Always do your own research. Trust no one, especially me.

Magnesium may actually INHIBIT dopamine release. Very bad for RLS. I have to do much much more research. Years ago I did a lot of research on magnesium and the heart and felt confident that it was a miracle drug (given intravenously) for anyone in atrial fib. But RLS???

researchgate.net/publicatio...

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This is the sixth and most recent article that indicates that magnesium inhibits the release of dopamine. That's bad, very bad. It's a good mineral, but I would take it in the morning and iron bi-glysinate at night

omicsonline.org/2155-6105/2...

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And yes Erona and Nightdancer, cream of tartar (aka potassium bitartrate) seems to facilitate the release of dopamine. So I for one have no doubt that the forum member who claimed complete relief of RLS symptoms (where every medicine failed her) from one teaspoon of cream of tartar in a glass of water before bed is on to something. But that's about double (if not more) than the RDA. And I would be afraid to take it on an empty stomach. I would have no problem taking half a teaspoon one time to see if it worked and will buy some and try next time RLS kicks in. I tried tyrosine several times based on a recommendation here but found it did not help RLS and energized me. Not something I want at midnight. It might be one of those substances you have to take for a long time (not before bed) to see benefit. I'm just in the market for a quick fix so the tyrosine is relegated to the hall closet for now.

sciencedirect.com/science/a...

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I'll just keep replying to my own post. I saw on another site that one man swears by a little mustard in water. Yuck. But of course I completely believe him. The active ingredient in mustard is curcumin also called turmeric. It's supposed to be yet another substance good for mood and elevating dopamine. And I think someone else on here mentioned turmeric and India has a low incidence of RLS. The list is probably endless of relatively harmless substances that are cheap and worth a one time shot.

huffingtonpost.ca/natasha-t...

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Thank you. I'm learning with you.

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Well I'm going one step further than reading...at least tonight. We're going by my brother's house for Thanksgiving and they have a dog and I have no choice but to take two Benedryl and an inhaler all of which give me RLS. Not to mention over-eating at night. My husband bought some cream of tartar for me this morning. I'll try it tonight - somewhere between one quarter and one half teaspoon. It scares me a little because I have a condition called interstitial cystitis and I am supposed to avoid potassium which irritates the bladder. Anyways, I'll give the tartar 60 minutes. If the RLS isn't gone I'm heading for the mustard/curcurmin. Then iron. First time in my life I'm looking forward to having RLS.

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We do have to remember that there probably are several reasons behind our RLS and Magnesium can be the reason and the cure for them who suffer from low Magnesium. And for other dopamine may not be the issue at all, the latest scientic artcles describes lack of oxygen as a major problem.

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So true. I'll look up symptoms of lack of oxygen. But dopamine agonists seem to work for a lot of people, and they are regularly prescribed by Dr. B. I am simply looking at how other substances affect our dopamine receptors and hence the release of dopamine.

[beady3]

Who ever it was wanted to know where you can buy Magnesium tabs from they sell them at H & B

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Re: magnesium- as Swedish said, those people with RLS AND a mag deficiency will no doubt be helped by supplementing the mineral. I have had an ongoing struggle with mineral balance, having overdone the calcium for years, and didn't figure it out until recently. I dutifully took extra calcium for years, originally to control muscle cramps and because it is the thing to do. But after years of this, it took the other minerals out of whack and I was dealing with the muscle cramps and twitches again, AND an irregular heartbeat which gets your attention! Several months ago I dumped the calcium and have been taking mag citrate and have noticed that RLS is under better control for it. RLS is such a booger- so very many things that can bring it on. So with dopamine in mind, perhaps a morning dose would be the best. And a side note- my joints, neck in particular, are much better now. Excess calcium apparently gets deposited in joints.

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Alright, so you are drug free, pretty pain free and RLS is intermittent. You have found your way out of the darkness and now must help others find their way out.

I take/took Taurine for irregular heartbeat during peri-menopause/menopause. Magnesium did not help as I thought for sure it would. Huge difference with the Taurine. One 500mg pill wasn't enough had to take 1000mg. I don't even care what type or brand. Taurine is essentially an amino acid which by it's very nature is readily absorbed. All the amino acids are readily absorbed, unlike the minerals and metals which have to be in a bio-available form which it seems you know about because I think you said you were taking magnesium glycinate which is a good form.

Yes, calcium does get deposited. Believe it or not I'm not big on supplements, I consider them almost like drugs. I really wanted the RLS to stop so that's why I tried iron and still take it as needed. And I really wanted the heart palpitations to stop so I took the taurine and still do on occasion. And right now I'm taking zinc carnosine for IBS which I really want to stop.

Mother Nature in her infinite wisdom knows the right proportion of nutrients that we need so living plants and animals are all we should consume (not twinkies, soda, or supplements), then we don't have to worry about imbalances. So I think on days when I over do the zinc carnosine my RLS will kick in because zinc in large quantities will compete with iron. In the right amount it helps iron to be absorbed and utilized and to make and distribute dopamine. So I assume the same is probably true for magnesium. In the right amount it is good for the production of dopamine but too much and it inhibits it's release.

All so darn complicated.