Pirads 5

[pd63]

Cousin just had MRI with some pirads 5, having tp biopsy soon,psa 8.3, DRE normal, no symptoms.Is pirads 5 indicative of aggression, biopsy will obviously show diagnosis.

Psa picked up on a requested blood test after much cajoling from me particularly in light of family history.

Bastard disease, got fingers crossed for him.

[petabyte]

I was also pirads 5 which my uro said probably indicated aggressive PCa.

[dentaltwin]

PIRADS 5 means high risk for CLINICALLY-SIGNIFICANT cancer, NOT "aggressive" cancer. The biopsy will give a better idea of how aggressive the tumor is likely to be.

I was PIRADS 5, "highly likely" extracapsular extension. But the post-op path did NOT show EPE, and 6 1/2 years after RP there has been no evidence of residual disease. So the finer points of the situation can change over time.

[MNFarmBoy]

Hi, pd63, below I copied the descriptions of PI-RADS that was included in the report on which the urologist prescribed a biopsy after PSA had increased from 10.4 to 14.2 ng/ml over 2 years:

Quote:

IMPRESSION:

1. Findings compatible with new PI-RADS IV lesion measuring 7 mm in the left anterior transition zone, PI-RADS IV

Prostate Imaging-Reporting and Data System (PIRADS-V2):

* PI-RADS I = Very low likelihood of clinically significant cancer

* PI-RADS II = Low likelihood of clinically significant cancer

* PI-RADS III = Indeterminate

* PI-RADS IV = High likelihood of clinically significant cancer

* PI-RADS V = Very high likelihood of clinically significant cancer

NOTE:

The PI-RADS classification of prostate lesions has been adopted to standardize MRI scan reporting. Current MRI technique and criteria are tailored for detection of clinically significant cancer.

PI-RADS criteria and documentation are available online at

acr.org/Quality-Safety/Reso....

Unquote

In the report from my first MRI, done 2 years prior to the above, the radiologist stated "IMPRESSION: No suspicious index lesion in the prostate gland", with no statement of any observed PI-RADS, but including a description similar to the above of the PI-RADS levels.

Best wishes for the best possible out-come!

[Mike404]

as has been stated, Pirads 5 means high likelihood of cancer, nothing about type. The Gleason score from the biopsy will indicate how “aggressive” it is, with Gleason 5 the highest. Two different 1 to 5 measures.

I was Pirads 5 with a Gleason “4+”, G4 with cribriform. However, my Dechiper score (a genetic test you can add to your biopsy) was only .19, low risk. We still played it safe on treatment plans. Good luck.