Hi everyone, I have just discovered this forum - it's a godsend.
I have had RLS for about ten years now but recently discovered after a serious ankle fracture that Tramadol completely eases my restless legs. Last week I went to the doctors for an unrelated issue, and have been prescribed the anti-depressant Sertraline (Zoloft, or Lustral, depending on where you're from). According to the leaflet you cannot mix Tramadol and Sertraline together or you risk Serotonin poisoning, so the doc prescribed me some Diazepam for the RLS in the mean time.
Long story short, the Diazepam doesn't work and I'm ITCHING for Tramadol to ease my legs, but I'm worried about the drug interaction. Has anyone come across this before? If so,is it safe...ish?
Well, another problem you might be having is anti-depressants (except maybe Wellbutrin) usually make RLS worse.
I take an ssri and it really has made my rls worse. I take co codamol to get me through. My doc did give me tramadol.at one point as I was getting too used to the the co codamol . I think it is allowed as long as you are not taking loads of it. Although it did nothing for me! Wellbutrin is really hard to get in the UK. See my other blogs and questions. It can only be prescribed off label by a willing doc. Mine isnt!!
Switch your antidepressant to the SNRI Venlafaxine it is one of the few that does not cause or exacerbate RLS