Quick question if anyone could help
We have recently been back with the consultant with my dad who is being treated for R/A / PMR. He would like my farther to go back on Humira & MTX and come off his current 30mg pred. We raised a concern with tis due to my dad being hospitalised twice with sepsis infection 12 days after his first trial of humira and 5 days after the second trial 2 month later.
Based on the fact that my farther has had no R/A - PMR pain for over 3 months (Only fatigue) we suggested that he reduces the pred without other treatment and see how he goes. Reluctantly the consultant agreed with this and proposed 30-20mg from Monday - 20-15mg 2 weeks later 15-10 2 weeks later 10-5 2 weeks later.
When we questioned the reason he would like us to go on with the Humira we were informed that his CRP rate dropped the first time he had Humira and since has raised back up.
My question is, obviously something is controlling the severe pain which he previously had for over 10 months until his pred went up to 50mg in July. If the pred was controlling the pain why would the CRP rate be so high when he has no pain (Could the ESR level be high for other reasons away from the R/A PMR) And would it be normal to use the CRP / ESR data over pain symptoms when analysing and implementing treatment plans.
Tanks again, massive support for our family