hello I am a 67 year old that was diagnosed with prostate cancer 18 years ago Gleason score 7 t1c psa 8.s Had 38 treatments of radiation { 3 gold seeds} .nadir was .1 after 8 years went to .2 doctor was not concerned, started doing blood work at famliy doctor psa went to .3 { different labs? } stayed there 6 years I figured I was out of the woods so didnt have it tested since 2022. six months ago I went to urologist for kidney cysts, he went a head and did a digital check on prostate was fine did psa it came back at .58. doctor knew about radiation treatment but didnt ask about previous psa numbers. told me come back in six months did psa went to .72, doctor at the time of the visit did not have this result told me see you in six months. Guess I am worried that caner has came back after 18 years or is this increase natural thanks for any ones input
why would psa be going up after 18 years - Prostate Cancer N...
why would psa be going up after 18 years
You still have a prostate, and you will always have PSA and PSA fluctuations. It is more likely due to inflammation than prostate cancer. That's why they set nadir+2.0 (which in your case would be a PSA of 2.2 ng/ml) as the "biochemical recurrence" after primary radiation therapy. At that level, they might investigate to see if there is a clinical recurrence if there is no benign explanation.
just did have a cat scan done for a small intestinal blockage 7 months aga go { no color allergic to the dye} didnt pick anything up just the gold seeds in the prostate if that means anything also road a stationary bike 45 minutes the last three days before the .58 to .72 bounce witch maybe contributed to increase. also could it just be age related would it not be rare for a reoccurrence after all this time. I guess you can tell I am worried it.
That may be one of your top most reassuring answers. Having just completed radiation, after quizzing my RO, I'm still not clear if I still have a functioning prostate.
Yes, you do.
That seems to jive with his answer. I thought radiation essentially destroyed its functionality.
Functioning?
The function of the prostate is to manufacture semen. According to these trials, ejaculatory volume decreased after radiation, but was seldom (15%) completely lost:
academic.oup.com/jsm/articl...
redjournal.org/article/S036...
There is also a contraction of the prostate that we associate with the feeling of orgasm. This is not lost either.
Hi Tall, how do you think that compares to IMRT? I'm on 2 years ADT , so excluded from that anyways. Also is there a difference in short or long SE between 5 day 35gy and 28 day 70gy? Thanks
I'd assume it would be similar.
Thanks Tall Allen, has there been any research on the 35gy against 70gy for SE? Thanks
Yes. Very little difference-- none if the right equipment is used for SBRT.
I did get radiation-induced colitis from from therapy that showed up on my colonoscopy in 2007 and 2012 but not in 2018 but still have symptoms of it to this day. Could that be whats causing the slow gradual raise in my psa. thanks for your time
No.
I'm no expert but if you're prostate isn't removed and with your age, I would assume your PSA is within the normal range.
Thanks for everybody's input, just going to have to monitor my psa levels. Just going over the site and was reading about a gentleman who just recently had a reoccurrence after 18 years his circumstances are very similar, I which him the best. Over the last 18 years I am sure they have come a long way at battling this form of cancer. thanks again for everybodys input
did want to add good luck to all in your battle against this persistent form of cancer
wondering been reading conflicting reports can using a exercise bike three days in a row for forty minutes right before the test cause a raise in psa readings like from .58 to .72
YES!!
High PSA after surgery
Recurrence six-years after surgery
Rising PSA 18 months post LD Brachytherapy
PSA still going up
27 months post 39 sessions of EBRT and completion of 3 years of ADT my PSA remains at <=0.08
