the first few months I had mild nausea and some decreased appetite but it's seemed to settle down. Are you taking the capsules or the tablets? If it's the capsules make sure you're not taking them on an empty stomach. I take mine about an hour after dinner. And if you're taking the capsules maybe ask your onco for the new tablet form. I understand they're easier on the stomach and don't have to be taken with a meal. Good luck!!

mariootsi profile image
mariootsi

I have found this improves with time and my primary care doc perscribed mirtazapine to help me have an appetite. It is also for anxiety which helps with the shock of all this nonsense. I also drink alot of water.

hanus profile image
hanus in reply tomariootsi

I love you calling this "all this nonsense". Made me laugh!!!

mariootsi profile image
mariootsi in reply tohanus

Oh good! It is nonsense isn't it?

Iwasborntodothis profile image
Iwasborntodothis

I have had both and it varies from cycle to cycle. Some times just looking at food makes me feel sick. I nibble little bits of crackers and nuts throughout the day and when I don't feel sick I try to eat a little more. I used to try to track my side effects by day but they have not been that predictable.

Hang in there is all I can say and stick with this group of wonderful ladies for advice.

SMPG profile image
SMPG

I suppose you take Ibrance 125 mg. Doctors usually like to start patients aggressively at the highest strength. I took the opposite approach, starting on the lowest, 75 mg and with first one week on one off, then the next cycle was 2 weeks on and one off and then finally, the third the subsequent cycles of 3 weeks on and one off. I was then prepared to escalate to 100 mg and see what happens. I had zero side effects on this protocol. I mean from Ibrance. I have some joint point (occasionally) from Letrozole but luckily nothing from Ibrance. And when I talked with my provider about starting the 100 mg, she said that since I am doing so well on the 75 mg, I should continue that. From what I heard others saying, as long as you take it, it does not make much difference if it 75 or more. So, maybe you should start switching to a lower strength and see if your side effects will not disappear. Good luck

pinkrv profile image
pinkrv

I have just restarted on Ibrance 100 mg tablets and taken 6 doses. I started with the 125mg and felt so sick after 8 doses. My ANC was too low and I had to stop. I do have nausea but it is occasional. In my case I have determined that I need to be sure to keep my bowels moving. Also, I will change part of the day to liquids, soups, broth, and crackers which helps. Heavier foods makes it worse. If I can stay hydrated it seems to help. You may want to check with your oncology team if you are not drinking enough to make sure you are not dehydrated. When I get that way regardless of treatment they will give me IV fluids. In addition, I was instructed to try to eat smaller meals throughout the day to help the nausea.

hanus profile image
hanus

No loss of appetite, but some foods taste so different (not good different). especially eggs which I love and still try to gag down! I drink a lot of protein shakes which I like and are pretty good for you. Atkins and Premier Protein. Might give it a try. God bless.

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