August 2024 diagnosed Gleason 3+4=7, 8 of 12 cores, Tumor 2TC, Pirads 4 (5mm), Pirads 5 (16 mm X 35mm), No extra capsular extension. No seminal vesicle invasion.
PSA 49.9, 58.3, 52.5 and 59.2.
Awaiting results of PSMA PET/CT Gallium 68.
Has anyone else had high and erratic PSA in this range? If yes what was the result of your staging?
Regards,
There’s nothing erratic about it. Your PSA is fucking high! I’d be very surprised if the cancer hasn’t escaped the prostate. My radiologist said 20% of MRI’s are inaccurate. Get on it man!
Just before starting treatment, mine was 200, up from 100 two months earlier. I've seen others report much higher. Many have said that what matters more than the pre-treatment level is how well PSA responds to the treatment. Does it collapse down to (hopefully) 1 or well under (may depend partially on whether you still have your prostate).
But I defer to others more versed on that specific issue
BPH can cause high PSA. Your PSMA will likely give you the answer as to whether you are metastatic. Good luck
my PSA was 37.01 on my first test ever and 33.75 on my second test (three weeks later). MRI suspected possible extracapsular extension. Single big-ass tumor that was about 2.4cm. Gleason 4+3. Had surgery 11-2023. Organ confined disease on the final pathology and PSAs have been <0.006 on the Labcorp test ever since. I know I’m a higher risk for recurrence but so far so good.
That's a great result!! Good luck to ya!!
Newbie. Increasing psa. What to do next?
My own PSA values over time: 70% drop in just 3 months on Dutasteride and no ADT
High PSA upon diagnosis, treatment , and outcome 
PSA is back
New biopsy: now G4+3
