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Restless Legs Syndrome

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RLS Relief

LSGW profile image
LSGW
6 Replies

RLS-at the outset I take 75mg of Pramipexole (Mirapex) which is used for Parkinson's. Within an hour, it works.

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LSGW
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6 Replies
SueJohnson profile image
SueJohnson

I assume you meant .75 mg. That is 1 and a half times the maximum amount for RLS. Did you start with that amount or work up to that dose when lower doses didn't work?

Madlegs1 profile image
Madlegs1

Absolutely crazy amount dose. I presume you mean .75. -- which is still far too high . Unless you have Parkinson?

Agree with Sue( just seen her reply)

DicCarlson profile image
DicCarlson

I assume this is a new development for you. There is still time to turn around your treatment - DAs (Pramipexole and ropinirole) - sure they COULD work great - 'till they turn into the Devil and make your RLS Soooo much worse with a condition called augmentation! First line treatment is NOT a Dopamine Agonist like Pramipexole. Read about augmentation and iron on the pinned posts (top right). Here is the Mayo Clinic information perhaps to show your doctor...

mayoclinicproceedings.org/a...

Fingerandus profile image
Fingerandus in reply toDicCarlson

hi i like your reply you just cannot withdraw from pramipexole once you are on it so dont take it. its easier with pregabalin and its easier to reduce your doses i have been on lyrica for 11 yrs prescribed them for periphial nueropathy and i might add i didnt have restless legs then i didnt get restless legs or treatment until i had my thyroid removed..

my restless legs syndrome started in 1957. suffered in silence until 2007 , then went to see a consultant neurologist who prescribed 88mgs tablet of pramipexole. once per day. immediate effect. went to see a consultant neurologist in 2020 as i was now taking three 0.18 mg with six co-codamol pain killers i felt that i needed a change. it was recommended that i try a number of different medication, all of which created bad side effects. i am now taking four pramipexole and six co-codamol . this just keeps the restless legs under control. i am now 82 years of age. regards pete.

SueJohnson profile image
SueJohnson in reply to

That's an increase in pramipexole from what you were taking not too long ago and that's a sign of augmentation. You can certainly stay on that but if you feel you need to increase it again, that's definitely a sign of augmentation. The amount you are taking is the maximum amount.

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