I've Been on ibrance and letrozole for 10 rounds. I would like to know if anyone has bee on it for more than two years, after having stage 4 BC. I find it very scary to think about how much these drugs may end up costing me financially. Too many things to worry about, side effects, cancer recurring, and now the cost. Sometimes I just want to bury my head and scream. But I have to be thankful for each day.