More info on Ibrance than I have ever seen!

[Godbeforme]

I know I posted this earlier, however, when I went back to read it again, not there. Maybe I messed up but at any rate, I am posting again because this has the most exhaustive info I have seen on ibrance. I wanted to know specifically about the shelf life, etc. and that's how I came upon this. You can read about the shelf life and special handling towards the tail-end of the article. God bless and heal us all in Jesus name, amen! Knowledge IS power and the bible says "my people perish for lack of knowledge". medicines.org.uk/emc/produc...

[Barbteeth]

Hi there

I’ve just read this interesting information..some of which I was aware of

One thing that jumped out at me was a drug interaction between Ibrance and Metformin...the latter is one of the drugs that Jane Mclelland recommends in her book and the Care oncology clinics prescribe...I’m seriously intending to go to the COC clinic in London but this has shaken me up a bit...do these clinics actually keep up to date?

I want to help myself with off label drugs but not at the expense of messing up my cancer meds from my oncologist

What do you ladies think?

Barb xx

[Godbeforme in reply to Barbteeth]

Thank you! I'm glad you mentioned that because I take metformin and missed seeing that part ... there is so much there! What about them saying no special storage needs for the medicine when I've heard some say it has to be shipped in a cool container? God bless you and heal us all in Jesus name, amen! <3

[Barbteeth in reply to Godbeforme]

There’s no special way to store them...sometimes these rumours spread just from hearsay...I just keep mine with my other stuff

Barb xx

[Red71 in reply to Godbeforme]

In the winter mine is shipped to me in a normal package. In the summer it comes with a cold pack but also says not to worry if the cold pack is melted. I think they just don’t want it to get too unbearably hot during summer shipping. I think it comes from somewhere in the southern states of the US. I store it in my cupboard.

[Godbeforme in reply to Red71]

yep, it gets very hot here on the Texas coast as well ....

[Godbeforme in reply to Barbteeth]

I read and read but could not find anything about metformin and ibrance, can you be so kind as to tell me exactly where that is? Thank you! <3

[Barbteeth in reply to Godbeforme]

Section 4.5

Heading ..in vitro with transporters and metformin is mentioned

I don’t totally understand as I’m not a laboratory scientist..just concerned me

Barb xx

[Godbeforme in reply to Barbteeth]

thank you dearheart!

[Godbeforme in reply to Barbteeth]

i found it but did not understand what I read ... it is way over my head; maybe someone can put it in layman's terms.

[Hidden in reply to Barbteeth]

It mentions in vitro study so that would be pregnant women. Metformin is a diabetic drug so they may be checking how the two interact. Best to ask a doctor.

[Godbeforme in reply to Hidden]

yeppers!

[Barbteeth in reply to Hidden]

In vitro means in a test tube not in a living person..that’s in vivo

Barb xx

[Red71]

Thanks for posting this. Even though it is difficult to read, this is the kind of information that all drugs should have. Beware of drugs that say they can help but only post glowing reports but not the down to earth nitty gritty of how it was studied and what interacts with it and who was studied.

[Godbeforme in reply to Red71]

Right! I have the right to know what I'm swallowing! You're welcome, I learned some things. One thing I found a bit unsettling was where it says 'no dose adjustment necessary if over 65', but I'm sure i misunderstood, one would hope so anyway. I'm over 65 and if it makes me ill you had better adjust my dose. I don't like what my onc already said, and I haven't even started taking ibrance yet. He said he doesn't do the 75 mg dose, well this is where I would get an attitude if I needed that because it should be the patient's choice I feel, it's our lives on the line. peace and God bless you and heal us all in Jesus name, amen!

[Red71 in reply to Godbeforme]

I think it means that being over 65 doesn’t mean that you should automatically start at a lower or higher dose or some other adjustment for age. I had to smile at that because it called those patients elderly. No way am I elderly! I just happen to be 71, but elderly I’m not!

As far as your oncologist not using 75 mg., that’s a shame. I started at 125 but dropped twice to 75 because of low neutrophils. Despite that, my numerous bone mets as well as two spots under my arm totally disappeared. It works even at the lower dosage.

[Godbeforme in reply to Red71]

yay! good to hear! soldier on warrior! <3

[Tam-56 in reply to Red71]

Amen! ❤️❤️❤️

[Barbteeth in reply to Godbeforme]

Ha I love you...you’re feisty like me!!

Barb XX

[Barbteeth]

Thanks Sandra

You’re cleverer than me!

That’s reassured me

Barb xx

[Barbteeth]

Yes I am...get my scan results Wednesday..eek!.. then will decide...I’ve already had copies of my records and send them to COC so just need to let them have a look at the latest ones...tricky decision...however if this stuff works and doesn’t interfere with what I’m taking then I’ll probably do it

There are studies being done on metformin now and I haven’t time for years of trials to be done...feel like time is running out for me...

Barb xx

[mariootsi in reply to Barbteeth]

Best of luck on Wednesday! Will be thinking about you and seding positive results your way!

[Godbeforme]

ty!

[Barbteeth]

Hi Sandra

Thanks for that...my last 2 scans have been at two month intervals due to my tumour markers going up so she’s being extra cautious but it just means I have more anxiety..at least I’m getting monitored

Yes I do remember we were diagnosed around the same time with similar diagnosis

I’ll keep you informed if I go to that centre in London

All the best

Barb xx