Just came from the doctor. Inflamatory markers are up again. I just can not seem to get them down. This time I do have a cold last time a uti. It seems as soon as I drop from20mg I flare again. This has been going on since August. I was diagnosed by a biopsy in April. I think my doctor is frustrated too he suggested a referral to Mayo. We are going to try more frequent labs just to see if the flares are caused by not my feeling well. As soon as the cold is gone I will get it checked again.