Two new research studies on RLS from Turkey. One showing a link to Overactive Bladder, the other showing electrophysiological changes after administration of pramipexole in NEWLY diagnosed RLS patients.
Depressingly, another generation condemned to permanent damage/augmentation/ICD.
just terrifying and tragic and criminal…..
The first reference in the article actually mentioned a study that said α2δ-ligands should be 1st line treatment and mentioned ICDs but of source was ignored.
Yes. Sadly, Istanbul hospital tends to follow Germany where dopamine agonists are still first line treatment.Same here in the UK. DAs are still first line treatment.
We still have such a long way to go....
my bladder became even more over active, the same time as augmentation happened
Oh Joolsg, I don’t know how you stay sane with reports like that from countries that have access to all the up to date data on DAs and the results of prescribing to RLS sufferers, I realised that not everyone suffers the side effects but the majority will in time and then they will be truly stuffed
Kind regards HipHop1972
oh no … if it is permanent damage am I ever going to get rid of RLS?
I have severe RLS. I have tried everything there is. At one time I was taking 8 .088 Pramipexole which took me six months to come off. I also have an overactive bladder. Do I understand from your comment that Pramipexole and an overactive bladder are linked?
RLS and Overactive Bladder are linked.So whatever treats the RLS will treat the OAB.
However- there may be other causes.
many thanks for your reply. I’m on long acting OxyContin for RLS which unfortunately does not help my OAB. Nothing I take helps it.
It might not be linked to RLS. Lots of reasons for OAB. Usually spinal cord damage.
Oh how interesting! I had failed back surgery 25 years ago and my sciatic nerve was damaged.
very interesting. I’m not newly diagnosed. But as I think about it around the time I switched to pramipexole I started having stress incontinence. I had a bulking procedure. Lasted a year had a second procedure after a year. Still an issue. I was thinking of surgery. But you never know I’ll wait until I’m off pramipexole see if it stops. Just fascinating and frightening what these drugs can do , yet for me it was a miracle in the beginning. Reminds me so much of thalidomide. .
The article actually is about RLS and OAB being linked and that Pramipexole treats both conditions.So if you took Pramipexole - it should help Overactive Bladder. But not stress incontinence which can be helped by pelvic floor exercises.
And don't let them use plastic mesh/slings to help stress incontinence. My friend ran the UK campaign to get it banned after it severed bladders/internal organs.
Find a good pelvic floor physio or buy a machine that helps weak pelvic floors.
thanks. I’ve been on the fence about the mesh. My gyno really advises against it. Oh I see it was prescribed for OAB. Still interesting. Thank you for sharing them. You never know when something may shake loose.
Before you go on a dopamine agonists
For us midnight munchers
