Candasarten and rls

[0rangetulip]

for the past three nights my rls has been quite well behaved until tonight. I take candasarten morning and evening (with evening dinner) but left off the evening one three nights ago and had a vast reduction in my rls. Tonight I thought I’d better take my evening dose and low and behold the rls is back with a vengeance. Does anyone know if there is a worsening of rls symptoms when taking candasarten?

[SueJohnson]

Yes - it is known to make RLS worse for many people and you have just discovered you are one of them. For high blood pressure propranolol (Inderal, Hemangeol,InnoPran) seems safe and there is Isosorbide Mononitrate (Monoket, Imdur) which is not a beta blocker nor calcium channel blocker. And then there are the ace inhibitors such as Zestril (Lisinopril, Qbrelis, Prinivil) and Perindopril (Coversyl). Other possibilities are: Clonidine (Catapres) an Alpha-2-Agonist used to treat high blood pressure which may help RLS, which also treats insomnia and ADHD (not a stimulant) and may help RLS, tenex (Guanfacine, Intuniv) treats ADHD and high blood pressure, prazosin (Minipress) - alpha-adrenergic blocker that treats high blood pressure so there are a number of safe substitutes.

[0rangetulip in reply to SueJohnson]

can’t make out why my iPhone doesn’t seem to be replying to posts this morning. I’ve replied to both Sue and Chris but they’re not showing up on my phone. Did they actually come through as my reply posts please?

[ChrisColumbus in reply to 0rangetulip]

This query to Sue is visible but I can't see any other Replies from you at present

[ChrisColumbus]

Candesartan is usually a second choice BP medication in the UK, generally used because an ace inhibitor such as lisinopril or perindopril has caused a dry, tickly cough that does not get better.

This happened to me on perindopril, but my GP then put me on losartan rather than candesartan.

Your (and other people's) problem with candesartan could be that you're taking it morning and evening. NHS guidance is "You'll usually take candesartan tablets once a day. You can take your candesartan tablet at any time of day, but try to take it at the same time every day." If your GP insists on twice a day, could you take with breakfast and lunch?

But if you really can't tolerate it, while I believe that Sue has seen reports that losartan can exacerbate RLS I have had no problems with it and am now RLS symptom free.

25mg a day brought my BP down but it was still a bit erratic; 50mg totally controls it. I take just one pill in the morning.

But of course we're all different!

[ChrisColumbus in reply to ChrisColumbus]

I believe a problem with some reports is that it is often difficult to tell *which* drug or food is causing the RLS symptoms, and/or whether timing & dosage makes a difference.

It wasn't until I got taken off statins; reduced sugar, artificial sweeteners and caffeine (reduced, not renounced); and continued taking magnesium citrate, that I got rid of RLS symptoms entirely (except when I lapse and binge!)

[Madlegs1]

healthunlocked.com/rlsuk/po...