I heard an interesting interview with Dr Edward Bullmore on Start the Week BBC Radio 4 this morning. As far as I understood, he thinks that the release of Cytokines when our immune system is activated or over active, as in auto immune diseases, can have an effect on the brain and be a cause of depression. He also has an idea that anti inflammatory drugs could help with depression for this reason. He relates stress with inflammatory conditions which in turn affect the brain causing depression in a cyclical fashion. He has written a book "The Inflamed Mind" and talks about his theory in the Youtube lecture linked below. I'd be interested to see your comments or to know if you've heard about his theory. Maybe he should hear about our PMR experiences.
Connections between inflammation, the immune syst... - PMRGCAuk
This is interesting but, speaking personally, I am definitely less depressed - or at least depressed less often - than before GCA. Seem to have developed a tremendous amount of acceptance and equanimity. Could it be the pred?
Maybe it's just that I now have a genuine reason for being a grumpy so-and-so - which makes it ok?