I switched from Sertraline to Wellbutrin. I didn't think it was affecting me negatively but didn't want to take any chance in my search to lessen my RLS symptoms. But I think Sertraline helped depression but also OCD tendencies.
What is the best OCD med for a person with RLS too ?
It took me years to discover my SSRI (citalopram) aggravated my RLS. For a while I used Wellbutrin (bupropion) but it has a strong stimulant effect on me (agitation). According to several postings in this forum the following are possible meds to look into for yourself - I do not have any personal experience with any of these drugs. Moclobemide (MAO inhibitor); reboxetine (not available in the US), tianeptine (not available in the US); agomelatine; Trazodone; Norpramin (desipramine).
Ah I am in the US. Thank you 
Same experience with Wellbutrin. Agitation. Frustrating as so called safe meds for mental health are very limited with RLS.
Sertraline
Sertraline
Sertraline and RLS
Anxiety 
Advice needed on taking Tramadol with Sertraline
