Xeloda side effects?

[Duffles]

Has anyone had stomach muscle spasms and/or back and rib pain with Xeloda? Only been on it 11 days and feeling ok til this.

[MacroMom]

I was on Xeloda for 7 months and never had that, but "abdominal or stomach pain" is listed as one of the common side effects. I suggest letting your oncologist know right away. Perhaps they can lower your dosage or give you a week off. I was at 1300mg twice a day, 7 days on, 7 days off. The only side effect was the hot burning feet, and that only started after several months and a trip to a warm climate. Hope you get relief soon! Patty

[Duffles in reply to MacroMom]

Thanks for the info. My muscle spasms aren’t really painful...more like irritating when trying to go to sleep. So far (well second week of 1000mg twice a day) no big side effects. My onc said starting low dose to slow the foot effect. Take my first Denusomab shot tomorrow. (Lots of bone Mets. Had huge tumor on spine removed and spinal fusion in November!) Only tried Ibrance 2 week before having to stop,

So glad to try SOMETHING that I hope will stop progression! Why did you stop Xeloda? What has your experience been in this ongoing story?

[MacroMom in reply to Duffles]

Glad to hear you are starting on a lower dosage, that seems wise to me too. I've had Denosumab since November 2017, first every other month and more recently about every 3 months.

I was diagnosed Oct 2017 with "innumerable" bone mets (all over ribs, pelvis, spine but not on extremities) and a few liver mets. I have been incredibly fortunate with the bone mets not to be in pain. My first treatment was just daily Letrozole which worked amazingly well for a year, then gradually stopped working. I tried Faslodex and Ibrance for a few months but my neutrophils tanked and the cancer marker and liver mets increased a lot. The liver mets concern my oncologist a lot more than the bone mets because I need that organ to live! I switched to Xeloda last June and was happy with it; it's been around a long time and has a good track record. I had minimal foot pain or peeling, in fact it only got worse in November when we were in Hawaii for 2 weeks instead of chilly Oregon! But the Xeloda stopped working too so I recently started on Abraxane, an IV chemo similar to Taxol but easier for me to take. So far so good....I did lose my hair and of course feel more fatigue the first few days, but not debilitating fatigue, no nausea or digestive issues. It also tanks blood counts and with Covid-19 circulating I may be on it every other week just to keep my counts high enough in case I'm exposed.

I hope the surgery you had in November helped a lot with the pain, and may you have a long easy ride with Xeloda. Some other women on this site were on it much longer than I was. Take care!

[Olliecardew]

Me my ribs are killing so worried it’s Mets belly got better within 48 hours now it’s ribs and chest