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Unfortunately, liver biopsy has been offered far too often, and incorrectly as a method of diagnosis in the past,’ explains Professor Jones. ‘In fact, in around 90% of cases, AMA and LFT tests together can provide a definite diagnosis of PBC.
‘Crucially, if you have had AMA and LFT (usually Alk Phos) tests which confirm you have PBC you do not need usually a liver biopsy for diagnostic purposes. Sometimes a biopsy will help with diagnosis and management but your doctor should be able to explain why this is the case, specifically.’