Hi, new to the forum. My husband has been 'ill' for approx two years, investigations (slow NHS) have finally given diagnosis of AMA positive through blood tests, also he is having complex partial seizures several times a day, he had been diagnosed with diabetes, and has recently had lumbar puncture to check for other auto-immune problems (I think!) but we are still waiting for the results. He has been bleeding from his back passage and occasionally vomits blood. He is currently waiting to see a Gasterenterologist in a couple of weeks time. He had a signoidoscopy two weeks ago in which they removed polyps and did some pile banding, but his bleeding continues. He has not yet seen any form of specialist re PBC so do not know what stage he is at, but concerned about the bleeding. Is it normal to bleed with PBC? And also are you more susceptible to other auto-immune diseases with PBC? does anyone know whether there is a connection with the seizures? His symptoms in relation to the PBC are excessive fatigue, itching, red rash, and he suddenly cannot tolerate any alcohol whatsoever, it makes him feel so ill, even just a small amount. Any advice would be appreciated.