Ibrance Side effect question.

[Phillipians4and6]

Hi ladies. Hope all is well and everyone is staying sane and safe. Does anyone have back discomfort on ibrance and or ibrance and Faslodex? It’s not like a pain but a pressure, gassy type thing. Seems to happen toward the end of the cycle. I do have lung and pleura Mets of the left side. This happens on the right mostly.

[Hidden]

Hi Phillipians4and6-

I do somewhat regularly get a very mild "sensation", not really an ache, but just enough to make me aware, and it feels like I would imagine a slightly swollen organ in that area would feel. A couple of times I've looked up a map of the human body to see if it might be a kidney? liver? stomach? one of those other things (like, what is a gall bladder, really?)...? Whatever it is, it goes away...I have looked at my labs to make sure whatever organ-related measures (liver, etc.) are normal, and they always are... I also haven't pegged this to a place in my Ibrance cycle, i.e. I haven't thought about it...

...Sorry, I wish I could be less vague! Between my memory, lack of attentiveness, and very rudimentary knowledge of human anatomy (!), I'm not much help! Hopefully someone more knowledgeable will respond soon... Lynn

[Phillipians4and6 in reply to Hidden]

Thank you Lynn. That actually was very helpful. And yes. Like a swollen organ back there is a good way to describe it.

[PJBinMI]

Do let your onc know about this. Ibrance damaged my right lung permanently. I noticed that I was getting short of breath and saw a pulmonologist who diagnosed something called Interstitial Lung Disease, that he explained as being like gunk between the air sacs. I now have two inhalers to use every day and still cannot walk very far til I Have to stop and get my breath. It's been over 3 years since I stopped Ibrance and the symptoms remain. So I tend to be biased about Ibrance!

[Kiera49]

I get back pain right at the bottom sometimes when walking although as I haven't had pain in my back as I haven't had denusumab since March I'm guessing that drug is the culprit, due to have it again next month