Has anyone taken Methotrexate? My Dr. wants me to start taking that with my Prednisone to help me wean off the prednisone. Was originally 60 in December, and then finally down to 20 month ago, but back up to 40 as all my symptoms. Had biopsy, positive for GMC. Reading all side effects and thinking I don't want to go on this drug. I think side effects of Prednisone is not nearly as bad as this drug!! I am just so scared, as do not do well with drugs, and have so many allergic allergies to antibiotics and drugs. This drug sounds really scary, even pharmacy said really read side effects before you decide to take it. Plus only have one kidney. Says bad on liver, etc. Would love feed back. Live in NJ but going to doctors in Phila., Pa. But you guys in UK are so much more knowledgeable abut GCA I love this site. Any feed back you give me would be greatly appreciated. So sick for 4 weeks with sever diarrhea had in 4 days, ultra sound, Cat Scan and MRI all came back fine, stool tests, etc. Not sure I if is Prednisone or what. Since Dec. and now have to take Blood Pressure medicine and now they think may have diabetis.