I mentioned sometime ago I would let you all know after my husband was tried on Sinemet. Well it made no difference to his symptoms and hence it has now been discontinued. However, the next medication trial, was for him to have hyoscine patches to reduce his drooling. He has had the patches now for two weeks and they have helped. More dramatically has been the changes in the last couple of days. My husband's speech has become stronger and clearer and yesterday he spontaneously started a conversation, something he hasn't done for over a year. Another improvement has been his walking, he is taking more positive steps rather than shuffling. His balance unfortunately has not improved and he now fidgets much of the time. Has anyone else experienced this type of change?