buprenorphine with nalaxone

[kirks2092]

hello

is anyone on bupre with nalaxone please?

i was wondering is the bupre dose the same with just the nalaxone added?

many thanks

kirsty

[Joolsg]

bnf.nice.org.uk/drugs/bupre...

The doses of Buprenorphine are set out on the medication pack.

The BNF lists all the available pills with naloxone.

Which pill are you taking?

Buprenorphine without naloxone starts at 0.2mg. The average UK dose is between 0.4 and 0.8mg.

However, the lowest dose buprenorphine pill with naloxone is 1.4mg of Buprenorphine.

That's over 3 times the dose I take.

The naloxone might help reduce constipation or nausea.

[kirks2092 in reply to Joolsg]

hi jools

she’s currently prescribed 0.4 i believe

currently at the moment we are cutting individual pills in quarters so she’s taking roughly equivalent to 1 pill of 0.2 in quarters at various times. patches have made nausea worse unfortunately

as she’s prescribed 0.4 i was trying to find the equivalent dose in the bupre with naloxone

and then we continue cutting

she’s experiencing terrible nausea and the gastric issues they now believe are down to bupre unfortunately , so we think adding naloxene may be a idea but just didn’t want a different dose which may affect rls

many thanks

[Joolsg in reply to kirks2092]

The pill strengths are different. So getting 0.4mg will be difficult as the lowest dose of Buprenorphine with naloxone is 1.4mg. Cutting the pill to achieve 0.2mg will be VERY difficult.And unfortunately- naloxone isn't available as pills separately.

I am so sorry that she is still struggling with nausea.

The only alternative might be to switch to Targinact and ask for 6 x 5mg pills and take every 4 hours. Targinact is usually prescribed twice a day. But thst causes interdose rebound for many people. And so taking it more regularly through the day seems to avoid this.

This disease is horribly cruel. You find a med that stops the RLS symptoms but the side effects can be intolerable.

[kirks2092 in reply to Joolsg]

thank you, will look into this

is methadone something else she could try?