I've been told by 3 different neurologists that no one knows the cause of PSP -- so I am putting this out there:
My husband was on prednisone on and off for 20 years for severe inflammatory small bowel disease(Crohns) - 6 small bowel resections and with that a Dilaudid addiction that took him to a detox and rehab center where he was given Suboxene. In addition he's been on all the biologic meds they use for crohns; humira, metrotexate, remicade, you name it!
My feeling is that all these toxins have affected his brain. Hoping for some feedback.