I've had rls for 30 years. I take Requip 2mg. During day and 8mg. ER at night. Different things can worsen severity, if not now later. Some drugs (benzodiazepines like xanax, muscle relaxers, etc.). Reglan (I received during surgery - the doctor had to strap my legs down while unconscious during surgery ). Caffeine (colas, coffee, tea, chocolate, sugar free candy, alcohol, and MSG ( like in Chinese food) when we switched to Chinese restaurant that doesn't use MSG it stopped when eating Chinese food. Also stress and sometimes doing too much worsens it. Hope this helps someone.
I do know this can be a debilitating disease. I can't do anything in the early to late evening because the side effects of the medication I take knocks me out. Can't sit still in movies, church, a car, etc. Without taking medicine before and then I get extremely sleepy. My sister and 2 of her kids have it. And it is genetic in a lot of instances.