I have been on Mirapex/Pramipexole for decades. I have reduced my dosage to .5mg for a couple of years and have been able to ignore the temporary (two or three days) augmentations that arise and then subside. Lately, I have been experiencing a really rough augmentation that has lasted for a couple of weeks. It is starting earlier (6 or 7). I usually take the Mirapex with dinner at 6:30, the Mirapex finally kicks in around 9:30pm but RLS will rise it's ugly head in the morning again, Usually it it has only occurred on one side of my body's arm and/or leg per day and by using a hand held massager, I have been able to calm it. Now it is affecting all limbs. I feel like a spastic. Massage isn't working. I cannot stand clothing touching my skin.
So when desperate, I google RLS and see if anyone has come up with a magical solution yet. This time, I ran into an article on Seratame which I include because some of it seems to make sense. I have ordered a bottle and will let you know in a couple of months if it helps.
seratame.com/rls-protocol/?...
Meanwhile, I would love to hear if anyone else has used it successfully and/or what you think of the premise of the article.