Research shows neuroinflammation and tau c... - PSP Association

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Research shows neuroinflammation and tau co-localise in PSP

HelenPSPA profile image
HelenPSPAAdministratorPSPA
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New research at the University of Cambridge with PSPA funding has shown inflammation in the brain occurs in PSP. It is found in the same part of the brain as the junk protein Tau, and is related to the severity of symptoms.

The researchers mapped both the inflammation and Tau in people living with PSP, using a brain scanning technique called tomography (PET scanning). Understanding the interaction between the inflammation and the build up of harmful Tau may provide a new way in to treat and prevent PSP in the long term.

It follows the recent discovery in PSPA’s national PROSPECT study that variations in a gene controlling the inflammation affect life expectancy with PSP. This new PET study is a key piece in the jigsaw puzzle to understand the causes of PSP, and the eventual development of a cure.

Read the research paper here: onlinelibrary.wiley.com/doi...

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HelenPSPA
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3 Replies
raincitygirl profile image
raincitygirl

I am always grateful to read any new findings offering insight into PSP and CBD. It gives me hope for the future.... 😊

Anne G

Bhakthan profile image
Bhakthan

In Ayurvedic stream of medicine, inflammation of the brain can best be tackled by the use of turmeric and pepper powder mix of 4:1 ratio and mixed with coconut oil and taken thrice daily 1 tbsp each, two hours after meals. It is well known that coconut oil is the medium of transportation of medicine to break the blood brain barrier. This could be tried by the Cambridge team before implementation.

Drjazz profile image
Drjazz

The question is whether the inflammation causes tau buildup, or whether tau buildup results in inflammation. Unlikely to be a meaningless coincidence.

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