My husband was diagnosed with Parkinson's disease in 2016 at age 68. Subsequently, he was started on therapy with Sinemet and developed episodic periods of shortness of breath that were distressing to both him and me. Cardiac and pulmonary workups did not reveal an etiology for the shortness of breath, but the neurologist did not want to blame the Sinemet as the cause. Several months later, he saw a another neurologist (a movement disorder specialist) for a second opinion on his condition. The second neurologist feels he has PSP and said the shortness of breath could be either "wearing off" between doses or a respiratory dyskinesia resulting from the Sinemet.
We opted to stop the Sinemet and the shortness of breath resolved, so my husband is reluctant to restart it. However, his condition seems to be progressing at a faster rate.
I know that PSP progresses faster than Parkinson's, but has anyone found Sinemet to provide much help and for how long?