Have been a sufferer of rls for almost 30 years. Been sleeping for 2 moinths without ANY rls now. What I use is 2x 500mg L-argenine at breakfast and 5mg (½ a 10mg tablet) Pax directly before bedtime. It takes a week or two for the meds to work fully, but I immediately felt the difference. L-Argenine is freely available over the counter and not to expensive. It helps the body produce nitric oxide which relaxes blood vessels. Pax is a generic and very cheap prescription med used to relax patients at pre-operation stage. You could start of with higher dosages of both meds (discuss with your dr. please!) like 4x500mg l-argenine and 10mg PAX, but please try to find your minimum levels once you get your legs relaxed. GOOD LUCK AND SLEEP TIGHT.