Ibrance not working any longer.

[dasypien]

I took Ibrance with flosedex (sp?) stopped working mine is met to my liver. Now they want to give me xeloda which is chemo I dont want chemo I thought there were more medicines available than chemo I guess not and the radiologist says i am a candidate for radioembolizm but doc says not worth it cause I most likely have somewhere else...

[MacroMom]

Ibrance didn’t work for my liver mets either; after 3 weeks of Xeloda my cancer marker dropped 200 points. Don’t let the “chemo” label scare you off; Xeloda has been around since 1998 and seems to work especially well on liver mets, perhaps because it is metabolized in the liver. I used the search feature here for “Xeloda” before starting it and found lots of success stories and good advice.

Ibrance is often called “targeted therapy” but my pharmacist said it is a type of chemo too. I certainly am having far fewer side effects with Xeloda than I did with Ibrance.

Changing treatments is always difficult - wishing you peace, wisdom and healing with this next step!

[Barbteeth]

Hi

I’m on Ibrance letrazole combo and had a liver met increase in size...had a pet scan to see if there were any more mets...there weren’t so I’ve had radiotherapy for it and staying on same drugs for now

Nightmare isn’t it

Have you had a pet scan?

Barb XX

[BangorBelle in reply to Barbteeth]

Sorry Barb, there are so many people and symptoms I think I sent you a message about radiotherapy being difficult to deal with on spine, when I now see it was for your liver. Which hospital do you go to? We are so behind the curve over herein N Ireland. I was put straight on to Taxol when my liver mets got larger. I am changing to private care. Just getting loose ends tied up. Unfortunately my oncologist is away for two weeks. Hope you are doing better. My oncologist has suggested a newer version of Taxol (nab Taxol also with Avastin).I get depressed having to have the Picc line and weekly chemo as I feel I can't live whatever time I have left to the full. I feel so tied and envy everyone on tablets who can go on holiday, swim etc. Really glad for you all. Just wish I had been given some more options before IV chemo. I hope you are feeling a lot better, I think you were temp stopping COC temporarily. Hope it all works well

X

[Barbteeth in reply to BangorBelle]

Thank you for your good wishes

Although I’m able to go on holiday it’s no fun being tired and in pain...I feel as if I spoil things for everyone else and almost feel they’d be better off if I wasn’t there

Barb xx

[Hidden in reply to Barbteeth]

Barb,

As a daughter of a mom with MBC I can tell you that living life with you-tired or not is just the way it is and we choose to take it. If you feel well enough to go on holiday-go for it! If you need to rest then rest but your family and friends (and you) will be glad for the experience and celebration! Sending you love and strength!

[Kimr2081]

I was on Xeloda for 9 months. I didn't want chemo again either but honestly for the most part physically I felt fine. The one side effect that it has that doesn't seem to escape people is what it does to your hands and feet. They say its kind of like hand, foot and mouth disease but my kids never got that so wasn't sure what to expect. It started slowly and up until about the last 6-8 weeks I was on it did it become a problem. Having said, that I could still function but it is a really annoying feeling. I felt it mostly on my feet. They got really peely and sometimes i felt like i was walking on gravel. When it really bothered me was when I went to work and had to put on pumps. They always felt better with open shoes or with socks and tennis shoes. Honestly, I could have dealt with it longer but it quit working. Good luck - oh and keep your feet and hands really moisturized.

Kim