Thrush in mouth

[Smokygirl]

I have had oral thrush for a couple of months now, Treated it with Corsodyl mouthwash to no avail. Got Nystan mouthwash off Doc last week and five days later —- no better. Any advice would be appreciated. Doc is calling me later this afternoon.

[PMRpro Ambassador]

You may need a lot longer if it is well embedded in your body. The Mayo says 3 to up to 14 days,

I needed oral nystatin to swallow - and that was thrush not due to pred!

[Smokygirl in reply to PMRpro]

Thanks PMRpro. I thought I’d ask him for some Nystatin tablets as well as the mouthwash.

[PMRpro Ambassador in reply to Smokygirl]

Can you get them again? I needed them for months and it made such a difference. But then they stopped prescribing them - years ago mind!

[Smokygirl in reply to PMRpro]

Yes. I’ve just spoken to the Doc and he has prescribed the Nystatin tablets for me. Get them tomorrow. Hope they work. He said give it 7 days and phone him again if no improvement.

[Smokygirl in reply to PMRpro]

You may be right PMRpro, to my surprise the Doc has given me Fluconazole capsules —- maybe Nystatin pills are still hard to come by, or Fluconazole is, as you say, the better option! Crossed fingers!

[DorsetLady PMRGCAuk volunteer]

I needed s couple of courses of Nystatin to get rid of mine.

But once gone, never returned.

[Smokygirl in reply to DorsetLady]

Thanks DL. I get them tomorrow. I really hope they work. I have to phone the Doc in 7 days if no improvement but I’ll bear in mind your experience of needing two courses. xxx

[SnazzyD]

Hello. Sounds like the duration of treatment wasn’t long enough as PMRPro says. The Corsodyl, if it was a basic Chlorhexidine type, isnt very antifungal. When I had oral thrush and inflammation with chemo, I found that the Corsodyl itself was causing the inflammation to intensify as it was such an irritant.

[PMRpro Ambassador in reply to SnazzyD]

You just poked my memory!

pubmed.ncbi.nlm.nih.gov/296...

"This study showed that 200 μM farnesol modulated C. albicans in a dual-species biofilm with S. mutans, but did not exhibit antimicrobial activity against S. mutans. Moreover, it seems that S. mutans provides conditions that support the growth of the yeast form of C. albicans. The mouthwash Corsodyl® reduces S. mutans, but was not effective against C. albicans."

If your thrush is due to C Albicans - Corsodyl won't work ...

[Smokygirl in reply to PMRpro]

Interesting because Corsodyl cleared my inner cheeks but not my tongue or inside lip. Perhaps I’ve got both forms of yeast.......

[PMRpro Ambassador in reply to Smokygirl]

Seems a possibility according to the paper ...

[yorkieme]

Hope this doesn't confuse the debate but having tried Nystatin,which failed,I am now 1 week of 2 inti Fluconazole which does seem to be working.

[PMRpro Ambassador in reply to yorkieme]

pubmed.ncbi.nlm.nih.gov/976...

Seems you might be on to the better option!

[yorkieme in reply to PMRpro]

Hooray ! One round to me. lol.

[Smokygirl in reply to yorkieme]

Yup—- me too just started. I was expecting Nystatin so am quite surprised that the Doc changed it to Fluconazole. Here’s hoping!

[Cherrymoon]

Hello, my first venture into replying, rather than reading.

Baking soda (sodium bicardonate) I had a good result. Half teaspoon of baking soda in cup of warm water, swish well and spit.... I may have gone for a bit more soda!

I did changed my tooth brush more often, but not daily as recommended with thrush being fungal.

[Phoenix51]

This post resonates with me .. I have had sore tongue, burning sensation and bitter taste in my mouth for 2 months, the only thing that resolved it is eating 🤦‍♀️. Dr prescribed nystatin as thought it may be oral thrush as it can be a side effect of Pred. Took it for a week with no improvement so she then prescribed daktsrin gell, tried this for a week, no improvement. In the meantime dr sent me a mouth swob. I heard yesterday that this came back negative but dr sats this can happen if you’ve been on treatment so she has now prescribed a different tablet to try but is also sending me for blood tests to test for B12, thyroid and diabetes. Last night I googled burning tongue as my tongue feels as it does when you’ve eaten soup that’s too hot! I came across lots of information on Burning Mouth Syndrome, it can be related to auto immune illness and the symptoms tally exactly with mine, I’m keeping my fingers crossed it’s not that as it can continue for years and there is no treatment but whatever it is a just want to get rid of it, between that and the blurred vision I’m feeling fed up. Good luck and I hope the latest treatment works .. good advice from others to stick the treatment out for longer than a week.

[York54 in reply to Phoenix51]

I had exactly your symptoms too, after lots of courses of Nystatin drops , my GP referred me to the hospital. I have a patch of lichen planus on the inside of my cheek too. He diagnosed burning mouth syndrome too. No treatment , can be stress related. I have it again now, I bought some biotene mouthwash for dry mouth. It helps a little as does chewing sugar free gum. On a follow up appointment the chap I saw then suggested diluting a 1 mg pred tablet and swishing it around my mouth as sometimes it can be really sore. 🙁🙁

[Phoenix51 in reply to York54]

Thank you York54 . I will try your advice. It’s awful isn’t it? Im kind of hoping it is oral thrush rather than BMS as there is no cure. good luck, I hope things improve for you

[York54 in reply to Phoenix51]

Mine comes and goes, being stressed doesn’t help me ☹️

[Smokygirl in reply to York54]

Oh York—- It’s just not fair is it? My tongue feels slightly burnt too!!

The Sugar free chewing gum is great but sadly gives me stomach ache!

[York54 in reply to Smokygirl]

Oh no, I hope the fluconazole helps 👍👍👍

[Smokygirl in reply to York54]

Yes. The Fluconazole has cleared 90% of the thrush. My Doc has just prescribed me a second course to hopefully get rid of it completely.

He says that some people need a very small therapeutic dose for a long time If it that does not clear it all.

[York54 in reply to Smokygirl]

That’s good news, glad it has been resolved. The consultant I saw ages ago said mine wasnt thrush. I’m diabetic and take metformin so I can get yeasty things if my sugar gets a bit high, but at the other end 😂lol

[Smokygirl in reply to Phoenix51]

Thanks So much Phoenix. It’s a bugger isn’t it!! My Doc has changed my meds already after five days from a Nystatin mouth wash to Fluconazole pills for a week. Crossed fingers and I’ll let you know the outcome!

[Phoenix51 in reply to Smokygirl]

please do, good luck

[Smokygirl in reply to Phoenix51]

Thrush cleared 90% after a week of Fluconazole. Been given another weeks supply.

[Phoenix51 in reply to Smokygirl]

Good news! I’m so pleased that you have had success. I am taking my last fluconazole today but I still have the burning tongue and sour taste in mouth. I’m beginning to think it’s not thrush after all but burning tongue syndrome or acid reflux/GERD. Whatever it is I wish I didn't have it!

[Smokygirl in reply to Phoenix51]

Hi Phoenix. Although it is 90% improved, I also still have the foul taste in my mouth, and a very slight white coating on my tongue in the morning when I wake up. I have just started my second week of Fluconazole and am now also using Corsodyl mouthwash as well. I also steep my toothbrush in diluted 6% Hydrogen peroxide Solution after every use.

Have you spoken to your Doc again?

[Phoenix51]

mayoclinic.org/diseases-con...

[Iwillwin123]

Please check it is not tongue claudication . It is very rare but I had it in the intial stage of pred at 60 mg . I was also taking Folitrax then . We discontinued it and somehow the Claudication settled down . We still do not know Reliably how it got resolved though .......

[Smokygirl in reply to Iwillwin123]

I really think it’s thrush—-there is no pain or redness on the tongue , just a white coating on it and also on my inner lip which I can wipe off.

[Iwillwin123 in reply to Smokygirl]

Yes I agree that if there is no pain - then it must be thrush....... I remembered how terrible the misdiagnosis for me was ...... and therefore just gave my narrative. If it was claudication there would be intense pain coupled with a whitish reddish coloration on tongue ........ If no pain then obviously it is thrush

[Iwillwin123]

Also no doctor was ready to believe it was tongue claudication . The symptoms were severe burning and pain in tongue especially on eating food , severe redness of tongue esp on sides and the mouth as well and the docs kept insisting it was thrush and treating it so with no results.

[rocketman42]

If it is Thrush ( Candida Albicans ) then ask your doctor to prescribe Mycelex Troches. This works better than Nystatin.

[Smokygirl in reply to rocketman42]

Thanks R! I’ve noted it and if this course of Fluconazole that I’ve just started doesn’t work, I’ll ask the Doc. BTW I was expecting Nystatin!

[Adelee1961]

Hi there is a product from Canesten specifically for mouth thrush I’ve found effective.

[Smokygirl in reply to Adelee1961]

Thanks Adele! My Doc has just given me weeks supply of Fluconazole. Was that it? I have to say that Canesten never worked for me years ago and I know that they used to prescribe them together. Oh well—- fingers crossed!

[Amkoffee]

I use Clotrimazole 10 mg troche. If you have an active infection you suck on one of these five times a day for either a week or 10 days I can't remember, and they're actually quite tasty. I have to take it prophylactically to keep me from getting thrush because I get it so easily.